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Volumn 24, Issue 3, 2002, Pages 236-244

Clinical significance of the changes of platelet counts and serum thrombopoietin levels in chronic hepatitis C patients treated with different doses of consensus interferon

Author keywords

Chronic hepatitis C; Consensus interferon; Thrombocytopenia; Thrombopoietin

Indexed keywords

ALPHA INTERFERON; ALPHA2A INTERFERON; ALPHA2B INTERFERON; CONSENSUS INTERFERON; PLACEBO; THROMBOPOIETIN; VIRUS RNA;

EID: 0036847382     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1386-6346(02)00108-0     Document Type: Article
Times cited : (9)

References (39)
  • 1
    • 8944258119 scopus 로고    scopus 로고
    • A sensitive sandwich ELISA for measuring thrombopoietin in human serum: Serum thrombopoietin levels in healthy volunteers and in patients with haemopoietic disorders
    • Tahara T, Usuki K, Sato H, et al. A sensitive sandwich ELISA for measuring thrombopoietin in human serum: serum thrombopoietin levels in healthy volunteers and in patients with haemopoietic disorders. Br J Haematol 1996;93:783-8.
    • (1996) Br. J. Haematol , vol.93 , pp. 783-788
    • Tahara, T.1    Usuki, K.2    Sato, H.3
  • 2
    • 0029835344 scopus 로고    scopus 로고
    • Constitutive expression of Mpl ligand transcripts during thrombocytopenia or thrombocytosis
    • Cohen-Solal K, Villeval JL, Titeux M, Lok S, Vainchenker W, Wendling F. Constitutive expression of Mpl ligand transcripts during thrombocytopenia or thrombocytosis. Blood 1996;88:2578-84.
    • (1996) Blood , vol.88 , pp. 2578-2584
    • Cohen-Solal, K.1    Villeval, J.L.2    Titeux, M.3    Lok, S.4    Vainchenker, W.5    Wendling, F.6
  • 3
    • 0031052063 scopus 로고    scopus 로고
    • Thrombopoietin: The primary regulator of megakaryocytopoiesis and thrombopoiesis
    • Eaton DL, de Sauvage FJ. Thrombopoietin: the primary regulator of megakaryocytopoiesis and thrombopoiesis. Exp Hematol 1997;25:1-7.
    • (1997) Exp. Hematol , vol.25 , pp. 1-7
    • Eaton, D.L.1    de Sauvage, F.J.2
  • 4
    • 0031035555 scopus 로고    scopus 로고
    • Localization and regulation of thrombopoietin mRNA expression in human kidney, liver, bone marrow and spleen using in situ hybridization
    • Sungaran R, Markovic B, Chong BH. Localization and regulation of thrombopoietin mRNA expression in human kidney, liver, bone marrow and spleen using in situ hybridization. Blood 1997;89:101-7.
    • (1997) Blood , vol.89 , pp. 101-107
    • Sungaran, R.1    Markovic, B.2    Chong, B.H.3
  • 6
    • 0028302409 scopus 로고
    • Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand
    • de Sauvage FJ, Hass PE, Spencer SD, et al. Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand. Nature 1994;369:533-8.
    • (1994) Nature , vol.369 , pp. 533-538
    • de Sauvage, F.J.1    Hass, P.E.2    Spencer, S.D.3
  • 7
    • 0030048887 scopus 로고    scopus 로고
    • Thrombopoietin in thrombocytopenic mice: Evidence against regulation at the mRNA level and for a direct regulatory role of platelets
    • Stoffel R, Wiestner A, Skoda RC. Thrombopoietin in thrombocytopenic mice: evidence against regulation at the mRNA level and for a direct regulatory role of platelets. Blood 1996;87:567-73.
    • (1996) Blood , vol.87 , pp. 567-573
    • Stoffel, R.1    Wiestner, A.2    Skoda, R.C.3
  • 8
    • 0011274073 scopus 로고    scopus 로고
    • Human thrombopoietin levels are high when thrombocytopenia is due to increased platelet destruction
    • Emmons RV, Reid DM, Cohen RL, et al. Human thrombopoietin levels are high when thrombocytopenia is due to increased platelet destruction. Blood 1996;87:1896-904.
    • (1996) Blood , vol.87 , pp. 1896-1904
    • Emmons, R.V.1    Reid, D.M.2    Cohen, R.L.3
  • 11
  • 12
    • 0027081704 scopus 로고
    • Long-term follow-up of non-A, non-B (type C) post-transfusion hepatitis
