Antibodies: The laboratory depends on them but they can let us down

Laboratory Medicine

Volumn 33, Issue 11, 2002, Pages 873-876

  McNeely, Michael ^a  

^a MDS Metro Laboratory Services   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; AUTOANTIBODY; BROMOCRIPTINE; CHIMERIC ANTIBODY; CHORIONIC GONADOTROPIN; EPITOPE; ESTRADIOL; HETEROPHILE ANTIBODY; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LEVOTHYROXINE SODIUM; MACROGOL; MONOCLONAL ANTIBODY; OKT 3; PARATHYROID HORMONE; PROLACTIN; PROSTATE SPECIFIC ANTIGEN; REAGENT; RHEUMATOID FACTOR; THYROID ANTIBODY; THYROTROPIN; THYROXINE;

ADULT; AMENORRHEA; ANTIGEN ANTIBODY COMPLEX; ANTIGEN BINDING; ARTICLE; CASE REPORT; CHRONIC KIDNEY FAILURE; CLINICAL FEATURE; CROSS REACTION; DRUG DETERMINATION; ERROR; FEMALE; HORMONE ACTION; HUMAN; HUMAN TISSUE; HYPOTHYROIDISM; IMMUNOASSAY; LABORATORY; MALE; PARATHYROID ADENOMA; PROLACTIN BLOOD LEVEL; PROSTATE ADENOCARCINOMA; RADIOIMMUNOASSAY; RENAL OSTEODYSTROPHY; THYROIDITIS;

EID: 0036828669     PISSN: 00075027     EISSN: None     Source Type: Journal    
DOI: 10.1309/PGVN-0JB1-G96N-FWKT     Document Type: Article

References (15)

1. Ismail AAA, Barth JH. Wrong biochemistry results. BMJ. 2001;323:705-706.
2. Ward G, McKinnon L, Badrick T. et al. Heterophile antibodies remain a problem for the immunoassay laboratory. AJCP. 1997;108:417-421.
3. Kricka LJ. Human anti-animal antibody interferences in immunological assays. Clin Chem. 1999;45:942-956.
4. Birkland D. $16 Million for Misdiagnosis. Seattle Times. June 30, 2001.
5. Kaplan IV, Levinson SS. When is a heterophile antibody not a heterophile antibody? When is it an antibody against a specific immunogen? Clin Chem. 1999;45:616-618.
6. Linstedt G, Nyström E. Ekman R. et al. Information on incidents with consequences for health should be collected centrally. BMJ. 2002;324:422.
7. Kadri N, Douville R Lachance P. Monoclonal paraprotein may interfere with the Roche Direct HDL-C Plus assay. Clin Chem. 2002;48:964.
8. Despres N. Grant N. Antibody interference in thyroid assays: A potential for clinical misinformation. Clin Chem. 1998;44:2557-2559.
9. Schneider W, Marcovitz S, Al-Shammari S, et al. Reactivity of macroprolactin in common automated immunoassays. Clin Biochem. 2001;34:469-473.
10. Vallette-Kasic S, Morange-Ramos I, Adel S, et al. Macroprolactinemia revisited: A study on 106 patients. J Clin Endocrinol Metab. 2002;87:581-588.
11. Leslie H, Courtney CH, Bell PM, et al. Laboratory and clinical experience in 55 patients with macroprolactinemia identified by a simple polyethylene glycol precipitation method. J Clin Endocrinol Metab. 2001;86:2743-2746.
12. Plebani M, Mion M, Altinier S, et al. False positive Troponin I attributed to a macrocomplex. Clin Chem. 2002;48:677-678.
13. Schwartz RH. Urine testing in the detection of drugs of abuse. Arch Intern Med. 1988;148:2407-2412.
14. Valdes R, Jortani SA. Unexpected suppression of immunoassay results from cross-reactivity: Now a demonstrated cause for concern. Clin Chem. 2002;48:405-406.
15. Slatopolsky E, Finch J, Clay P, et al. A novel mechanism for skeletal resistance in uremia. Kidney Intl. 2000;58:753-756.