5-Year results of pulsed dose rate brachytherapy applied as a boost after breast-conserving therapy in patients at high risk for local recurrence from breast cancer

Strahlentherapie und Onkologie

Volumn 178, Issue 11, 2002, Pages 607-614

  Harms, Wolfgang ^a   Krempien, Robert ^a   Hensley, Frank W ^a   Berns, Christiane ^a   Fritz, Peter ^b   Wannenmacher, Michael ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b St Marien Krankenhaus Siegen gem GmbH   (Germany)

Author keywords

Boost; Breast cancer; Cosmesis; High risk of local recurrence; Low dose rate brachytherapy; Pulsed dose rate brachytherapy; Radiotherapy

Indexed keywords

IRIDIUM 192;

ADULT; AGED; ARTICLE; BRACHYTHERAPY; BREAST CANCER; CANCER INVASION; CANCER STAGING; CONTROLLED STUDY; ESTHETICS; FEMALE; FIBROSIS; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; PARTIAL MASTECTOMY; PROSPECTIVE STUDY; RADIATION DOSE; RECURRENT CANCER; SKIN TOXICITY; SURVIVAL RATE; SURVIVAL TIME; TELANGIECTASIA; TREATMENT FAILURE; TREATMENT PLANNING;

ADULT; AGED; BRACHYTHERAPY; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CARCINOMA, LOBULAR; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; DOSE FRACTIONATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; MASTECTOMY, SEGMENTAL; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; RADIOTHERAPY, ADJUVANT; RISK;

EID: 0036854232     PISSN: 01797158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00066-002-0977-9     Document Type: Article

References (56)

