Moderate alcohol consumption reduces plasma C-reactive protein and fibrinogen levels; a randomized, diet-controlled intervention study

European Journal of Clinical Nutrition

Volumn 56, Issue 11, 2002, Pages 1130-1136

  Sierksma, A ^a,b   van der Gaag, M S ^a   Kluft, C ^a   Hendriks, H F J ^a  

^a TNO   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Alcohol; Atherosclerosis; C reactive protein; Fibrinogen; Inflammation

Indexed keywords

ACETYLSALICYLIC ACID; ACUTE PHASE PROTEIN; ALANINE AMINOTRANSFERASE; ALCOHOL; ASPARTATE AMINOTRANSFERASE; C REACTIVE PROTEIN; ESTRADIOL; FIBRINOGEN; FOLLITROPIN; GAMMA GLUTAMYLTRANSFERASE; GLUCOSE; HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PARACETAMOL; TRIACYLGLYCEROL;

ADULT; ALCOHOL CONSUMPTION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BEER; CARDIOVASCULAR RISK; CIGARETTE SMOKING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIET THERAPY; FEMALE; FIBRINOGEN BLOOD LEVEL; FOOD COMPOSITION; HUMAN; HUMAN EXPERIMENT; MALE; NETHERLANDS; NORMAL HUMAN; POSTMENOPAUSE; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL;

ALCOHOL DRINKING; BEER; C-REACTIVE PROTEIN; CARDIOVASCULAR DISEASES; CHOLESTEROL, HDL; CROSS-OVER STUDIES; DIET; FEMALE; FIBRINOGEN; HUMANS; LIVER; MALE; MIDDLE AGED; POSTMENOPAUSE; TRIGLYCERIDES;

EID: 0036856471     PISSN: 09543007     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ejcn.1601459     Document Type: Article

References (36)

