Serial positron emission tomographic findings in an atypical presentation of fatal familial insomnia

Archives of Neurology

Volumn 59, Issue 11, 2002, Pages 1815-1818

  Bär, Karl Jürgen ^a,b,c,d   Häger, Frank ^a,b,c,d   Nenadic, Igor ^a,b,c,d   Opfermann, T ^a,b,c,d   Brodhun, Michael ^a,b,c,d   Tauber, Ralf F ^a,b,c,d   Patt, Stephan ^a,b,c,d   Schulz Schaeffer, Walter ^a,b,c,d   Gottschild, Dietmar ^a,b,c,d   Sauer, Heinrich ^a,b,c,d  

^a Departments of Psychiatry   (Germany)

^b Department of Nuclear Medicine ^*  (Germany)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^d UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORODEOXYGLUCOSE;

ADULT; ARTICLE; ATAXIA; BRAIN METABOLISM; CASE REPORT; CLINICAL FEATURE; DEMENTIA; DYSAUTONOMIA; ELECTROENCEPHALOGRAPHY; FATAL FAMILIAL INSOMNIA; GENETIC ANALYSIS; HUMAN; MALE; POSITRON EMISSION TOMOGRAPHY; PRION DISEASE; PRIORITY JOURNAL;

HUMANS; INSOMNIA, FATAL FAMILIAL; MALE; MIDDLE AGED; THALAMUS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0036846682     PISSN: 00039942     EISSN: None     Source Type: Journal    
DOI: 10.1001/archneur.59.11.1815     Document Type: Article

References (10)

1. Lugaresi E, Medori R, Montagna P, et al. Fatal familial insomnia and dysautonomia with selective degeneration of thalamic nuclei. N Engl J Med. 1986;315:997-1003.
2. Lugaresi E, Tobler I, Gambetti P, Montagna P. The pathophysiology of fatal familial insomnia. Brain PathoL 1998;8:521-526.
3. Montagna P, Cortelli P, Avoni P, et al. Clinical features of fatal familial insomnia: Phenotypic variability in relation to a polymorphism at codon 129 of the prion protein gene. Brain PathoL 1998;8:515-520.
4. Zerr I, Giese A, Windl O, et al. Phenotypic variability in fatal familial insomnia (D178N-129M) 129" genotype. Neurology. 1998;51:1398-1405.
5. Tabernero C, Polo JM, Sevillano MD, et al. Fatal familial insomnia: Clinical, neuropathological, and genetic description of a Spanish family. J Neurol Neurosurg Psychiatry. 2000;68:774-777.
6. 18F]FDG-PET in fatal familial insomnia: The functional effects of thalamic lesions. Neurology. 1993;43:2565-2569.
7. Cortelli P, Perani D, Parchi P, et al. Cerebral metabolism in fatal familial insomnia: Relation to duration, neuropathology, and distribution of protease-resistant prion protein. Neurology. 1997;49:126-133.
8. Schulz-Schaeffer WJ, Tschoke S, Kranefuss N, et al. The paraffin-embedded tissue blot detects PrP(Sc) early in the incubation time in prion diseases. Am J Pathol. 2000;156:51-56.
9. Esteban JC, Atares B, Zarranz JJ, Velasco F, Lambarri I. Dementia, amyotrophy, and periodic complexes on the electroencephalogram: A diagnostic challenge. Arch Neurol. 2001;58:1669-1672.
10. Benarroch EE, Stotz-Potter EH. Dysautonomia in fatal familial insomnia as an indicator of the potential role of the thalamus in autonomic control. Brain Pathol. 1998;8:527-530.