Functional and molecular characterization of the shark renal Na-K-Cl cotransporter: Novel aspects

American Journal of Physiology - Renal Physiology

Volumn 283, Issue 5 52-5, 2002, Pages

  Gagnon, Édith ^a   Forbush, Biff ^b,c   Flemmer, Andreas W ^b   Giménez, Ignacio ^b   Caron, Luc ^a   Isenring, Paul ^a  

^a UNIVERSITÉ LAVAL   (Canada)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MOUNT DESERT ISLAND BIOLOGICAL LABORATORY   (United States)

Author keywords

Cation chloride cotransporter; Splice variant; Squalus acanthias; Thick ascending loop of Henle

Indexed keywords

ANTIPORTER; SODIUM POTASSIUM CHLORIDE COTRANSPORTER;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EXON; HUMAN; HUMAN CELL; JUXTAGLOMERULAR APPARATUS; KIDNEY; MACULA DENSA; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN ISOLATION; PROTEIN VARIANT; REGULATORY MECHANISM; SHARK; VERTEBRATE; XENOPUS LAEVIS;

EID: 0036839417     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00107.2002     Document Type: Article

References (53)

1. Beck PJ, Orlean P, Albright C, Robbins PW, Gething MJ, and Sambrook JF. The Saccharomyces cerevisiae DPM1 gene encoding dolichol-phosphate-mannose synthase is able to complement a glycosylation-defective mammalian cell line. Mol Cell Biol 10: 4612-4622, 1990.
2. Biemesderfer D, Payne JA, Lytle CY, and Forbush B. Immunocytochemical studies of the Na-K-Cl cotransporter of shark kidney. Am J Physiol Renal Fluid Electrolyte Physiol 270: F927-F936, 1996.
3. Canessa CM, Schild L, Buell G, Thorens B, Gautschi I, Horisberger JD, and Rossier BC. Amiloride-sensitive epithelial Na channel is made of three homologous subunits. Nature 367: 463-467, 1994.
4. Caron L, Rousseau F, Gagnon E, and Isenring P. Cloning and functional characterization of a cation-Cl cotransporter-interacting protein. J Biol Chem 275: 32027-32036, 2000.
5. Darman RB, Flemmer A, and Forbush B. Modulation of ion transport by direct targeting of protein phosphatase type 1 to the Na-K-Cl cotransporter. J Biol Chem 276: 34359-34362, 2001.
6. Gagnon E, Caron L, Forbush B, and Isenring P. Activation of NKCC2 splice variants expressed in Xenopus laevis oocytes (Abstract). J Am Soc Nephrol 10: 32A, 1999.
7. Gagnon E, Caron L, and Isenring P. Functional characterization of the kidney-specific Na-K-2Cl cotransporter from the shark Squalus acanthias (Abstract). J Am Soc Nephrol 11: 28A, 2000.
8. Gamba G, Miyanoshita A, Lombardi M, Lytton J, Lee WS, Hediger MA, and Hebert SC. Molecular cloning, primary structure, and characterization of two members of the mammalian electroneutral sodium-(potassium)-chloride cotransporter family expressed in kidney. J Biol Chem 269: 17713-17722, 1994.
9. Gamba G, Saltzberg SN, Lombardi M, Miyanoshita A, Lytton J, Hediger MA, Brenner BM, and Hebert SC. Primary structure and functional expression of a cDNA encoding the thiazide-sensitive, electroneutral sodium-chloride cotransporter. Proc Natl Acad Sci USA 90: 2749-2753, 1993.
10. Gillen CM, Brill S, Payne JA, and Forbush B. Molecular cloning and functional expression of the K-Cl cotransporter from rabbit, rat, and human. A new member of the cation-chloride cotransporter family. J Biol Chem 271: 16237-16244, 1996.
11. Giménez I, Isenring P, and Forbush B. Alternative splicing introduces differences in ion affinities between the cortical and the medullar isoforms of the renal Na-K-Cl cotransporter (Abstract). J Am Soc Nephrol 10: 32A, 1999.
12. Giménez I, Isenring P, and Forbush B. Spatially distributed alternative splice variants of the renal Na-K-Cl cotransporter exhibit dramatically different affinities for the transported ions. J Biol Chem 277: 8767-8770, 2002.