1. Anonymous (1995): Guideline for Good Clinical Practice, CPMP/ICH/135. International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use.
2. Anonymous (1998): Zo eet Nederland, Resultaten van de voedselconsumptiepeiling 1997-1998. Den Haag: Voedingscentrum.
3. Blanco-Colio LM, Valderrama M, Alvarez-Sala LA, Bustos C, Ortego M, Hernández-Presa MA, Cancelas P, Gómez-Gerique J, Millán J & Egido J (2000): Red wine intake prevents Nuclear Factor-κB activation in peripheral blood mononuclear cells of healthy volunteers during postprandial lipemia. Circulation 102, 1020-1026.
4. De Maat MP, De Bart AC, Hennis BC, Meijer P, Havelaar AC, Mulder PG & Kluft C (1996): Interindividual and intraindividual variability in plasma fibrinogen, TPA antigen, PAI activity, and CRP in healthy, young volunteers and patients with angina pectoris. Aterterioscler. Thromb. Vasc. Biol. 16, 1156-1162.
5. Dimmitt SB, Rakic V, Puddey IB, Baker R, Oostryck R, Adams MJ, Chesterman CN, Burke V & Beilin LJ (1998): The effects of alcohol on coagulation and fibrinolytic factors: a controlled trial. Blood Coagul. Fibrinol. 9, 39-45.
6. Ford ES (1999): Body mass index, diabetes, and C-reactive protein among U.S. adults. Diabetes Care 22, 1971-1977.
7. Gram J, Bladbjerg EM, Moller L, Sjol A & Jespersen J (2000): Tissue-type plasminogen activator and C-reactive protein in acute coronary heart disease. A nested case-control study. J. Intern. Med. 247, 205-212.
8. Harris TB, Ferrucci L, Tracy RP, Corti MC, Wacholder S, Ettinger WH Jr, Heimovitz H, Cohen HJ & Wallace R (1999): Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly. Am. J. Med. 106, 506-512.
9. Hendriks HFJ & Van der Gaag MS (1998): Alcohol, coagulation and fibrinolysis. In: Alcohol and Cardiovascular Diseases (Novartis Foundation Symposium 216), ed. DJ Chadwick & JA Goode, pp 111-124. Chichester: John Wiley.
10. Hendriks HFJ, Veenstra J, Velthuis-te Wierik EJM, Schaafsma G & Kluft C (1994): Effect of moderate dose of alcohol with evening meal on fibrinolytic factors. Br. Med. J. 308, 1003-1006.
11. Hendriks HFJ, Veenstra J, Van Tol A, Groener JEM & Schaafsma G (1998): Moderate doses of alcoholic beverages with dinner and postprandial high density lipoprotein composition. Alcohol Alcohol. 33, 403-410.
12. Iacoviello L, Zito F, Di Castelnuovo A, De Maat M, Kluft C & Donati MB (1998): Contribution of factor VII, fibrinogen and fibrinolytic components to the risk of ischaemic cardiovascular disease: their genetic determinants. Fibrinol. Proteol. 12, 259-276.
13. Imhof A, Froehlich M, Brenner H, Boeing H, Pepys MB & Koenig W (2001): Effect of alcohol consumption on systemic markers of inflammation. Lancet 357, 763-767.
14. Koenig W & Wanner K (1999): C-Reactive protein and coronary artery disease - what is the link? Nephrol. Dial. Transplant. 14, 2798-2800.
15. Koenig W, Sund M, Fröhlich M, Fischer HG, Lowel H, Doring A, Hutchinson WL & Pepys MB (1999): C-Reactive protein, a sensitive marker of inflammation, predicts future risk of coronary heart disease in initially healthy middle-aged men. Circulation 99, 237-242.
16. Kuller LH, Tracy RP, Shaten J & Meilahn EN (1996): Relation of C-reactive protein and coronary heart disease in the MRFIT nested case-control study. Am. J. Epidemiol. 144, 537-547.
17. Mendall MA, Patel P, Ballam L, Strachan D & Northfield TC (1996): C-Reactive protein and its relation to cardiovascular risk factors: a population based cross sectional study. Br. Med. J. 312, 1061-1065.
18. Mezzano D, Leighton F, Martínez C, Marshall G, Cuevas A, Castillo O, Panes O, Muñoz B, Pérez DD, Mizón C, Rozowski J, San Martín A & Pereira J (2001): Complementary effect of Mediterranean diet and moderate red wine intake on haemostatic cardiovascular risk factors. Eur. J. Clin. Nutr. 55, 444-451.
19. Pellegrini N, Pareti FI, Stabile F, Brusamolino A & Simonetti P (1996): Effects of moderate consumption of red wine on platelet aggregation and haemostatic variables in healthy volunteers. Eur. J. Clin. Nutr. 50, 209-213.
20. Pepys MB (1996): The acute phase response and C-reactive protein. In: Oxford Textbook of Medicine, ed. DJ Weatherall, JGG Ledingham & DA Warrell, pp 1527-1533. New York: Oxford University Press.
21. Pikaar NA, Wedel M & Hermus RJJ (1988): Influence of several factors on blood alcohol concentrations after drinking alcohol. Alcohol Alcohol. 23, 289-297.
22. Ridker PM, Cushman M, Stampfer MJ, Tracy RP & Hennekens CH (1997): Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. New Engl. J. Med. 336, 973-979.
23. Ridker PM, Buring JE, Shih J, Matias M & Hennekens CH (1998): Prospective study of C-reactive protein and the risk of future cardiovascular events among apparently healthy women. Circulation 98, 731-733.
24. Ridker PM, Hennekens CH, Buring JE & Rifai N (2000): C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. New Engl. J. Med. 342, 836-843.
25. Rumpler WV, Rhodes DG, Baer DJ, Conway JM & Seale JL (1996): Energy value of moderate alcohol consumption by humans. Am. J. Clin. Nutr. 64, 108-114.
26. Schofield WN (1985): Predicting basal metabolic rate, new standards and review of previous work. Hum. Nutr. Clin. Nutr. 39 (Suppl 1), 5-41.
27. Snedecor GW & Cochran WG (1980): Statistical Methods, 7th edn, p 1. Ames, IA: The Iowa State University Press.
28. Strandberg TE & Tilvis RS (2000): C-Reactive protein, cardiovascular risk factors, and mortality in a prospective study in the elderly. Arterioscler. Thromb. Vasc. Biol. 20, 1057-1060.
29. Strandberg TE, Vanhanen H & Tikkanen MJ (2000): Associations between change in C-reactive protein and serum lipids during statin treatment. Ann. Med. 32, 579-583.
30. Tracy RP, Lemaitre RN, Psaty BM, Ives DG, Evans RW, Cushman M, Meilahn EN & Kuller LH (1997): Relationship of C-reactive protein to risk of cardiovascular disease in the elderly. Results from the cardiovascular health study and the rural health promotion project. Arterioscler. Throm. Vasc. Biol. 17, 1121-1127.
31. Van der Gaag MS, Van Tol A, Scheek LM, James RW, Urgert R, Schaafsma G & Hendriks HFJ (1999): Daily moderate alcohol consumption increases serum paraoxonase activity; a diet-controlled, randomised intervention study in middle-aged men. Atherosclerosis 147, 405-410.
32. Van der Gaag MS, Van Tol A, Vermunt SHF, Scheek LM, Schaafsma G & Hendris HFJ (2001): Alcohol consumption stimulates early steps in reverse cholesterol transport. J. Lipid Res. 42, 2077-2083.
33. Visser M, Bouter LM, McQuillan GM, Wener MH & Harris TB (1999): Elevated C-reactive protein levels in overweight and obese adults. JAMA 282, 2131-2135.
34. Von Clauss A (1957): Gerinnungsphysiologische Schnellmethode zur Bestimmung des Fibrinogens. Acta Haematol. 17, 231-237.
35. Wedel M, Pieters JE, Pikaar NA & Ockhuizen T (1991): Application of a three-compartment model to a study of the effects of sex, alcohol dose and concentration, exercise and food consumption on the pharmacokinetics of ethanol in healthy volunteers. Alcohol Alcohol. 26, 329-336.
36. Westerterp KR (1996): Effect of moderate alcohol consumption on energy expenditure. Alcohol Res. 1, 187-189.