Mechanism of the reduced elimination clearance of benzylpenicillin from cerebrospinal fluid in rats with intracisternal administration of lipopolysaccharide

Drug Metabolism and Disposition

Volumn 30, Issue 11, 2002, Pages 1214-1220

  Han, Hee ^a   Kim, Sang Geon ^a   Lee, Myung Gull ^a   Shim, Chang Koo ^a   Chung, Suk Jae ^a  

^a Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOPOLYSACCHARIDE; N(G) NITROARGININE; NITROPRUSSIDE SODIUM; PENICILLIN G; TAURINE; FORMYCIN B; FORMYCIN DERIVATIVE; NITRIC OXIDE; NITROGEN OXIDE; PENICILLIN DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; CEREBROSPINAL FLUID; CHOROID PLEXUS; CISTERNA MAGNA; CONTROLLED STUDY; DISTRIBUTION VOLUME; DRUG BRAIN LEVEL; DRUG CLEARANCE; DRUG ELIMINATION; DRUG TRANSPORT; INFLAMMATION; MALE; MENINGITIS; NONHUMAN; PRIORITY JOURNAL; RAT; ALGORITHM; ANIMAL; BRAIN; CYTOLOGY; LEUKOCYTE COUNT; METABOLISM; MICROINJECTION; SPRAGUE DAWLEY RAT;

ANIMALIA;

ALGORITHMS; ANIMALS; BRAIN; CEREBROSPINAL FLUID; CHOROID PLEXUS; CISTERNA MAGNA; FORMYCINS; LEUKOCYTE COUNT; LIPOPOLYSACCHARIDES; MALE; MICROINJECTIONS; NITRIC OXIDE; NITROGEN OXIDES; PENICILLIN G; PENICILLINS; RATS; RATS, SPRAGUE-DAWLEY; TAURINE;

EID: 0036842969     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.30.11.1214     Document Type: Article

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