Hyperosmotically induced volume change and calcium signaling in intervertebral disk cells: The role of the actin cytoskeleton

Biophysical Journal

Volumn 83, Issue 5, 2002, Pages 2502-2510

  Pritchard, Scott ^a   Erickson, Geoffrey R ^a   Guilak, Farshid ^a,b  

^a DUKE UNIVERSITY   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CYTOCHALASIN D; F ACTIN; PHALLOIDIN; ACTIN; CALCIUM; FLUORESCENT DYE;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL VOLUME; CONTROLLED STUDY; CYTOSKELETON; INTERVERTEBRAL DISK; LASER MICROSCOPY; NONHUMAN; NUCLEUS PULPOSUS; OSMOTIC STRESS; SECOND MESSENGER; SIGNAL TRANSDUCTION; SWINE; VISCOSITY; YOUNG MODULUS; ANIMAL; CONFOCAL MICROSCOPY; LUMBAR VERTEBRA; METABOLISM; OSMOSIS; OSMOTIC PRESSURE; PHYSIOLOGY; TIME;

ANIMALIA; SUS SCROFA;

ACTINS; ANIMALS; CALCIUM; CYTOSKELETON; FLUORESCENT DYES; INTERVERTEBRAL DISK; LUMBAR VERTEBRAE; MICROSCOPY, CONFOCAL; OSMOSIS; OSMOTIC PRESSURE; SIGNAL TRANSDUCTION; SWINE; TIME FACTORS;

EID: 0036841306     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(02)75261-2     Document Type: Article

References (72)