13. Greger R. Ion transport mechanisms in thick ascending limb of Henle's loop of mammalian nephron. Physiol Rev 65: 760-797, 1985.
14. Greger R, Heitzmann D, Hug MJ, Hoffmann EK, and Bleich M. The Na-2Cl-K cotransporter in the rectal gland of Squalus acanthias is activated by cell shrinkage. Pflügers Arch 438: 165-176, 1999.
15. Haas M and Forbush B. The Na-K-Cl cotransporters. J Bioenerg Biomembr 30: 161-172, 1998.
16. Haas M and Forbush B. The Na-K-Cl cotransporter of secretory epithelia. Annu Rev Physiol 62: 515-534, 2000.
17. Hebert SC and Gamba G. Molecular cloning and characterization of the renal diuretic-sensitive electroneutral sodium(potassium)-chloride cotransporters. Clin Invest 72: 692-694, 1994.
18. 1-Na,K-ATPase and Na, K,2Cl-cotransporter/D3mit3 loci interact to increase susceptibility to salt-sensitive hypertension in Dahl S (HSD) rats. Mol Med 7: 125-134, 2001.
19. Ichinose M, Hall AE, Cheng S, Xu JZ, and Hebert SC. Novel structure of the flounder thiazide-sensitive Na-Cl cotransporter (flTSC) in the flounder urinary bladder (Abstract). J Am Soc Nephrol 10: 34A, 1999.
20. Igarashi P, Vanden Heuvel GB, Payne JA, and Forbush B. Cloning, embryonic expression, and alternative splicing of a murine kidney-specific Na-K-Cl cotransporter. Am J Physiol Renal Fluid Electrolyte Physiol 269: F405-F418, 1995.
21. Isenring P and Forbush B. Ion and bumetanide binding by the Na-K-Cl cotransporter: Importance of transmembrane domain. J Biol Chem 272: 24556-24562, 1997.
22. Isenring P and Forbush B. Ion transport and ligand binding by the Na-K-Cl cotransporter, structure-function studies. Comp Biochem Physiol 130: 487-497, 2001.
23. Isenring P, Gagnon E, and Caron L. Cloning and functional characterization of a cation-Cl cotransporter-interacting protein (Abstract). J Am Soc Nephrol 11: 30A, 2000.
24. Isenring P, Jacoby SC, Chang J, and Forbush B. Mutagenic mapping of the Na-K-Cl cotransporter for domains involved in ion transport and bumetanide binding. J Gen Physiol 112: 549-558, 1998.
25. Isenring P, Jacoby SC, and Forbush B. Comparison of Na-K-Cl cotransporters: NKCC1, NKCC2, and the HEK cell Na-K-Cl cotransporter. J Biol Chem 273: 11295-11301, 1998.
26. Isenring P, Jacoby SC, and Forbush B. The role of transmembrane domain 2 in cation transport by the Na-K-Cl cotransporter. Proc Natl Acad Sci USA 95: 7179-7184, 1998.
27. Jacoby SC, Gagnon E, Caron L, Chang J, and Isenring P. Inhibition of Na-K-2Cl cotransport by mercury. Am J Physiol Cell Physiol 277: C684-C692, 1999.
28. Ji HL, Fuller CM, and Benos DJ. Osmotic pressure regulates αβγ-rENaC expressed in Xenopus oocytes. Am J Physiol Cell Physiol 275: C1182-C1190, 1998.
29. Kaplan MR, Plotkin MD, Lee WS, Xu ZC, Lytton J, and Hebert SC. Apical localization of the Na-K-Cl cotransporter, rBSC1, on rat thick ascending limbs. Kidney Int 49: 40-47, 1996.
30. Kreusch A, Pfaffinger PJ, Stevens CF, and Choe S. Crystal structure of the tetramerization domain of the Shaker potassium channel. Nature 392: 945-948, 1998.
31. Lacy ER and Reale E. The presence of a juxtaglomerular apparatus in elasmobranch fish. Anat Embryol (Berl) 182: 249-262, 1990.
32. Lapointe JY, Bell PD, and Cardinal J. Direct evidence for apical Na:2Cl:K cotransport in macula densa cells. Am J Physiol Renal Fluid Electrolyte Physiol 258: F1466-F1469, 1990.
33. Lytle C and Forbush B. Regulatory phosphorylation of the secretory Na-K-Cl cotransporter: Modulation by cytoplasmic Cl. Am J Physiol Cell Physiol 270: C437-C448, 1996.
