Nosocomial infections caused by multidrug-resistant isolates of Pseudomonas putida producing VIM-1 metallo-β-lactamase

Journal of Clinical Microbiology

Volumn 40, Issue 11, 2002, Pages 4051-4055

  Lombardi, Gianluigi ^a   Luzzaro, Francesco ^a   Docquier, Jean Denis ^a   Riccio, Maria Letizia ^a   Perilli, Mariagrazia ^a   Colì, Alessandra ^a   Amicosante, Gianfranco ^a   Rossolini, Gian Maria ^a   Toniolo, Antonio ^a  

^a UNIVERSITY OF SIENA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; BETA LACTAMASE; CARBAPENEM; ENZYME; METALLO BETA LACTAMASE; PROTEIN VIM 1; UNCLASSIFIED DRUG;

ACHROMOBACTER; ADULT; AGED; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM CONJUGATION; BACTERIUM ISOLATE; CASE REPORT; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE CASSETTE; GENE STRUCTURE; GRAM NEGATIVE INFECTION; HOSPITAL INFECTION; HUMAN; INTEGRON; INTENSIVE CARE UNIT; ITALY; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR EVOLUTION; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS PUTIDA; PULSED FIELD GEL ELECTROPHORESIS; SEQUENCE ANALYSIS;

AGED; BETA-LACTAMASES; BETA-LACTAMS; CARBAPENEMS; CROSS INFECTION; DRUG RESISTANCE, MULTIPLE, BACTERIAL; HUMANS; INTEGRONS; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PSEUDOMONAS INFECTIONS; PSEUDOMONAS PUTIDA; URINARY TRACT INFECTIONS;

ACHROMOBACTER; ACHROMOBACTER XYLOSOXIDANS; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS PUTIDA;

EID: 0036840934     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.40.11.4051-4055.2002     Document Type: Article

References (33)