1. Alexopoulos, L., G. Erickson, and F. Guilak. 2002. A method for quantifying cell size from differential interference contract (DIC) images: Validation and application to osmotically stressed chondrocytes. J. Microsc. 205:125-135.
2. 2+ stores by cytochalasins. Exp. Cell Res. 234:379-387.
3. Antoniou, J., T. Steffen, F. Nelson, N. Winterbottom, A. P. Hollander, R. A. Poole, M. Aebi, and M. Alini. 1996. The human lumbar intervertebral disk: Evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, aging, and degeneration. J. Clin. Invest. 98:996-1003.
4. Asada, S., K. Fukuda, F. Nishisaka, M. Matsukawa, and C. Hamanisi. 2001. Hydrogen peroxide induces apoptosis of chondrocytes; involvement of calcium ion and extracellular signal-regulated protein kinase. Inflamm. Res. 50:19-23.
5. Baer, A. E., J. Y. Wang, V. B. Kraus, and L. A. Setton. 2001. Collagen gene expression and mechanical properties of intervertebral disk cell-alginate cultures. J. Orthop. Res. 19:2-10.
6. Banuett, F. 1998. Signaling in the yeasts: An informational cascade with links to the filamentous fungi. Microbiol. Mol. Biol. Rev. 62:249-274.
7. i in attached human fibroblasts responding to anisosmotic buffers. Am. J. Physiol. Cell Physiol. 266:C1639-C1649.
8. Buckwalter, J. A. 1995. Aging and degeneration of the human intervertebral disk. Spine. 20:1307-1314.
9. Bush, P. G., and A. C. Hall 2001. The osmotic sensitivity of isolated and in situ bovine articular chondrocytes. J. Orthop. Res. 19:768-778.
10. Cantiello, H. F. 1997. Role of actin filament organization in cell volume and ion channel regulation. J. Exp. Zool. 279:425-435.
11. Colliou, O. K., J. R. Chin, E. C. Liebenberg, and J. C. Lotz. 1998. Matrix disorganization, apoptosis and gene expression in the intervertebral disk are modulated by compressive loading: A mouse model for disk degeneration. Trans. Orthop. Res. Soc. 23:189.
12. Dascalu, A., R. Korenstein, Y. Oron, and Z. Nevo. 1996. A hyperosmotic stimulus regulates intracellular pH, calcium, and S-100 protein levels in avian chondrocytes. Biochem. Biophys. Res. Commun. 227:368-373.
13. Dascalu, A., A. Matithyou, Y. Oron, and R. Korenstein. 2000. A hyperosmotic stimulus elevates intracellular calcium and inhibits proliferation of a human keratinocyte cell line. J. Invest. Dermatol. 115:714-718.
14. Engstrom, K. G., B. Moller, and H. J. Meiselman. 1992. Optical evaluation of red blood cell geometry using micropipette aspiration. Blood Cells. 18:241-257.
15. Erickson, G. R., L. G. Alexopoulos, and F. Guilak. 2001. Hyperosmotic stress induces volume change and calcium transients in chondrocytes by transmembrane, phospholipid, and G-protein pathways. J. Biomech. 34:1527-1535.
16. Errington, R. J., K. Puustjarvi, I. R. F. White, S. Roberts, and J. P. G. Urban. 1998. Characterization of cytoplasm-filled processes in cells of the intervertebral disk. J. Anat. 192:369-378.
17. Guilak, F., G. R. Erickson, and H. P. Ting-Beall. 2002. The effects of osmotic stress on the viscoelastic and physical properties of articular chondrocytes. Biophys. J. 82:720-727.
18. Guilak, F., H. P. Ting-Beall, A. E. Baer, W. R. Trickey, G. R. Erickson, and L. A. Setton. 1999. Viscoelastic properties of intervertebral disk cells. Identification of two biomechanically distinct cell populations. Spine. 24:2475-2483.
19. Guizouarn, H., R. Motais, F. Garcia Romeu, and F. Borgese. 2000. Cell volume regulation: The role of taurine loss in maintaining membrane potential and cell pH. J. Physiol. 523(Pt 1):147-154.
20. + transport across the bovine articular chondrocyte membrane and their sensitivity to cell volume. Am. J. Physiol. Cell Physiol. 270:C1300-C1310.
21. Hallows, K. R., F. Y. Law, C. H. Packman, and P. A. Knauf. 1996. Changes in cytoskeletal actin content, F-actin distribution, and surface morphology during HL-60 cell volume regulation. J. Cell Physiol. 167:60-71.
22. Hamilton, M. T., D. S. Ward, and P. D. Watson. 1993. Effect of plasma osmolality on steady-state fluid shifts in perfused cat skeletal muscle. Am J. Physiol. Regulatory Integrative Comp. Physiol. 265:R1318-R1323.
23. Hardingham, G. E., and H. Bading. 1999. Calcium as a versatile second messenger in the control of gene expression. Microsc. Res. Tech. 46:348-355.
24. Henson, J. H. 1999. Relationships between the actin cytoskeleton and cell volume regulation. Microsc. Res. Tech. 47:155-162.
