Structured triglycerides containing medium-chain fatty acids and linoleic acid differently influence clearance rate in serum of triglycerides in rats

Nutrition Research

Volumn 22, Issue 11, 2002, Pages 1343-1351

  Kishi, Taiji ^a   Carvajal, Octavio ^a   Tomoyori, Hiroko ^a   Ikeda, Ikuo ^a   Sugano, Michihiro ^b   Imaizumi, Katsumi ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b PREFECTURAL UNIVERSITY OF KUMAMOTO   (Japan)

Author keywords

Chylomicrons; Linoleic acid; Lymph; Medium chain fatty acids; Retinyl palmitate; Structured triglycerides

Indexed keywords

CHYLOMICRON; LINOLEIC ACID; MEDIUM CHAIN FATTY ACID; RETINOL PALMITATE; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANNULATION; CLEARANCE; FOOD COMPOSITION; HALF LIFE TIME; INTERESTERIFICATION; LIPID METABOLISM; LYMPH LEVEL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SUPERIOR CAVA VEIN; THORACIC DUCT;

EID: 0036846415     PISSN: 02715317     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0271-5317(02)00441-4     Document Type: Article

References (22)

1. Greenberger NJ, Skillman TG. Medium-chain triglycerides. Physiologic considerations and clinical implications. New Eng J Med 1969;280:1045-58.
2. Bach AC, Babayan VK. Medium-chain triglycerides: An update. Amer J Clin Nutr 1982;36:950-62.
3. Anonymous. Rapid hydrolysis and absorption of structured medium-chain triglycerides. Nutr Rev 1988;46:228-30.
4. Jandacek RJ, Whiteside JA, Holcombe BN, Volpehnhein RA, Taulbee JD. The rapid hydrolysis and efficient absorption of triglycerides with octanoic acid in the 1 and 3 positions and long-chain fatty acid in the 2 position. Amer J Clin Nutr 1987;45:940-5.
5. Ikeda I, Tomari Y, Sugano M, Watanabe S, Nagata J. Lymphatic absorption of structured glycerolipids containing medium-chain fatty acids and linoleic acid, and their effect on cholesterol absorption in rats. Lipids 1991;26:369-73.
6. Carvajal O, Nakayama M, Kishi T, Sato M, Ikeda I, Sugano M, Imaizumi K. Effect of medium-chain fatty acid positional distribution in dietary triacylglycerol on lymphatic lipid transport and chylomicron composition in rats. Lipids 2000;35:1345-51.
7. Jensen MM, Christensen M S, Høy C-E. Intestinal absorption of octanoic, decanoic, and linoleic acids: Effect of triglyceride structure. Ann Rev Nutr 1994;11:104-16.
8. Christensen MS, Høy C-E, Becker CC, Redgrave TG. Intestinal absorption and lymphatic transport of eicosapentaenoic (EPA), docosahexaenoic (DHA), and decanoic acids: Dependence on intramolecular triacylglycerol structure. Amer J Clin Nutr 1995;61:56-61.
9. Mu H, Høy C-E. Effects of different medium-chain fatty acids on intestinal absorption of structured triacylglycerols. Lipids 2000;35:83-9.
10. Reeves PG, Nielsen FH, Fahey GC Jr. AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad hoc Writing Committee on the reformulation of the AIN-76A rodent diet. J Nutr 1993;123:1939-51.
11. Reime R, van Dongen JJ, Rensema JW. Permanent cannulation of the thoracic duct. In: van Dongen JJ, Temie R, Rensema JW, van Wunnik GHJ, editors. Manual of Microsurgery on the Laboratory Rat, Part I. Amsterdam: Elsevier, 1990. p. 243-54.
12. Copper AD. Hepatic uptake of chylomicron remnants. J Lipid Res 1997;38:2173-92.
13. van Bennekum AM, Kako Y, Weinstock PH, Harrison EH, Deckelbaum RJ, Goldberg IJ, Blaner WS. Lipoprotein lipase expression level influences tissue clearance of chylomicron retinyl ester. J Lipid Res 1999;40:565-74.
14. Folch J, Lees M, Sloane Stanley GH. A simple method for the isolation, and purification of total lipids from animal tissue. J Biol Chem 1957;226:497-509.
15. Ikeda I, Yoshida H, Tomooka M, Yosef A, Imaizumi K, Tsuji H, Seto A. Effects of long-term feeding of marine oils with different positional distribution of eicosapentaenoic and docosahexaenoic acids on lipid metabolism, eicosanoid production, and platelet aggregation in hypercholesterolemic rats. Lipids 1998;33:897-904.
16. Duncan DB. Multiple range and multiple F tests. Biometrics 1955;11:1-42.
17. Mu H, Høy C-E. Intestinal absorption of specific structured triacylglycerols. J Lipid Res 2001;42:792-798.
18. Redgrave TG, Kodali DR, Small DM. The effect of triacyl-sn-glycerol structure on the metabolism of chylomicrons and triacylglycerol-rich emulsions in the rat. J Biol Chem 1988;263:5118-23.
19. Mortimer B-C, Simmonds WJ, Cockman SJ, Stick RV, Redgrave TG. The effect of monostearoylglycerol on the metabolism of chylomicron-like lipid emulsions injected intravenously in rats. Biochim Biophys Acta 1990;1046:46-56.
20. Mortimer B-C, Simmonds WJ, Joll CA, Stick RV, Redgrave TG. Regulation of the metabolism of lipid emulsion model lipoproteins by a saturated acyl chain at the 2-position of triacylglycerol. J Lipid Res 1988;29:713-20.
21. Martins IJ, Mortimer B-C, Miller J, Redgrave TG. Effects of particle size and number on the plasma clearance of chylomicrons and remnants. J Lipid Res 1996;37:2696-705.
22. Karpe F, Hamsten A. Postprandial lipoprotein metabolism and atherosclerosis. Curr Opin Lipidol 1995;6:123-29.