Functional imaging of single synapses in brain slices

Experimental Physiology

Volumn 87, Issue 6, 2002, Pages 733-736

  Oertner, Thomas G ^a  

^a Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; FLUORESCENT DYE;

ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DENDRITIC SPINE; FLUORESCENCE; IMAGE DISPLAY; IMAGE SUBTRACTION; IMAGING SYSTEM; INTERMETHOD COMPARISON; MICROSCOPE IMAGE; MICROSCOPY; NONHUMAN; QUANTITATIVE ASSAY; RAT; SYNAPTIC TRANSMISSION; TISSUE SLICE; TWO PHOTON MICROSCOPY; ANIMAL; BRAIN; CHEMISTRY; COMPARATIVE STUDY; HUMAN; INSTRUMENTATION; METHODOLOGY; MULTIPHOTON MICROSCOPY; PHYSIOLOGY; REVIEW; SYNAPSE;

ANIMALS; BRAIN; HUMANS; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; SYNAPSES;

EID: 0036848473     PISSN: 09580670     EISSN: None     Source Type: Journal    
DOI: 10.1113/eph8702482     Document Type: Article

References (14)

1. BERGLES, D. E., DIAMOND, J. S. & JAHR, C. E. (1999). Clearance of glutamate inside the synapse and beyond. Current Opinion in Neurobiology 9, 293-298.
2. DENK, W., PISTON, D. W. & WEBB, W. W. (1995). Two-photon molecular excitation in laser-scanning microscopy. In Handbook of Biological Confocal Microscopy, ed. Pawley, J. B., pp. 445-458. Plenum Press, New York.
3. DENK, W. & SVOBODA, K. (1997). Photon upmanship: why multiphoton imaging is more than a gimmick. Neuron 18, 351-357.
4. DENK, W., YUSTE, R., SVOBODA, K. & TANK, D. W. (1996). Imaging calcium dynamics in dendritic spines. Current Opinion in Neurobiology 6, 372-378.
5. 2+ indicators with greatly improved fluorescence properties. Journal of Biological Chemistry 260, 3440-3450.
6. 2+ signaling in dendrites of pyramidal neurons. Biophysical Journal 70, 1069-1081.
7. 2+-permeable AMPA receptors in Bergmann glia. Science 292, 926-929.
8. MAINEN, Z. F., MALETIC-SAVATIC, M., SHI, S. H., HAYASHI, Y., MALINOW, R. & SVOBODA, K. (1999a). Two-photon imaging in living brain slices. Methods 18, 231-239.
9. MAINEN, Z. F., MALINOW, R. & SVOBODA, K. (1999b). Synaptic calcium transients in single spines indicate that NMDA receptors are not saturated. Nature 399, 151-155.
10. MARKRAM, H., WANG, Y. & TSODYKS, M. (1998). Differential signaling via the same axon of neocortical pyramidal neurons. Proceedings of the National Academy of Sciences of the USA 95, 5323-5328.
11. NEHER, E. & AUGUSTINE, G. J. (1992). Calcium gradients and buffers in bovine chromaffin cells. Journal of Physiology 450, 273-301.
12. OERTNER, T. G., SABATINI, B. L., NIMCHINSKY, E. A. & SVOBODA, K. (2002). Facilitation at single synapses probed with optical quantal analysis. Nature Neuroscience 5, 657-664.
13. 2+ ions in dendritic spines. Neuron 33, 439-452.
14. TSAI, P. S., NISHIMURA, N., YODER, E. J., WHITE, A., DOLNICK, E. & KLEINFELD, D. (2002). Principles, design and construction of a two photon scanning microscope for in vitro and in vivo studies. In Methods for In Vivo Optical Imaging, ed. FROSTIG, R., pp. 113-171. CRC Press, New York.