    • Tremolada F, Casarin C, Alberti A, et al. Long-term follow-up of non-A, non-B (type C) post-transfusion hepatitis. J Hepatol 1992;16:273-81.
    • (1992) J. Hepatol , vol.16 , pp. 273-281
    • Tremolada, F.1    Casarin, C.2    Alberti, A.3
  • 13
    • 10344229413 scopus 로고    scopus 로고
    • Serum thrombopoietin (c-Mpl ligand) levels in patients with liver cirrhosis
    • Shimodaira S, Ishida F, Ichikawa N, et al. Serum thrombopoietin (c-Mpl ligand) levels in patients with liver cirrhosis. Thromb Haemostasis 1996;76:545-8.
    • (1996) Thromb. Haemostasis , vol.76 , pp. 545-548
    • Shimodaira, S.1    Ishida, F.2    Ichikawa, N.3
  • 14
    • 0030753987 scopus 로고    scopus 로고
    • Cellular localization of thrombopoietin mRNA in the liver by in situ hybridization
    • Nomura S, Ogami K, Kawamura K, et al. Cellular localization of thrombopoietin mRNA in the liver by in situ hybridization. Exp Hematol 1997;25:565-72.
    • (1997) Exp. Hematol , vol.25 , pp. 565-572
    • Nomura, S.1    Ogami, K.2    Kawamura, K.3
  • 16
    • 0029054011 scopus 로고
    • A comparison of three interferon alfa-2b regimens for the long-term treatment of chronic non-A, non-B hepatitis
    • Multicenter Study Group
    • Poynard T, Bedossa P, Chevallier M, et al. A comparison of three interferon alfa-2b regimens for the long-term treatment of chronic non-A, non-B hepatitis. Multicenter Study Group. N Engl J Med 1995;332:1457-62.
    • (1995) N. Engl. J. Med , vol.332 , pp. 1457-1462
    • Poynard, T.1    Bedossa, P.2    Chevallier, M.3
  • 17
    • 0027378724 scopus 로고
    • Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B. A meta-analysis
    • Wong DK, Cheung AM, O'Rourke K, Naylor CD, Detsky AS, Heathcote J. Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B. A meta-analysis. Ann Intern Med 1993;119:312-23.
    • (1993) Ann. Intern. Med , vol.119 , pp. 312-323
    • Wong, D.K.1    Cheung, A.M.2    O'Rourke, K.3    Naylor, C.D.4    Detsky, A.S.5    Heathcote, J.6
  • 19
    • 0030737715 scopus 로고    scopus 로고
    • Is inadequate thrombopoietin production a major cause of thrombocytopenia in cirrhosis of the liver?
    • Peck-Radosavljevic M, Zacherl J, Meng YG, et al. Is inadequate thrombopoietin production a major cause of thrombocytopenia in cirrhosis of the liver? J Hepatol 1997;27:127-31.
    • (1997) J. Hepatol , vol.27 , pp. 127-131
    • Peck-Radosavljevic, M.1    Zacherl, J.2    Meng, Y.G.3
  • 20
    • 0031720994 scopus 로고    scopus 로고
    • Reduced expression of thrombopoietin is involved in thrombocytopenia in human and rat liver cirrhosis
    • Ishikawa T, Ichida T, Matsuda Y, et al. Reduced expression of thrombopoietin is involved in thrombocytopenia in human and rat liver cirrhosis. J Gastroenterol Hepatol 1998;13:907-13.
    • (1998) J. Gastroenterol. Hepatol , vol.13 , pp. 907-913
    • Ishikawa, T.1    Ichida, T.2    Matsuda, Y.3
  • 21
    • 0029121339 scopus 로고
    • Randomized controlled trial of recombinant interferon-alpha 2b in the treatment of Chinese patients with chronic hepatitis C
    • Hwang SJ, Chan CY, Lu RH, Wu JC, Lee SD. Randomized controlled trial of recombinant interferon-alpha 2b in the treatment of Chinese patients with chronic hepatitis C. J Interf Cytok Res 1995;15:611-6.
    • (1995) J. Interf. Cytok. Res , vol.15 , pp. 611-616
    • Hwang, S.J.1    Chan, C.Y.2    Lu, R.H.3    Wu, J.C.4    Lee, S.D.5
  • 22
    • 0032976179 scopus 로고    scopus 로고
    • Treatment strategies for chronic hepatitis C: Update since the 1997 National Institutes of Health Consensus Development Conference
    • Ahmed A, Keeffe EB. Treatment strategies for chronic hepatitis C: update since the 1997 National Institutes of Health Consensus Development Conference. J Gastroenterol Hepatol 1999;14(Suppl.):12-8.
    • (1999) J. Gastroenterol. Hepatol , vol.14 , Issue.SUPPL. , pp. 12-18
    • Ahmed, A.1    Keeffe, E.B.2