1. Anscher MS, Jones P, Prosnitz LR, et al. Local failure and margin status in early stage breast carcinoma treated with conservation surgery and radiation therapy. Ann Surg 1993;218:22-8.
2. Bartelink H, Horiot JC, Poortmans P, et al. Recurrence rates after treatment of breast cancer with standard radiotherapy with or without additional radiation. N Engl J Med 2001;345:1378-87.
3. Berns C, Fritz P, Hensley FW, Wannenmacher M. Consequences of optimization in PDR brachytherapy - Is a routine geometrical optimization recommendable? Int J Radiat Oncol Biol Phys 1997;37:1171-80.
4. Borger J, Kempermann H, Hart A, et al. Risk factors in breast-conservation therapy. J Clin Oncol 1994;12:653-60.
5. Brenner DJ, Hall EJ. Conditions for the equivalence of continuous to pulsed low dose rate brachytherapy. Int J Radiat Oncol Biol Phys 1991;20:181-90.
6. Clarke BH, Lé MG, Sarrazin D, et al. Analysis of local-regional relapses in patients with early stage breast cancer treated by excision and radiotherapy: Experience of the Institue Gustave-Roussy. Int J Radiat Oncol Biol Phys 1985;11:137-45.
7. Cowen D, Houvenaeghel G, Bardou V-J, et al. Local and distant failures after limited surgery with positive margins and radiotherapy for node-negative breast cancer. Int J Radiat Oncol Biol Phys 2000;47:305-12.
8. De Pree C, Popowski Y, Weber D, Nouet P, Pouzard M, Kurtz JM. Feasibility and tolerance of pulsed dose rate interstitial brachytherapy. Int J Radiat Oncol Biol Phys 1999;43:971-6.
9. DeBiose DA, Horwitz EM, Martinez AA, et al. The use of ultrasonography in the localization of the lumpectomy cavity for interstitial brachytherapy of the breast. Int J Radiat Oncol Biol Phys 1997;38:755-9.
10. Deore SM, Sarin R, Dinshaw KA, Shrivastana SK. Influence of dose-rate and dose per fraction on clinical outcome of breast cancer treated by external beam irradiation plus iridium-192 implants: Analysis of 289 cases. Int J Radiat Oncol Biol Phys 1993,26:601-6.
11. Edmundson GK. Geometry based optimization for stepping source implants. In: Martinez AA, Orton CG, Mould RF, eds. Brachytherapy HDR and LDR. Columbia, MD: Nucletron, 1990:184-92.
12. Fortin A, Larochelle M, Laverdière, Lavertu S, Tremblay D. Local failure is responsible for the decrease in survival for patients with breast cancer treated with conservative surgery and postoperative radiotherapy. J Clin Oncol 1999;17:101-9.
13. Fourquet A, Campana F, Zafrani B, et al. Prognostic factors of breast recurrence in the conservative management of early breast cancer: A 25-year follow-up. Int J Radiat Oncol Biol Phys 1989;17:719-25.
14. Fowler J, Mount M. Pulsed brachytherapy: The conditions for no significant loss of therapeutic ratio compared with traditional low dose rate brachytherapy. Int J Radiat Oncol Biol Phys 1992;23:661-9.
15. Fowler JF, Van Limbergen EFM. Biological effect of pulsed dose rate brachytherapy with stepping sources if short half-times of repair are present in tissues. Int J Radiat Oncol Biol Phys 1997;37:877-83.
16. Fritz P, Berns C, Anton HW, et al. PDR brachytherapy with flexible implants for interstitial boost after breast-conserving surgery and external beam radiation therapy. Radiother Oncol 1997;45:23-32.
17. Gage I, Recht A, Gelman R, et al. Long-term outcome following breast conserving surgery and radiation therapy. Int J Radiat Oncol Biol Phys 1995;33:245-51.
18. Hammer J, Mazeron JJ, Van Limbergen E. Breast boost - Why, how, when ...? Strahlenther Onkol 1999;175:478-83.
19. Hammer J, Seewald DH, Track C, et al. Breast cancer: Primary treatment with external-beam radiation therapy and high-dose-rate iridium implantation. Radiology 1994;193:573-7.
20. Hammer J, Van Limbergen E, Mazeron JJ. Statements of the GEC-ESTRO Consenus Meeting on Breast Cancer: "To Boost or not to Boost and How to Do It." (In preparation, personal communication.)
21. Harms W, Krempien R, Hensley FW, Berns C, Wannenmacher M, Fritz P. Results of chest wall reirradiation using pulsed dose rate [PDR] brachytherapy moulds for breast cancer local recurrences. Int J Radiat Oncol Biol Phys 2001;49:205-10.
22. Hennequin C, Durdux C, Espie M, et al. High-dose-rate brachytherapy for early breast cancer: An ambulatory technique. Int J Radiat Oncol Biol Phys 1999;45:85-90.
23. Jacobs H. Experiences with interstitial HDR aftertoading therapy in genital and breast cancer. Strahlenther Onkol 1988;82:Sonderbd:266-70.
24. Jacobsen JA, Danfoth DN, Cowan K, et al. Ten-year results of a comparison of conservation with mastectomy in the treatment of stage I and II breast cancer. N Engl J Med 1995;332:907-11.
25. Kaplan EL, Meier P. Nonparametric estimation from incomptete observations. J Am Stat Ass 1958;53:457-82.
26. Kurtz JM. Which patients don't need a tumor-bed boost after whole-breast radiotherapy? Strahlenther Onkol 2001;177:33-6.
27. Mangold CA, Rijnders A, Georg D, Van Limbergen E, Pötter R, Huyskens D. Quality control in interstitial brachytherapy of the breast using pulsed dose rate: Treatment planning and dose delivery with an Ir-192 after loading system. Radiother Oncol 2001;58:43-51.
28. Manning M, Arthur DW, Schmidt-Ullrich RK, et al. Interstitial high-dose-rate brachytherapy boost: The feasibility and cosmetic outcome of a fractionated outpatient delivery scheme. Int J Radiat Oncol Biol Phys 2000;48:1301-6.