25. Hildebrandt, J. P., and A. Prowald. 2000. Ca(2+) and p38 MAP kinase regulate mAChR-mediated c-Fos expression in avian exocrine cells. Am J. Physiol. Cell Physiol. 278:C879-C884.
26. Hoffmann, E. K., and P. B. Dunham. 1995. Membrane mechanisms and intracellular signaling in cell volume regulation. Int. Rev. Cytol. 161:173-262.
27. Ingber, D. E., L. Dike, L. Hansen, S. Karp, H. Liley, A. Maniotis, H. McNamee, D. Mooney, G. Plopper, and J. Sims. 1994. Cellular tensegrity: Exploring how mechanical changes in the cytoskeleton regulate cell growth, migration, and tissue pattern during morphogenesis. Int. Rev. Cytol. 150:173-224.
28. Ishihara, H., H. Tsuji, N. Hirano, H. Ohshima, and N. Terahata. 1992. Effects of continuous quantitative vibration on rheologic and biological behaviors of the IVD. Spine. 17(Suppl):S7-S12.
29. Ishihara, H., K. Warensjo, S. Roberts, and J. P. Urban. 1997. Proteoglycan synthesis in the intervertebral disk nucleus: The role of extracellular osmolality. Am J. Physiol. Cell Physiol. 272:C1499-C1506.
30. Jones, W. R., G. M. Lee, S. S. Kelley, and F. Guilak. 1999. Viscoelastic properties of chondrocytes from normal and osteoarthritic human cartilage. Trans. Orthop. Res. Soc. 24:157.
31. Kajstura, J., and K. Reiss. 1989. F-actin organization influences the osmotic reactions of animal cells. Folia Histochem. Cytobiol. 27:201-208.
32. Kinosian, H. J., L. A. Selden, J. E. Estes, and L. C. Gershman. 1993. Actin filament annealing in the presence of ATP and phalloidin. Biochemistry. 32:12353-12357.
33. Lang, F., G. L. Busch, and H. Volkl. 1998. The diversity of volume regulatory mechanisms. Cell Physiol. Biochem. 8:1-45.
34. ++ signaling: A new view of an old problem. J. Cell Physiol. 180:19-34.
35. Lange, K. 2000. Regulation of cell volume via microvillar ion channels. J. Cell Physiol. 185:21-35.
36. Lange, K., and U. Brandt. 1996. Calcium storage and release properties of F-actin: Evidence for the involvement of F-actin in cellular calcium signaling. FEBS Lett. 395:137-142.
37. Le Bihan, T., and C. Gicquaud. 1991. Stabilization of actin by phalloidin: A differential scanning calorimetric study. Biochem. Biophys. Res. Commun. 181:542-547.
38. Lipp, P., and E. Niggli. 1993. Ratiometric confocal Ca(2+)-measurements with visible wavelength indicators in isolated cardiac myocytes. Cell Calcium. 14:359-372.
39. Maldonado, B. A., and T. R. Oegema. 1992. Initial characterization of the metabolism of intervertebral disk cells encapsulated in microspheres. J. Orthop. Res. 10:677-690.
40. Malko, J. A., W. C. Hutton, and W. A. Fajman. 1999. An in vivo magnetic resonance imaging study of changes in the volume (and fluid content) of the lumbar intervertebral disks during a simulated diurnal load cycle. Spine. 24:1015-1022.
41. Maximov, A. V., E. A. Vedernikova, H. Hinssen, S. Y. Khaitlina, and Y. A. Negulyaev. 1997. Ca-dependent regulation of Na+-selective channels via actin cytoskeleton modification in leukemia cells. FEBS Lett. 412:94-96.
42. McCarty, N. A., and R. G. O'Neil. 1992. Calcium signaling in cell volume regulation. Physiol. Rev. 72:1037-1061.
43. McMillan, D. W., G. Garbutt, and M. A. Adams. 1996. Effect of sustained loading on the water content of intervertebral disks: Implications for disk metabolism. Ann. Rheum. Dis. 55:880-887.
44. Moustakas, A., P. A. Theodoropoulos, A. Gravanis, D. Haussinger, and C. Stournaras. 1998. The cytoskeleton in cell volume regulation. Contrib. Nephrol. 123:121-134.
45. Oegema, T. R. 1993. Biochemistry of the intervertebral disk. Clin. Sports Med. 12:419-439.
46. Ohshima, H., H. Tsuji, N. Hirano, H. Ishihara, Y. Katoh, and H. Yamada. 1989. Water diffusion pathway, swelling pressure, and biomechanical properties of the intervertebral disk during compression load. Spine. 14:1234-1244.
47. Ohshima, H., J. P. Urban, and D. H. Bergel. 1995. Effect of static load on matrix synthesis rates in the intervertebral disk measured in vitro by a new perfusion technique. J. Orthop. Res. 13:22-29.
48. O'Neill, W. C. 1999. Physiological significance of volume-regulatory transporters. Am. J. Physiol. Cell Physiol. 276:C995-C1011.
49. Paajanen, H., I. Lehto, A. Alanen, M. Erkintalo, and M. Komu. 1994. Diurnal fluid changes of lumbar disks measured indirectly by magnetic resonance imaging. J. Orthop. Res. 12:509-514.