  • 23
    • 0027058741 scopus 로고
    • A comparison of interferon Con1 with natural recombinant interferons-alpha: Antiviral, antiproliferative, and natural killer-inducing activities
    • Ozes ON, Reiter Z, Klein S, Blatt LM, Taylor MW. A comparison of interferon Con1 with natural recombinant interferons-alpha: antiviral, antiproliferative, and natural killer-inducing activities. J Interferon Res 1992;12:55-9.
    • (1992) J. Interferon. Res , vol.12 , pp. 55-59
    • Ozes, O.N.1    Reiter, Z.2    Klein, S.3    Blatt, L.M.4    Taylor, M.W.5
  • 24
    • 0027756548 scopus 로고
    • Consensus interferon induces peak mRNA accumulation at lower concentration than interferon-a 2a
    • Klein SB, Blatt LM, Taylor MW. Consensus interferon induces peak mRNA accumulation at lower concentration than interferon-a 2a. J Interferon Res 1993;13:341-7.
    • (1993) J. Interferon. Res , vol.13 , pp. 341-347
    • Klein, S.B.1    Blatt, L.M.2    Taylor, M.W.3
  • 25
    • 0029833999 scopus 로고    scopus 로고
    • The biologic activity and molecular characterization of a novel synthetic interferon alpha species, consensus interferon
    • Blatt LM, Davis JM, Klein SB, Taylor MW. The biologic activity and molecular characterization of a novel synthetic interferon alpha species, consensus interferon. J Interferon Cytok Res 1996;16:489-99.
    • (1996) J. Interferon. Cytok. Res , vol.16 , pp. 489-499
    • Blatt, L.M.1    Davis, J.M.2    Klein, S.B.3    Taylor, M.W.4
  • 26
    • 0033198578 scopus 로고    scopus 로고
    • A randomized, double-blind, controlled trial of consensus interferon in the treatment of Chinese patients with chronic patients with chronic hepatitis C
    • Hwang SJ, Lee SD, Chan CY, Lu RH, Chang FY. A randomized, double-blind, controlled trial of consensus interferon in the treatment of Chinese patients with chronic patients with chronic hepatitis C. Am J Gastroenterol 1999;94:2496-500.
    • (1999) Am. J. Gastroenterol , vol.94 , pp. 2496-2500
    • Hwang, S.J.1    Lee, S.D.2    Chan, C.Y.3    Lu, R.H.4    Chang, F.Y.5
  • 27
    • 0028051631 scopus 로고
    • A randomized controlled trial of recombinant interferon alpha-2b in the treatment of Chinese patients with acute post-transfusion hepatitis C
    • Hwang SJ, Lee SD, Chan CY, Lu RH, Lo KJ. A randomized controlled trial of recombinant interferon alpha-2b in the treatment of Chinese patients with acute post-transfusion hepatitis C. J Hepatol 1994;21:831-6.
    • (1994) J. Hepatol , vol.21 , pp. 831-836
    • Hwang, S.J.1    Lee, S.D.2    Chan, C.Y.3    Lu, R.H.4    Lo, K.J.5
  • 28
    • 0027276247 scopus 로고
    • Significance of serum hepatitis C virus RNA levels in chronic hepatitis C
    • Lau JY, Davis GL, Kniffen J, et al. Significance of serum hepatitis C virus RNA levels in chronic hepatitis C. Lancet 1993;341:1501-4.
    • (1993) Lancet , vol.341 , pp. 1501-1504
    • Lau, J.Y.1    Davis, G.L.2    Kniffen, J.3
  • 29
    • 0026563204 scopus 로고
    • Typing hepatitis C virus by polymerase chain reaction with type-specific primers: Application to clinical surveys and tracing infectious sources
    • Okamoto H, Sugiyama Y, Okada S, et al. Typing hepatitis C virus by polymerase chain reaction with type-specific primers: application to clinical surveys and tracing infectious sources. J Gen Virol 1992;73:673-9.
    • (1992) J. Gen. Virol , vol.73 , pp. 673-679
    • Okamoto, H.1    Sugiyama, Y.2    Okada, S.3
  • 30
    • 0027385067 scopus 로고
    • Characterization of the genomic sequence of type V (or 3a) hepatitis C virus isolates and PCR primer for specific detection
    • Okamoto H, Tokita H, Sakamoto M, et al. Characterization of the genomic sequence of type V (or 3a) hepatitis C virus isolates and PCR primer for specific detection. J Gen Virol 1993;74:2385-90.
    • (1993) J. Gen. Virol , vol.74 , pp. 2385-2390
