Glycosylation processing inhibition by castanospermine prevents experimental autoimmune encephalomyelitis by interference with IL-2 receptor signal transduction

Journal of Neuroimmunology

Volumn 132, Issue 1-2, 2002, Pages 1-10

  Walter, Silke ^a   Fassbender, Klaus ^a   Gulbins, Erich ^b   Liu, Yang ^a   Rieschel, Monika ^c,d   Herten, Monika ^e   Bertsch, Thomas ^f   Engelhardt, Britta ^d  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^d MAX PLANCK INSTITUTE FOR MOLECULAR BIOMEDICINE   (Germany)

^e HEINRICH HEINE UNIVERSITY   (Germany)

^f UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

EAE; Glycosylation; Interleukin 2 receptor; Multiple sclerosis; Signal transduction

Indexed keywords

CASTANOSPERMINE; GLYCOPROTEIN; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CELL ASSAY; CELL MATURATION; CELL MIGRATION; CLINICAL FEATURE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG TARGETING; ENDOTHELIUM; FLUORESCENCE ACTIVATED CELL SORTING; GLYCOSYLATION; IMMUNOREGULATION; LYMPHOCYTIC INFILTRATION; MOUSE; MULTIPLE SCLEROSIS; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR BINDING; SIGNAL TRANSDUCTION; T LYMPHOCYTE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; CELL ADHESION; CELL MOVEMENT; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; FEMALE; GLYCOSYLATION; INDOLIZINES; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; MICE; RECEPTORS, INTERLEUKIN-2; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 0036850475     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(02)00308-9     Document Type: Article

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