50. Perlman, D. F., and L. Goldstein. 1999. Organic osmolyte channels in cell volume regulation in vertebrates. J. Exp. Zool. 283:725-733.
51. Ragette, R., C. Fu, and J. Bhattacharya. 1997. Barrier effects of hyperosmolar signaling in microvascular endothelium of rat lung. J. Clin. Invest. 100:685-692.
52. Rivero, F., B. Koppel, B. Peracino, S. Bozzaro, F. Siegert, C. J. Weijer, M. Schleicher, R. Albrecht, and A. A. Noegel. 1996. The role of the cortical cytoskeleton: F-actin crosslinking proteins protect against osmotic stress, ensure cell size, cell shape and motility, and contribute to phagocytosis and development. J. Cell Sci. 109(Pt. 11):2679-2691.
53. Rosado, J. A., and S. O. Sage. 2000. The actin cytoskeleton in store-mediated calcium entry. J. Physiol. 526(Pt 2):221-229.
54. Sato, M., D. P. Theret, L. T. Wheeler, N. Ohshima, and R. M. Nerem. 1990. Application of the micropipette technique to the measurement of cultured porcine aortic endothelial cell viscoelastic properties. J. Biomech. Eng. 112:263-268.
55. Schliess, F., R. Sinning, R. Fischer, C. Schmalenbach, and D. Haussinger. 1996. Calcium-dependent activation of Erk-1 and Erk-2 after hypoosmotic astrocyte swelling. Biochem. J. 320(Pt. 1):167-171.
56. Schliwa, M. 1982. Action of cytochalasin D on cytoskeletal networks. J. Cell Biol. 92:79-91.
57. Sheikh, S., W. B. Gratzer, J. C. Pinder, and G. B. Nash. 1997. Actin polymerization regulates integrin -mediated adhesion as well as rigidity of neutrophils. Biochem. Biophys. Res. Commun. 238:910-915.
58. Small, J. V., and M. Gimona. 1998. The cytoskeleton of the vertebrate smooth muscle cell. Acta Physiol. Scand. 164:341-348.
59. Ting-Beall, H. P., A. S. Lee, and R. M. Hochmuth. 1995. Effect of cytochalasin D on the mechanical properties and morphology of passive human neutrophils. Ann. Biomed. Eng. 23:666-671.
60. Toribatake, Y., W. C. Hutton, W. A. Elmer, T. E. Whitesides, and K. Tomita. 1997. An in vivo study of the effect of applied compressive force on intervertebral disk metabolism. Trans. Orthop. Res. Soc. 22:145.
61. Trickey, W., T. Vail, T. Wright, and F. Guilak. 2000. The role of the cytoskeleton in the viscoelastic properties of osteoarthritic human chondrocytes. Trans. Orthop. Res. Soc. 25:930.
62. Trout, J. J., J. A. Buckwalter, K. C. Moore, and S. K. Landas. 1982. Ultrastructure of the human intervertebral disk. I. Changes in notochordal cells with age. Tissue Cell. 14:359-369.
63. Tsai, M. A., R. S. Frank, and R. E. Waugh. 1994. Passive mechanical behavior of human neutrophils: Effect of cytochalasin B. Biophys. J. 66:2166-2172.
64. Tseng, Y., E. Fedorov, J. M. McCaffery, S. C. Almo, and D. Wirtz. 2001. Micromechanics and ultrastructure of actin filament networks crosslinked by human fascin: A comparison with alpha-actinin. J. Mol. Biol. 310:351-366.
65. Urban, J. P., H. Ishihara, and M. J. Mouat. 1994. Differential metabolic responses of the nucleus and outer annulus to changes in extracellular physical factors. Trans. Orthop. Res. Soc. 19:134.
66. Verkman, A. S., A. N. van Hoek, T. Ma, A. Frigeri, W. R. Skach, A. Mitra, B. K. Tamarappoo, and J. Farinas. 1996. Water transport across mammalian cell membranes. Am J. Physiol. Cell Physiol. 270:C12-C30.
67. Waldegger, S., S. Steuer, T. Risler, A. Heidland, G. Capasso, S. Massry, and F. Lang. 1998. Mechanisms and clinical significance of cell volume regulation. Nephrol. Dial. Transplant. 13:867-874.
68. Wang, N. 1998. Mechanical interactions among cytoskeletal filaments. Hypertension. 32:162-165.
69. Wang, J. Y., A. E. Baer, V. B. Kraus, and L. A. Setton. 2001. Intervertebral disk cells exhibit differences in gene expression in alginate and monolayer culture. Spine. 26:1747-1752.
70. Warskulat, U., F. Schliess, and D. Haussinger. 1998. Compatible organic osmolytes and osmotic modulation of inducible nitric oxide synthetase in RAW 264.7 mouse macrophages. Biol. Chem. 379:867-874.
71. Wendel, H., and P. Dancker. 1987. Influence of phalloidin on both the nucleation and the elongation phase of actin polymerization. Biochim. Biophys. Acta. 915:199-204.
72. Wu, Z. Z., G. Zhang, M. Long, H. B. Wang, G. B. Song, and S. X. Cai. 2000. Comparison of the viscoelastic properties of normal hepatocytes and hepatocellular carcinoma cells under cytoskeletal perturbation. Biorheology. 37:279-290.