Copper- and zinc-containing superoxide dismutase (Cu/ZnSOD) is required for the protection of Candida albicans against oxidative stresses and the expression of its full virulence

Microbiology

Volumn 148, Issue 11, 2002, Pages 3705-3713

  Hwang, Cheol Sang ^a   Rhie, Gi Eun ^a   Oh, Jang Hyun ^a   Huh, Won Ki ^a   Yim, Hyung Soon ^a   Kang, Sa Ouk ^a  

^a Seoul National University   (South Korea)

Author keywords

Candidiasis; Hyphal growth; Lysine auxotrophy; SOD1

Indexed keywords

ANTIOXIDANT; COPPER ZINC SUPEROXIDE DISMUTASE; LYSINE; MENADIONE; SUPEROXIDE DISMUTASE; VIRULENCE FACTOR;

ANTIOXIDANT ACTIVITY; CANDIDA ALBICANS; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVITY; FEMALE; FUNGAL CELL; FUNGUS GROWTH; FUNGUS HYPHAE; FUNGUS MUTANT; GROWTH RATE; MACROPHAGE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REVIEW; SENSITIVITY ANALYSIS; SERUM; SPIDER; TECHNIQUE; VIRULENCE; WILD TYPE;

ANIMALIA; ARANEAE; CANDIDA ALBICANS; FUNGI;

EID: 0036854503     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/00221287-148-11-3705     Document Type: Review

References (37)