1. Ambler, R. P. 1980. The structure of beta-lactamases. Philos. Trans. R. Soc. Lond. B Biol. Sci. 289:321-331.
2. Anaissie, E., V. Fainstein, P. Miller, H. Kassamali, S. Pitlik, G. Bodey, and K. Rolston. 1987. Pseudomonas putida. Newly recognized pathogen in patients with cancer. Am. J. Med. 82:1191-1194.
3. Bush, K., G. A. Jacoby, and A. A. Medeiros. 1995. A functional classification scheme for β-lactamases and its correlation with molecular structure. Antimicrob. Agents Chemother. 39:1211-1233.
4. Bush, K. 2001. New β-lactamases in gram-negative bacteria: Diversity and impact on the selection of antimicrobial therapy. Clin. Infect. Dis. 32:1085-1089.
5. Cardoso, O., J. C. Sousa, R. Leitãao, and L. Peixe. 1999. Carbapenem hydrolysing β-lactamase from clinical isolates of Pseudomonas aeruginosa in Portugal. J. Antimicrob. Chemother. 44:135.
6. Cornaglia, G., M. L. Riccio, A. Mazzariol, L. Lauretti, R. Fontana, and G. M. Rossolini. 1999. Appearance of IMP-1 metallo-β-lactamase in Europe. Lancet 353:899-900.
7. Cornaglia, G., A. Mazzariol, L. Lauretti, G. M. Rossolini, and R. Fontana. 2000. Hospital outbreak of carbapenem-resistant Pseudomonas aeruginosa producing VIM-1, a novel transferable metallo-β-lactamase. Clin. Infect. Dis. 31:1119-1125.
8. Croize, J., D. Rouhan, and P. Le Noc. 1987. Identification des bacilles à Gram négatif aérobies et aéro-anaérobies non exigeants par le Système ATB 32 GN. Ann. Biol. Clin. 45:74-77.
9. Docquier, J.-D., F. Luzzaro, G. Amicosante, A. Tuniolo, and G. M. Rossolini. 2001. Multidrug-resistant Pseudomonas aeruginosa producing PER-1 extended-spectrum serine-β-lactamase and VIM-2 metallo-β-lactamase. Emerg. Infect. Dis. 7:910-911.
10. Franceschini, N., B. Caravelli, J.-D. Docquier, M. Galleni, J.-M. Frère, G. Amicosante, and G. M. Rossolini. 2000. Purification and biochemical characterization of the VIM-1 metallo-β-lactamase. Antimicrob. Agents Chemother. 44:3003-3007.
11. IMP. Antimicrob. Agents Chemother. 42:2006-2011.
12. Johnson, J. L. 1994. Similarity analysis of DNAs, p. 655-682. In P. Gerhardt, R. G. E. Murray, W. A. Wood, and N. R. Krieg (ed.), Methods for General and Molecular Bacteriology. American Society for Microbiology, Washington, D.C.
13. Ladhani, S., and Z. A. Bhutta. 1998. Neonatal Pseudomonas putida infection presenting as staphylococcal scalded skin syndrome. Eur. J. Clin. Microbiol. Infect. Dis. 17:642-644.
14. VIM-1, a new integron-borne metallo-β-lactamase gene from a Pseudomonas aeruginosa clinical isolate. Antimicrob. Agents Chemother. 43:1584-1590.
15. VIM-2 cassette-containing novel integrons in metallo-β-lactamase-producing Pseudomonas aeruginosa and Pseudomonas putida isolates disseminated in a Korean hospital. Antimicrob. Agents Chemother. 46:1053-1058.
16. Livermore, D. M., and N. Woodford. 2000. Carbapenemases: A problem in waiting? Curr. Opin. Microbiol. 3:489-495.
17. Luzzaro, F., E. Mantengoli, M. Perilli, G. Lombardi, V. Orlandi, A. Orsatti, G. Amicosante, G. M. Rossolini, and A. Toniolo. 2001. Dynamics of a nosocomial outbreak of multidrug-resistant Pseudomonas aeruginosa producing the PER-1 extended-spectrum β-lactamase. J. Clin. Microbiol. 39:1865- 1870.
18. Martino, R., C. Martinez, R. Pericas, R. Salazar, C. Sola, S. Brunet, A. Sureda, and A. Domingo-Albos. 1996. Bacteremia due to glucose non-fermenting gram-negative bacilli in patients with hematological neoplasias and solid tumors. Eur. J. Clin. Microbiol. Infect. Dis. 15:610-615.
19. National Committee for Clinical Laboratory Standards. 2000. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically, 5th Ed. Approved standard M7-A5. National Committee for Clinical Laboratory Standards, Wayne, Pa.
20. Poirel, L., T. Naas, D. Nicolas, L. Collet, S. Bellais, J.-D. Cavallo, and P. Nordmann. 2000. Characterization of VIM-2, a carbapenem-hydrolyzing metallo-β-lactamase and its plasmid- and integron-borne gene from a Pseudomonas aeruginosa clinical isolate in France. Antimicrob. Agents Chemother. 44:891-897.
21. Prats, G., E. Miro, B. Mirelis, L. Poirel, S. Bellais, and P. Nordmann. 2002. First isolation of a carbapenem-hydrolyzing β-lactamase in Pseudomonas aeruginosa in Spain. Antimicrob. Agents Chemother. 46:932-933.
22. Ramos-Diaz, M. A., and J. L. Ramos. 1998. Combined physical and genetic map of the Pseudomonas putida KT2440 chromosome. J. Bacteriol. 180:6352-6363.
23. IMP allelic variants carried by gene cassettes of different phylogeny. Antimicrob. Agents Chemother. 44:1229-1235.
24. VIM-1-containing integron carrying a new aminoglycoside phosphotransferase gene cassette. Antimicrob. Agents Chemother. 45:1249-1253.
25. VIM metallo-β-lactamase determinants, Italy. Emerg. Infect. Dis. 6:312-313.
26. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular Cloning: A Laboratory Manual, 2nd Ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
27. Sanford, J. P. 1995. Pseudomonas species (including melioidosis and glanders), p. 2003-2009. In G. L. Mandell, J. E. Bennett, and R. Dolin (ed.), Principles and Practice of Infectious Diseases, 4th Ed. Churchill Livingstone, New York, N.Y.
28. Senda, K., Y. Arakawa, K. Nakashima, H. Ito, S. Ichiyama, K. Shimokata, N. Kato, and M. Ohta. 1996. Multifocal outbreaks of metallo-β-lactamase-producing Pseudomonas aeruginosa resistant to broad-spectrum β-lactams, including carbapenems. Antimicrob. Agents Chemother. 40:349-353.
29. IMP) in gram-negative rods resistant to broad-spectrum β-lactams. J. Clin. Microbiol. 34:2909-2913.
30. Tenover, F. C., R. D. Arbeit, R. V. Goering, P. A. Mickelsen, B. E. Murray, D. H. Persing, and B. Swaminathan. 1995. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: Criteria for bacterial strain typing. J. Clin. Microbiol. 33:2233-2239.
31. Tsakris, A., S. Pournaras, N. Woodford, M.-F. I. Palepou, G. S. Babini, J. Douboyas, and D. M. Livermore. 2000. Outbreak of infections caused by Pseudomonas aeruginosa producing VIM-1 carbapenemase in Greece. J. Clin. Microbiol. 38:1290-1292.
32. Tsao, S. G., C. F. Brunk, and R. E. Pearlman. 1983. Hybridization of nucleic acids directly in agarose gels. Anal. Biochem. 131:365-372.
33. Yan, J.-J., P.-R. Hsueh, W.-C. Ko, K.-T. Luh, S.-H. Tsai, H.-M. Wu, and J.-J. Wu. 2001. Metallo-β-lactamases in clinical Pseudomonas isolates in Taiwan and identification of VIM-3, a novel variant of the VIM-2 enzyme. Antimicrob. Agents Chemother. 45:2224-2228.