29. Mansfield CM, Kormanicky LT, Schwartz GF, et al. Ten-year results in 1070 patients with stages I and II breast cancer treated by conservative surgery and radiation therapy. Cancer 1995;75:2328-36.
30. McRae D, Rodgers J, Dritschilo A. Dose-volume and complication in interstitial implants for breast carcinoma. Int J Radiat Oncol Biol Phys 1987; 13:525-9.
31. Moreno F, Gueda F, Lopez Y, et al. External beam irradiation plus 192 Ir implant after breast-preserving surgery in women with early breast cancer. Int J Radiat Oncol Biol Phys 2000;48:757-65.
32. Olivotto IA, Rose MA, Osteen RT, et al. Late cosmetic outcome after conservative surgery and radiotherapy: Analysis of causes of cosmetic failure. Int J Radiat Oncol Biol Phys 1989;17:747-53.
33. Ott O, Strnad V. Only interstitial brachytherapy of the tumor bed as an alternative to teletherapy in selected breast cancer patients. Strahlenther Onkol 2001;177:558-9.
34. Perez CA, Taylor ME, Halverson K, Garcia D, Kuske RR, Locket MA. Brachytherapy or electron beam boost in conservation therapy of carcinoma of the breast: A nonrandomized comparison. Int J Radiat Oncol Biol Phys 1996;34:995-1007.
35. Perez CA, Taylor ME. Breast: stage Tis, T1, and T2 tumors. In: Perez CA, Brady LW, eds. Principles and Practice of Radiation Oncology, 3rd Ed. Philadelphia: Lipincott, 1997:1269-1414.
36. Peterson ME, Schultz DJ, Reynolds C, et al. Outcomes in breast cancer patients relative to margin status after treatment with breast conserving surgery and radiation therapy: The University of Pennsylvania experience. Int J Radiat Oncol Biol Phys 1999;43:1029-35.
37. Pizzi GB, Marchetti C. Brachytherapy with pulsed dosage. General considerations. Radiobiological considerations. First clinical experience in Mestre (Venice). Radiol Med 1997;93:260-6.
38. Polgar C, Major T, Somogyi A, et al. Sole brachytherapy of the tumor bed after breast conserving surgery: A new radiotherapeutic strategy for patients at low risk of local relapse. Neoplasma 1999;46:182-9.
39. Polgar C, Major T, Somogyi A, et al. CT-image-based conformal brachytherapy of breast cancer. The significance of semi-3-D and 3-D treatment ptanning. Strahlenther Onkol 2000;176:118-24.
40. Puthawala AA, Syed AMN, Sheikh KMA, Gowdy RA, McNamara CS. Combined external and interstitial irradiation in the treatment of stage III breast cancer. Radiology 1984;153:813-6.
41. Rabinovitch R, Finlayson C, Pan Z, et al. Radiographic evaluation of surgical clips is better than ultrasound for defining the lumpectomy cavity in breast boost treatment planning: A prospective clinical study. Int J Radiat Oncol. Biol. Phys 2000;47:313-7.
42. Roed H, Engelholm SA, Svendsen LB, Rosendal F, Olsen KJ. Pulsed dose rate (PDR) brachytherapy of anal carcinoma. Radiother Oncol. 1996;41:131-4.
43. Rogers LC, Freel JH, Speiser BL. Pulsed dose rate brachytherapy for uterine cervix carcinoma. Int J Radiat Oncol Biol Phys 1999;43:95-100.
44. Romestaing P, Lehingue Y, Carrie C, et al. Role of a 10-Gy boost in the conservative treatment of early breast cancer: Results of a randomized clinical trail in Lyon, France. J Clin Oncol 1997;15:963-8.
45. Schmoor C, Sauerbrei W, Bastert G, Schumacher M. Role of isolated locoregional recurrence of breast cancer: Results of four prospective studies. J Clin Oncol 2000;18:1696-1708.
46. Sedlmayer F, Rahim HBK, Kogelnik HD, et al. Quality assurance in breast cancer brachytherapy: Geographic miss in the interstitial boost treatment of the tumor bed. Int J Radiat Oncol Biol Phys 1996;34:1133-9.
47. Seegenschmiedt MH, Sauer R. Systematik der akuten und chronischen Strahlenfolgen Strahlenther Onkol 1993;169:83-95.
48. Smitt MC, Nowets KW, Zdeblick MJ, et al. The importance of the lumpectomy surgical margin status in long-term results of breast conservation. Cancer 1995;76:259-67.
49. Strnad V, Lotter M, Grabenbauer G, Sauer R. Early results of pulsed-doserate interstitiat brachytherapy for head and neck malignancies after limited surgery. Int J Radiat Oncol Biol Phys 2000;46:27-30.
50. Taylor ME, Perez CA, Halverson KJ, et al. Factors influencing cosmetic resuits after conservation therapy for breast cancer. Int J Radiat Oncol. Biol. Phys 1995;31:753-64.
51. UICC, International Union Against Cancer. TNM Klassifikation Maligner Tumoren, 5. Aufl. Berlin-Heidelberg-New York: Springer, 1997:119-26.
52. Veronesi U, Banfi A, Salvadori B, et al. Breast conservation is the treatment of choice in small breast cancer: Long-term results of a randomized trail. Eur J Cancer 1990;26:668-70.
53. Vicini FA, Horwitz EM, Lacerna MD, et at. Long-term outcome with interstitial brachytherapy in the management of patients with early stage breast cancer treated with breast conserving therapy. Int J Radiat Oncol Biol Phys 1997;37:845-52.
54. Voogd AC, Nielsen M, Peterse JL, et al. Differences in risk factors for local and distant recurrence after breast-conserving therapy or mastectomy for stage I and II breast cancer: Pooled results of two large european randomized trials. J Clin Oncol 2001;19:1688-97.
55. Wazer DE, DiPetrillo T, Schmidt-Ullrich R, et al. Factors influencing cosmetic outcome and complication risk after conservative surgery and radiotherapy for early-stage breast carcinoma. J Clin Oncol 1992;10:356-63.
56. Wazer DE, Lowther D, Boyle T, et al. Clinically evident fat necrosis in women treated with high-dose-rate brachytherapy alone for early stage breast cancer. Int J Radiat Oncol Biol Phys 2001;50:107-111.