1. Battistoni, A., Donnarumma, G., Greco, R., Valenti, P. & Rotilio, G. (1998). Overexpression of a hydrogen peroxide-resistant periplasmic Cu,Zn superoxide dismutase protects Escherichia coli from macrophage killing. Biochem Biophys Res Commun 243, 804-807.
2. Bollag, D. M. & Edelstein, S. J. (1991). Immunoblotting. In Protein Methods, pp. 181-211. New York: Willey-Liss.
3. Broquist, H. P. (1971). Lysine biosynthesis (yeast). Methods Enzymol 17, 112-129.
4. 2-dependent methionine auxotrophy in Cu,Zn superoxide dismutase-deficient mutants of Saccharomyces cerevisiae. J Bacteriol 172, 1840-1845.
5. Chary, P., Dillon, D., Schroeder, A. L. & Natvig, D. O. (1994). Superoxide dismutase (sod-1) null mutants of Neurospora crassa: oxidative stress sensitivity, spontaneous mutation rate and response to mutagens. Genetics 137, 723-730.
6. Coleman, D. C., Bennett, D. E., Sullivan, D. J., Gallagher, P. J., Henman, M. C., Stanley, M. B. & Russell, R. J. (1993). Oral Candida in HIV infection and AIDS: new perspectives/new approaches. Crit Rev Microbiol 19, 61-82.
7. Culotta, V. C., Joh, H. D., Lin, S. J., Slekar, K. H. & Strain, J. (1995). A physiological role for Saccharomyces cerevisiae copper/zinc superoxide dismutase in copper buffering. J Biol Chem 270, 29991-29997.
8. Cutler, J. E. (1991). Putative virulence factors of Candida albicans. Annu Rev Microbiol 45, 187-218.
9. Diez, B., Schleissner, C., Moreno, M. A., Rodriguez, M., Collados, A. & Barredo, J. L. (1998). The manganese superoxide dismutase from the penicillin producer Penicillium chrysogenum. Curr Genet 33, 387-394.
10. Farrant, J. L, Sansone, A., Canvin, J. R., Pallen, M. J., Langford, P. R., Wallis, T. S., Dougan, G. & Kroll, J. S. (1997). Bacterial copper- and zinc-cofactored superoxide dismutase contributes to the pathogenesis of systemic salmonellosis. Mol Microbiol 25, 785-796.
11. Fonzi, W. A. & Irwin, M. Y. (1993). Isogenic strain construction and gene mapping in Candida albicans. Genetics 134, 717-728.
12. Fridovich, I. (1989). Superoxide dismutases. An adaptation to a paramagnetic gas. J Biol Chem 264, 7761-7764.
13. Fridovich, I. (1995). Superoxide radical and superoxide dismutases. Annu Rev Biochem 64, 97-112.
14. Gunasekaran, U., Yang, R. & Gunasekaran, M. (1998). Regulation of superoxide dismutase synthesis in Candida albicans. Mycopathologia 141, 59-63.
15. Hamilton, A. J. & Holdom, M. D. (1999). Antioxidant systems in the pathogenic fungi of man and their role in virulence. Med Mycol 37, 375-389.
16. Hong, Z., LoVerde, P. T., Hammarskjöld, M. L. & Rekosh, D. (1992). Schistosoma mansoni: cloning of a complementary DNA encoding cytosolic Cu/Zn superoxide dismutase and high-yield expression of the enzymatically active gene product in Escherichia coli. Exp Parasitol 75, 308-322.
17. Huh, W.-K., Kim, S.-T., Kim, H., Jeong, G. & Kang, S.-O. (2001). Deficiency of D-erythroascorbic acid attenuates hyphal growth and virulence of Candida albicans. Infect Immun 69, 3939-3946.
18. Hwang, C.-S., Rhie, G.-e., Kim, S.-T., Kim, Y.-R., Huh, W.-K., Baek, Y.-U. & Kang, S.-O. (1999). Copper- and zinc-containing superoxide dismutase and its gene from Candida albicans. Biochem Biophys Acta 1427, 245-255.
19. Izawa, S., Inoue, Y. & Kimura, A. (1995). Oxidative stress response in yeast: effect of glutathione on adaptation to hydrogen peroxide stress in Saccharomyces cerevisiae. FEBS Lett 368, 73-76.
20. Jamieson, D. J., Stephen, D. W. S. & Terriere, E. C. (1996). Analysis of the adaptive oxidative stress response of Candida albicans. FEMS Microbiol Lett 138, 83-88.
21. Kitayama, M. & Togasaki, R. K. (1995). Purification and cDNA isolation of chloroplastic phosphoglycerate kinase from Chlamydomonas reinhardtii. Plant Physiol 107, 393-400.
22. Lamarre, C., LeMay, J. D., Deslauriers, N. & Bourbonnais, Y. (2001). Candida albicans expresses an unusual cytoplasmic manganese-containing superoxide dismutase (SOD3 gene product) upon the entry and during the stationary phase. J Biol Chem 276, 43784-43791.
23. Lee, K. L., Buckley, H. R. & Campbell, C. C. (1975). An amino acid liquid synthetic medium for the development of mycelial and yeast forms of Candida albicans. Sabouraudia 13, 148-153.
24. Liu, H., Köhler, J. & Fink, G. R. (1994). Suppression of hyphal formation in Candida albicans by mutation of a STE12 homolog. Science 266, 1723-1725.
25. Liu, X. F., Elashvili, I., Gralla, E. B., Valentine, J. S., Lapinskas, P. & Culotta, V. C. (1992). Yeast lacking superoxide dismutase. Isolation of genetic suppressors. J Biol Chem 267, 18298-18302.
26. Lo, H. J., Köhler, J. R., DiDomenico, B., Loebenberg, D., Cacciapuoti, A. & Fink, G. R. (1997). Nonfilamentous C. albicans mutants are avirulent. Cell 90, 939-949.
27. Manchenko, G. P. (1994). Superoxide dismutase. In Handbook of Detection of Enzymes on Electrophoretic Gels, p. 98. Boca Raton, FL: CRC.
28. Okado-Matsumoto, A. & Fridovich, I. (2001). Subcellular distribution of superoxide dismutases (SOD) in rat liver: Cu, Zn-SOD in mitochondria. J Biol Chem 276, 38388-38393.
29. Rhie, G.-e., Hwang, C.-S., Brady, M. J. & 7 other authors (1999). Manganese-containing superoxide dismutase and its gene from Candida albicans. Biochim Biophys Acta 1426, 409-419.
30. Rocha, C. R., Schroppel, K., Harcus, D., Marcil, A., Dignard, D., Taylor, B. N., Thomas, D. Y., Whiteway, M. & Leberer, E. (2001). Signaling through adenylyl cyclase is essential for hyphal growth and virulence in the pathogenic fungus Candida albicans. Mol Biol Cell 12, 3631-3643.
31. Sambrook, J., Fritsch, E. F. & Maniatis, T. (1989). Molecular Cloning: a Laboratory Manual, 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
32. Vázquez-Torres, A. & Balish, E. (1997). Macrophages in resistance to candidiasis. Microbiol Mol Biol Rev 61, 170-192.
33. Wagner, D. K., Collins-Lech, C. & Sohnle, P. G. (1986). Inhibition of neutrophil killing of Candida albicans pseudohyphae by substances which quench hypochlorous acid and chloramines. Infect Immun 51, 731-735.
34. Wilks, K. E., Dunn, K. L. R., Farrant, J. L., Reddin, K. M., Gorringe, A. R., Langford, P. R. & Kroll, J. S. (1998). Periplasmic superoxide dismutase in meningococcal pathogenicity. Infect Immun 66, 213-217.
35. Wysong, D. R., Christin, L., Sugar, A. M., Robbins, P. W. & Diamond, R. D. (1998). Cloning and sequencing of a Candida albicans catalase gene and effects of disruption of this gene. Infect Immun 66, 1953-1961.
36. Youn, H.-D., Kim, E.-J., Roe, J.-H., Hah, Y. C. & Kang, S.-O. (1996a). A novel nickel-containing superoxide dismutase from Streptomyces spp. Biochem J 318, 889-896.
37. Youn, H.-D., Youn, H., Lee, J.-W., Yim, Y.-I., Lee, J.-K., Hah, Y. C. & Kang, S.-O. (1996b). Unique isozymes of superoxide dismutase in Streptomyces griseus. Arch Biochem Biophys 334, 341-348.