34. Lytle CY, Xu JC, Biemesderfer D, and Forbush B. Distribution and diversity of Na-K-Cl cotransport proteins: A study with monoclonal antibodies. Am J Physiol Cell Physiol 269: C1496-C1505, 1995.
35. Moore-Hoon ML and Turner RJ. The structural unit of the secretory Na-K-2Cl cotransporter (NKCC1) is a homodimer. Biochemistry 39: 3718-3724, 2000.
36. Mount DB, Mercado A, Song L, Xu J, George AL, Delpire E, and Gamba G. Cloning and characterization of KCC3 and KCC4, new members of the cation-chloride cotransporter gene family. J Biol Chem 274: 16355-16362, 1999.
37. Neely JD, Christensen BM, Nielsen S, and Agre P. Heterotetrameric composition of aquaporin-4 water channels. Biochemistry 38: 11156-11163, 1999.
38. Nishimura H and Bailey JR. Intrarenal renin-angiotensin system in primitive vertebrates. Kidney Int 12: S185-S192, 1982.
39. Payne JA and Forbush B. Alternatively spliced isoforms of the putative renal Na-K-Cl cotransporter are differentially distributed within the rabbit kidney. Proc Natl Acad Sci USA 91: 4544-4548, 1994.
40. Payne JA, Stevenson TJ, and Donaldson LF. Molecular characterization of a putative K-Cl cotransporter in rat brain. A neuronal-specific isoform. J Biol Chem 271: 16245-16252, 1996.
41. Payne JA, Xu JC, Haas M, Lytle CY, Ward D, and Forbush B. Primary structure, functional expression, and chromosomal localization of the bumetanide-sensitive Na-K-Cl cotransporter in human colon. J Biol Chem 270: 17977-17985, 1995.
42. Plata C, Meade P, Hall A, Welch RC, Vazquez N, Hebert SC, and Gamba G. Alternatively spliced isoform of apical Na-K-Cl cotransporter gene encodes a furosemide-sensitive Na-Cl cotransporter. Am J Physiol Renal Physiol 280: F574-F582, 2001.
43. Plata C, Meade P, Vazquez N, Hebert SC, and Gamba G. Functional properties of the apical Na-K-2Cl cotransporter isoforms. J Biol Chem 277: 11004-11012, 2002.
44. Plata C, Mount DB, Rubio V, Hebert SC, and Gamba GG. Isoforms of the Na-K-2Cl cotransporter in murine TAL. II. Functional characterization and activation by cAMP. Am J Physiol Renal Physiol 276: F359-F366, 1999.
45. Race JE, Makhlouf FN, Logue PJ, Wilson FH, Dunham PB, and Holtzman EJ. Molecular cloning and functional characterization of KCC3, a new K-Cl cotransporter. Am J Physiol Cell Physiol 277: C1210-C1219, 1999.
46. Reifarth FW, Amashesh S, Clauss W, and Weber W. The Ca-inactivated Cl channel at work: Selectivity, blocker kinetics and transport visualization. J Membr Biol 155: 95-104, 1997.
47. Schmidt TR, Goodman M, and Grossman LI. Molecular evolution of the COX7A gene family in primates. Mol Biol Evol 16: 619-626, 1999.
48. Schnermann J. Juxtaglomerular cell complex in the regulation of renal salt excretion. Am J Physiol Regul Integr Comp Physiol 274: R263-R279, 1998.
49. Shayakul C, Tsukaguchi H, Berger UV, and Hediger MA. Molecular characterization of a novel urea transporter from kidney inner medullary collecting ducts. Am J Physiol Renal Physiol 280: F487-F494, 2001.
50. Warth R, Bleich M, Thiele I, Lang F, and Greger R. Regulation of the Na-2Cl-K cotransporter in in vitro perfused rectal gland tubules of Squalus acanthias. Pflügers Arch 436: 521-528, 1998.
51. Xu JC, Lytle C, Zhu TT, Payne JA, Benz E, and Forbush B. Molecular cloning and functional expression of the bumetanide-sensitive Na-K-Cl cotransporter. Proc Natl Acad Sci USA 91: 2201-2205, 1994.
52. Yang T, Huang YG, Singh I, Schnermann J, and Briggs JP. Localization of bumetanide- and thiazide-sensitive Na-K-Cl cotransporters along the rat nephron. Am J Physiol Renal Fluid Electrolyte Physiol 271: F931-F932, 1996.
53. Yang Z and Bielawski JP. Statistical methods for detecting molecular adaptation. Trends Ecol Evol 15: 496-506, 2000.