Antifibrotic action of interferons? The internist point of view;Les interférons ont-ils une action antifibrosante ? Le point de vue de l'interniste

Revue de Medecine Interne

Volumn 23, Issue SUPPL. 4, 2002, Pages

  Bletry O ^a   Somogyi, A ^a  

^a FOCH HOSPITAL   (France)

Author keywords

Cutaneous radiation syndrome; Idiopathic pulmonary fibrosis; Interferon alpha; Interferon gamma; Progressive systemic sclerosis

Indexed keywords

ALPHA INTERFERON; ANTIFIBROTIC AGENT; GAMMA INTERFERON; INTERFERON; TRANSFORMING GROWTH FACTOR;

CANCER RADIOTHERAPY; CHERNOBYL ACCIDENT; CLINICAL TRIAL; COLLAGEN SYNTHESIS; DRUG EFFICACY; DRUG MECHANISM; FIBROSIS; HEPATITIS C; HUMAN; LUNG FIBROSIS; NONHUMAN; RADIATION INJURY; REVIEW; SIDE EFFECT; SKIN FIBROSIS; SURVIVAL; SYSTEMIC SCLEROSIS;

EID: 0036855128     PISSN: 02488663     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0248-8663(02)00667-7     Document Type: Article

References (27)

1. Poynard T. Les interférons ont-ils une action antifibrosante ? Le point de vue de I'hépatologue. Rev Méd Interne 2002;23:517-21.
2. Domingues MA, Haepers AT, Massaut IH, Vassallo J, Lorand-Metze I. Reversal of bone marrow fibrosis in idiopathic myelofibrosis after treatment with alpha interferon. Haematologica 1998;83:1124-5.
3. Bachleitner-Hofmann T, Gisslinger H. The role of interferon alpha in the treatment of idiopathic myelofibrosis. Ann Hématol 1999;78:533-8.
4. Tredget EE, Wang R, Shen Q, Scott PG, Ghahary A. Transforming growth factor-beta mRNA and protein in hypertrophic scar tissues and fibroblasts: Antagonism by IFN-alpha and IFN-gamma in vitro and in vivo. J Interferon Cytokine Res 2000;20:143-51.
5. Giri SN, Hyde DM, Marafino BJ. Ameliorating effect of murine interferon gamma on bleomycin-induced lung collagen fibrosis in mice. Biochemical Med Metab Biol 1986;36:194-7.
6. Berkman N, Kremer S, Or R, Lossos IS, Christensen TG, Goldstein RH, Breuer R. Human recombinant interferon alpha 2a and interferon alpha A/D have different effects on bleomycine-induced lung injury. Respiration 2001;68:169-77.
7. Rosiello RA, Merrill WW, Rockwell S, Carter D, Cooper JA, Care S, Amento EP. Radiation pneumonitis. Bronchoalveolar lavage assessment and modulation by a recomibnant cytokine. Am Rev Resp Dis 1993;148:1671-6.
8. Keane MP, Belperio JA, Arenberg DA, Burdick MD, Xu ZJ, Strieter RM. IFN-gamma-inducible protein-10 attenuates bleomycin-induced pulmonary fibrosis via inhibition of angiogenesis. J Immunol 1999;163:5686-92.
9. Oldroyd SD, Thomas GL, Gabbiani G, El Nahas AM. Interferon gamma inhibits experimental renal fibrosis. Kidney Internat 1999;56:2116-27.
10. Ziesche R, Block LH. Mechanisms of antifibrotic action of interferon gamma-1b in pulmonary fibrosis. Wiener Klin Wochenschrift 2000;112:785-90.
11. Sime PJ, O'Reilly KM. Fibrosis of the lung and other tissues: New concepts in pathogenesis and treatment. Clin Immunol 2001;99:308-19.
12. Ziesche R, Hofbauer E, Wittmann K, Petkov V, Block LH. A preliminary study of long-term treatment with interferon gamma-lb and low-dose prednisolone in patients with idiopathic pulmonary fibrosis. N Engl J Med 1999;341:1264-9.
13. Peter RU, Gottlober P, Nadeshina N, Krahn G, BraunFalco O, Plewig G. Interferon gamma in survivors of the Chernobyl power plant accident: New therapeutic option of radiation-induced fibrosis. Inter J Rad Oncol Biol Phys 1999;45:147-52.
14. Gottlober P, Steinert M, Bahren W, Weber L, Gerngross H, Peter RU. Interferon gamma in 5 patients with cutaneous radiation syndrome after radiation therapy. Intern J Rad Oncol Biol Phys 2001;50:159-66.
15. Haque MF, Meghji S, Nazir R, Haris M. Interferon gamma (IFN-gamma) may reverse oral submucous fibrosis. J Oral Pathol Med 2001;30:12-21.
16. Krieg T, Meurer M. Systemic scleroderma. Clinical and pathophysiologic aspects. J Am Acad Derm 1988;18,3:457-81.
17. Border WA, Noble NA. Mechanisms of disease. transforming growth factor beta in tissue fibrosis. N Engl J Med 1994;331:1286-92.
18. Roberts AB, Sporn MB, Assoian RK, Smith JM, Roche NS, Wakefield LM, et al. Transforming growth factor β: Rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc Natl Acad Sci USA 1986;83:4167-71.
19. Rosenbloom J, Feldman G, Freundlich B, Jimenez SA. Inhibition of excessive scleroderma fibroblast collagen production by recombinant gamma interferon. Association with a coordinate decrease in types I and III procollagen messenger RNA levels. Arthritis Rheum 1986;29:851-6.
20. Kähäri VM, Heino T, Vuorio E. Interferon alpha and interferon gamma reduce excessive collagen synthesis and procollagen mRNA levels of scleroderma fibroblasts in culture. Biochim Biophys Acta 1988;968:45-50.
21. Gillery P, Serpier H, Polette M, Bellon G, Clavel C, Wegrowski Y, et al. Gamma interferon inhibits extracellular matrix synthesis and remodeling in collagen lattice cultures of normal and scleroderma skin fibroblasts. Europ J Cell Biol 1992;57:244-53.
22. Kahan A, Amor B, Menkes CJ, Strauch G. Recombinant interferon gamma in the treatment of systemic sclerosis. Am J Med 1989;87:273-6.
23. Gilkrson GS, Polisson RP, Simon L, Smith EA. Gamma interferon in systemic sclerosis a multicenter trial. Arthritis Rheum 1990;33(Suppl):65.
24. Laraki R, Blétry O, Francès C, Cabane J, Brandely M, Godeau P. Treatment of systemic sclerosis by gamma interferon about forteen cases. J Interferon Res 1991;11:92 [abstract].
25. Freundlich B, Jimenez SA, Steen VD, Medsger TA, Szkolnicki M, Jaffe HS. Treatment of systemic sclerosis with recombinant interferon gamma. A phase I/II clinical trial. Arthritis Rheum 1992;35:1134-42.
26. Blétry O, Laraki R, Cabane J, Frances C, Piette JC, Soubrier M, et al. Résultats à long terme du traitement des sclérodermies systémiques diffuses par l'interféron gamma. Rev Méd Interne 1993;14:978.
27. Barnett AJ, Miller MH, Littlejohn GO. A survival study of patients with scleroderma diagnosed over 30 years (1953-1983). The value of a simple cutaneous classification in the early stages of the disease. J Rheumatol 1988;15:276-83.