Deficiency of D-erythroascorbic acid attenuates hyphal growth and virulence of Candida albicans

Infection and Immunity

Volumn 69, Issue 6, 2001, Pages 3939-3946

  Huh, W K ^a   Kim, S T ^a   Kim, H ^a   Jeong, G ^a   Kang, S O ^a  

^a Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ASCORBIC ACID DERIVATIVE; DEXTRO ERYTHROASCORBIC ACID; OXIDOREDUCTASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; ASCORBIC ACID DEFICIENCY; CANDIDA ALBICANS; ENZYME ACTIVITY; FEMALE; FUNGUS HYPHAE; GENE; GENE DISRUPTION; GENE EXPRESSION; MOUSE; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; OXIDATIVE STRESS; PRIORITY JOURNAL; VIRULENCE;

AMINO ACID SEQUENCE; ANIMALS; ASCORBIC ACID; CANDIDA ALBICANS; CANDIDIASIS; CLONING, MOLECULAR; FEMALE; GENE DELETION; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; OXIDATIVE STRESS; SEQUENCE ANALYSIS, DNA; SUGAR ALCOHOL DEHYDROGENASES; VIRULENCE;

EID: 0035016183     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.69.6.3939-3946.2001     Document Type: Article

References (40)

1. Missing step in man, monkey and guinea pig required for the biosynthesis of L-ascorbic acid
2. Cloning and expression of Candida albicans ADE2 and proteinase genes on a replicative plasmid in C. albicans and in Saccharomyces cerevisiae
3. Evolution and the biosynthesis of ascorbic acid
4. Putative virulence factors of Candida albicans
5. Control of nucleotide and erythroascorbic acid pools by cyclic AMP in Neurospora crassa
6. Isogenic strain construction and gene mapping in Candida albicans
7. A novel oxidoreductase family sharing a conserved FAD-binding domain
8. Linkage of adhesion, filamentous growth, and virulence in Candida albicans to a single gene, INT1
9. Characterisation of D-arabinono-1,4-lactone oxidase from Candida albicans ATCC 10231
10. D-erythroascorbic acid is an important antioxidant molecule in Saccharomyces cerevisiae
11. L-galactono-γ-lactone dehydrogenase from sweet potato: Purification and cDNA sequence analysis
12. Identification of the covalently-bound flavin of L-galactonolactone oxidase from yeast
13. D-arabinose dehydrogenase and biosynthesis of erythroascorbic acid in Candida albicans
14. D-arabinose dehydrogenase and its gene from Saccharomyces cerevisiae
15. Purification and characterization of L-gulonolactone oxidase from chicken kidney microsomes
16. Candida albicans strains heterozygous and homozygous for mutations in mitogen-activated protein kinase signaling components have defects in hyphal development
17. Isolation and sequence analysis of a complementary DNA encoding rat liver L-gulono-γ-lactone oxidase, a key enzyme for L-ascorbic acid biosynthesis
18. A simple method for displaying the hydropathic character of a protein
19. Signal transduction through homologs of the Ste20p and Ste7p protein kinases can trigger hyphal formation in the pathogenic fungus Candida albicans
20. Bacterial production of D-erythroascorbic acid and L-ascorbic acid through functional expression of Saccharomyces cerevisiae D-arabinono-1,4-lactone oxidase in Escherichia coli
21. An amino acid liquid synthetic medium for the development of mycelial and yeast forms of Candida albicans
22. Suppression of hyphal formation in Candida albicans by mutation of a STE12 homolog
23. Nonfilamentous C. albicans mutants are avirulent
24. Conversion of D-arabinose to D-erythroascorbic acid and oxalic acid in Sclerotinia sclerotiorum
25. Biological synthesis of ascorbic acid; L-galactono-γ-lactone dehydrogenase
26. Vitamin C
27. Biosynthesis of D-erythroascorbic acid by Candida
28. Isolation and identification of erythroascorbic acid in Saccharomyces cerevisiae and Lypomyces starkeyi
29. Purification and characterization of L-gulono-γ-lactone oxidase from rat and goat liver
30. Purification and properties of L-galactono-γ-lactone dehydrogenase, a key enzyme for ascorbic acid biosynthesis, from sweet potato roots
31. Isolation of a cDNA coding for L-galactono-γ-lactone dehydrogenase, an enzyme involved in the biosynthesis of ascorbic acid in plants
32. The CUG codon is decoded in vivo as serine and not leucine in Candida albicans
33. Synthesis and properties of D-erythroascorbic acid and its vitamin C activity in the tobacco hornworm (Manduca sexta)
34. Getting started with yeast
35. Adhesive and mammalian transglutaminase substrate properties of Candida albicans Hwpl
36. Efglp, an essential regulator of morphogenesis of the human pathogen Candida albicans, is a member of a conserved class of bHLH proteins regulating morphogenetic processes in fungi
37. Macrophages in resistance to candidiasis
38. Inhibition of neutrophil killing of Candida albicans pseudohyphae by substances which quench hypochlorous acid and chloramines
39. The biosynthetic pathway of vitamin C in higher plants
40. Cloning and sequencing of a Candida albicans catalase gene and effects of disruption of this gene