Hyper-osmotic stress induces volume change and calcium transients in chondrocytes by transmembrane, phospholipid, and G-protein pathways

Journal of Biomechanics

Volumn 34, Issue 12, 2001, Pages 1527-1535

  Erickson, Geoffrey R ^a   Alexopoulos, Leonidas G ^a   Guilak, Farshid ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Articular cartilage; Ca2+; Cell volume; IP3; Osteoarthritis

Indexed keywords

BIOLOGICAL MEMBRANES; CALCIUM; CARTILAGE; MICROSCOPIC EXAMINATION; PHOSPHOLIPIDS; PROTEINS;

OSMOTIC STRESSES;

BIOMECHANICS;

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; CALCIUM ION; GADOLINIUM; GUANINE NUCLEOTIDE BINDING PROTEIN; THAPSIGARGIN;

ANIMAL CELL; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CELL VOLUME; CONTROLLED STUDY; EXTRACELLULAR MATRIX; NONHUMAN; OSCILLATION; OSMOLALITY; OSMOTIC STRESS; OSTEOARTHRITIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; CALCIUM; CALCIUM SIGNALING; CELLS, CULTURED; CHONDROCYTES; CULTURE MEDIA; GTP-BINDING PROTEINS; INTRACELLULAR MEMBRANES; OSMOLAR CONCENTRATION; OSMOTIC PRESSURE; PHOSPHOLIPIDS; SWINE; TIME FACTORS;

EID: 0034753575     PISSN: 00219290     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9290(01)00156-7     Document Type: Article

References (62)

1. Slow oscillations of free intracellular calcium ion concentration in human fibroblasts responding to mechanical stretch
2. Calcium oscillations
3. 2+ inflow in hepatocytes
4. Intercellular propagation of calcium waves mediated by inositol trisphosphate
5. Membrane potential changes associated with calcium signals in human lymphocytes and rat mast cells
6. Plasmalogen-derived lysolipid induces a depolarizing cation current in rabbit ventricular myocytes
7. Intracellular calcium homeostasis
8. Inositol trisphosphate may be a second messenger in regulatory volume decrease in Ehrlich mouse ascite tumor cells (Abstract)
9. Effects of thapsigargin, an intracellular calcium-mobilizing agent, on synthesis and secretion of cartilage collagen and proteoglycan
10. 3+-sensitive cation current and cell volume regulation in rabbit ventricular myocytes
11. 2+ waves in mechanically stimulated articular chondrocytes
12. A hyperosmotic stimulus regulates intracellular pH, calcium, and S-100 protein levels in avian chondrocytes
13. Hyperosmotic modulation of the cytosolic calcium concentration in a rat osteoblast-like cell line
14. Chronic, intermittent loading alters mechanosensitive channel characteristics in osteoblast-like cells
15. Calcium induced release of calcium from the sarcoplasmic reticulum of skinned skeletal muscle fibres
16. Four-dimensional imaging of living chondrocytes in cartilage using confocal microscopy; a pragmatic approach
17. Involvement of calcium and cytoskeleton in gallbladder epithelial cell volume regulation
18. Zonal differences in nitric oxide synthesis by bovine chondrocytes exposed to interleukin-1
19. Compression-induced changes in the shape and volume of the chondrocyte nucleus
20. Chondrocyte deformation and local tissue strain in articular cartilage; a confocal microscopy study
21. Physical regulation of cartilage metabolism
22. Mechanically induced calcium waves in articular chondrocytes are inhibited by gadolinium and amiloride
23. Gadolinium inhibits mechanoelectrical transduction in rabbit carotid baroreceptors. Implication of stretch-activated channels
24. Volume-sensitive taurine transport in bovine articular chondrocytes
25. The cellular physiology of articular cartilage
26. The pharmacology of mechanogated membrane ion channels
27. Calcium as a versatile second messenger in the control of gene expression [Review]
28. The structure, function and turnover of aggrecan, the large aggregating proteoglycan from cartilage
29. 2+ response of bone cells experiencing fluid flow
30. Growth plate matrix vesicle biogenesis. The role of intracellular calcium
31. 2+/calmodulin and protein kinase C dependent pathways
32. Synthesis of cartilage matrix by mammalian chondrocytes in vitro. I. Isolation, culture characteristics, and morphology
33. Conditional equivalence of chemical and mechanical loading on articular cartilage
34. The diversity of volume regulatory mechanisms
35. ++ signaling; a new view of an old problem
36. Ratiometric confocal Ca(2+)-measurements with visible wavelength indicators in isolated cardiac myocytes
37. Induction of nitric oxide synthase mRNA by shear stress requires intracellular calcium and G-protein signals and is modulated by PI 3 kinase
38. 2+ concentration in endothelium of intact rat aorta
39. Physicochemical properties of articular cartilage
40. Calcium signaling in cell volume regulation
41. Hyperosmotic stress induces rapid synthesis of phosphatidyl-D-inositol 3,5-bisphosphate in plant cells
42. Cartilage and diarthrodial joints as paradigms for hierarchical materials and structures
43. Modulation of mechanically induced calcium waves in hippocampal astroglial cells. Inhibitory effects of alpha 1-adrenergic stimulation
44. Slowing down aging of cultured embryonal chick chondrocytes by maintenance under lowered oxygen tension
45. Physiological significance of volume-regulatory transporters [Review]
46. CD44 expression is up-regulated in the deep zone of osteoarthritic cartilage from human femoral heads
47. Slow feedback inhibition of calcium release-activated calcium current by calcium entry
48. Store depletion and calcium influx
49. + exchanger in Ehrlich Ascites tumor cells-mechanisms involved in the activation and a role for the exchanger in cell volume regulation
50. Different mechanisms are involved in intracellular calcium increase by insulin-like growth factors 1 and 2 in articular chondrocytes; voltage-gated calcium channels, and/or phospholipase C coupled to a pertussis-sensitive G-protein
51. Mechanical transduction in biological systems
52. Effects of mechanical and osmotic pressure on the rate of glycosaminoglycan synthesis in the human adult femoral head cartilage; an in vitro study
53. Electroporation-induced formation of individual calcium entry sites in the cell body and processes of adherent cells
54. The chondrocyte; a cell under pressure
55. Regulation of matrix synthesis rates by the ionic and osmotic environment of articular chondrocytes
56. Chondrocyte biosynthesis correlates with local tissue strain in statically compressed adult articular cartilage
57. Effects of intermittent pressure-induced strain on the electrophysiology of cultured human chondrocytes; evidence for the presence of stretch-activated membrane ion channels
58. Block of stretch-activated ion channels in xenopus oocytes by gadolinium and calcium ions
59. Effects of fluid flow on intracellular calcium in bovine articular chondrocytes
60. 2+ mobilization in articular chondrocytes