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Volumn 4, Issue 6, 2002, Pages 591-599

High-Throughput Bioassay-Guided Fractionation: A Technique for Rapidly Assigning Observed Activity to Individual Components of Combinatorial Libraries, Screened in HTS Bioassays

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIOASSAY; COMBINATORIAL CHEMISTRY; FRACTIONATION; METHODOLOGY;

EID: 0036831344     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc020042e     Document Type: Article
Times cited : (23)

References (12)
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    • An, H.; Cook, D. A Solution-Phase Combinatorial Chemistry Methodology for Drug Discovery. Recent Res. Dev. Org. Chem. 1998, 2, 473-488.
    • (1998) Recent Res. Dev. Org. Chem. , vol.2 , pp. 473-488
    • An, H.1    Cook, D.2
  • 4
    • 0031828077 scopus 로고    scopus 로고
    • Application of Combinatorial Chemistry to Antimicrobial Drug Discovery
    • Navre, M. Application of Combinatorial Chemistry to Antimicrobial Drug Discovery. Expert Opin. Invest. Drugs 1998, 7, 1257-1269.
    • (1998) Expert Opin. Invest. Drugs , vol.7 , pp. 1257-1269
    • Navre, M.1
  • 5
    • 0033986977 scopus 로고    scopus 로고
    • Use of Genomics and Combinatorial Chemistry in the Development of New Antimycobacterial Drugs
    • Barry, C. E.; Slayden, R. A.; Sampson, A. E.; Lee, R. E. Use of Genomics and Combinatorial Chemistry in the Development of New Antimycobacterial Drugs. Biochem. Pharmacol. 1999, 59, 221-231.
    • (1999) Biochem. Pharmacol. , vol.59 , pp. 221-231
    • Barry, C.E.1    Slayden, R.A.2    Sampson, A.E.3    Lee, R.E.4
  • 6
    • 0033921872 scopus 로고    scopus 로고
    • A Merger of Rational Drug Design and Combintatorial Chemistry: Development and application of peptide secondary structure mimetic
    • Kim, H. O.; Kahn, M. A Merger of Rational Drug Design and Combintatorial Chemistry: development and application of peptide secondary structure mimetic. Comb. Chem. High Throughput Screening 2000, 3, 167-183.
    • (2000) Comb. Chem. High Throughput Screening , vol.3 , pp. 167-183
    • Kim, H.O.1    Kahn, M.2
  • 7
    • 0001532712 scopus 로고    scopus 로고
    • Developments of a Fully Automated Parallel HPLC/Mass Spectrometry System for the Analytical Characterization and Preparative Purification of Combinatorial Libraries
    • Zeng, L.; Kassel, D. B. Developments of a Fully Automated Parallel HPLC/Mass Spectrometry System for the Analytical Characterization and Preparative Purification of Combinatorial Libraries. Anal. Chem. 1998, 70, 4380-4388.
    • (1998) Anal. Chem. , vol.70 , pp. 4380-4388
    • Zeng, L.1    Kassel, D.B.2
  • 9
    • 0035663108 scopus 로고    scopus 로고
    • Isolation of an antimicrobial compound from Impatiens balsamina L. using bioassay-guided fractionation
    • Yang, X.; Summerhurst D. K.; Koval, S. F.; Ficker, C.; Smith, M. L.; Bernards, M. A. Isolation of an antimicrobial compound from Impatiens balsamina L. using bioassay-guided fractionation. Phytother. Res. 2001, 15, 676-680.
    • (2001) Phytother. Res. , vol.15 , pp. 676-680
    • Yang, X.1    Summerhurst, D.K.2    Koval, S.F.3    Ficker, C.4    Smith, M.L.5    Bernards, M.A.6
  • 10
    • 0037731244 scopus 로고    scopus 로고
    • Fernandez, N., Butcher, G., Eds.; IRL Press: Oxford, U.K.
    • Cox, A. L.; Huczko, E. L; Engelhard, V. H.; Shabanowitz, J.; Hunt, D. F. In MHC; Fernandez, N., Butcher, G., Eds.; IRL Press: Oxford, U.K., 1997; Vol. 1, pp 141-160.
    • (1997) MHC , vol.1 , pp. 141-160
    • Cox, A.L.1    Huczko, E.L.2    Engelhard, V.H.3    Shabanowitz, J.4    Hunt, D.F.5
  • 12
    • 0037061628 scopus 로고    scopus 로고
    • A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput screening
    • McGovern, S. L.; Caselli, E.; Grigorieff, N.; Schoichet, B. K. A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput screening. J. Med. Chem. 2002, 45, 1712-1722.
    • (2002) J. Med. Chem. , vol.45 , pp. 1712-1722
    • McGovern, S.L.1    Caselli, E.2    Grigorieff, N.3    Schoichet, B.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.