    • Okamoto, H.1    Tokita, H.2    Sakamoto, M.3
  • 31
    • 0027459488 scopus 로고
    • Sequence variability in the 5′ non-coding region of hepatitis C virus: Identification of a new virus type and restrictions on sequence diversity
    • Simmonds P, McOmish F, Yap PL, et al. Sequence variability in the 5′ non-coding region of hepatitis C virus: identification of a new virus type and restrictions on sequence diversity. J Gen Virol 1993;74:661-8.
    • (1993) J. Gen. Virol , vol.74 , pp. 661-668
    • Simmonds, P.1    McOmish, F.2    Yap, P.L.3
  • 32
    • 0019813866 scopus 로고
    • Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis
    • Knodell RG, Ishak KG, Black WC, et al. Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology 1981;1:431-5.
    • (1981) Hepatology , vol.1 , pp. 431-435
    • Knodell, R.G.1    Ishak, K.G.2    Black, W.C.3
  • 33
    • 0031782291 scopus 로고    scopus 로고
    • Relationships between serum aminotransferase levels, liver histologies and virological status in patients with chronic hepatitis C in Taiwan
    • Luo JC, Hwang SJ, Lai CR, et al. Relationships between serum aminotransferase levels, liver histologies and virological status in patients with chronic hepatitis C in Taiwan. J Gastroenterol Hepatol 1998;13:685-90.
    • (1998) J. Gastroenterol. Hepatol , vol.13 , pp. 685-690
    • Luo, J.C.1    Hwang, S.J.2    Lai, C.R.3
  • 35
    • 0030818789 scopus 로고    scopus 로고
    • Thrombopoietin levels in patients with cirrhosis before and after orthotopic liver transplantation
    • Martin TG, 3rd, Somberg KA, Meng YG, et al. Thrombopoietin levels in patients with cirrhosis before and after orthotopic liver transplantation. Ann Intern Med 1997;127:285-8.
    • (1997) Ann. Intern. Med , vol.127 , pp. 285-288
    • Martin T.G. III1    Somberg, K.A.2    Meng, Y.G.3
  • 36
    • 0032995027 scopus 로고    scopus 로고
    • Hepatic thrombopoietin mRNA levels in acute and chronic liver failure of childhood
    • Wolber EM, Ganschow R, Burdelski M, Jelkmann W. Hepatic thrombopoietin mRNA levels in acute and chronic liver failure of childhood. Hepatology 1999;29:1739-42.
    • (1999) Hepatology , vol.29 , pp. 1739-1742
    • Wolber, E.M.1    Ganschow, R.2    Burdelski, M.3    Jelkmann, W.4
  • 37
    • 0029046966 scopus 로고
    • Megakaryocyte growth and development factor. Analyses of in vitro effects on human megakaryopoiesis and endogenous serum levels during chemotherapy-induced thrombocytopenia
    • Nichol JL, Hokom MM, Hornkohl A, et al. Megakaryocyte growth and development factor. Analyses of in vitro effects on human megakaryopoiesis and endogenous serum levels during chemotherapy-induced thrombocytopenia. J Clin Invest 1995;95:2973-8.
    • (1995) J. Clin. Invest , vol.95 , pp. 2973-2978
    • Nichol, J.L.1    Hokom, M.M.2    Hornkohl, A.3
  • 38
    • 0034001439 scopus 로고    scopus 로고
    • Strong inverse correlation between serum TPO level and platelet count in essential thrombocythemia
    • Tomita N, Motomura S, Sakai R, et al. Strong inverse correlation between serum TPO level and platelet count in essential thrombocythemia. Am J Hematol 2000;63:131-5.
    • (2000) Am. J. Hematol , vol.63 , pp. 131-135
    • Tomita, N.1    Motomura, S.2    Sakai, R.3
  • 39
    • 0034050651 scopus 로고    scopus 로고
    • Recombinant human thrombopoietin attenuates carboplatin-induced severe thrombocytopenia and the need for platelet transfusions in patients with gynecologic cancer
    • Vadhan-Raj S, Verschraegen CF, Bueso-Ramos C, et al. Recombinant human thrombopoietin attenuates carboplatin-induced severe thrombocytopenia and the need for platelet transfusions in patients with gynecologic cancer. Ann Intern Med 2000;132:364-8.
    • (2000) Ann. Intern. Med , vol.132 , pp. 364-368
    • Vadhan-Raj, S.1    Verschraegen, C.F.2    Bueso-Ramos, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.