Reactivity of macroprolactin in common automated immunoassays

Clinical Biochemistry

Volumn 34, Issue 6, 2001, Pages 469-473

  Schneider, Wolfgang ^a   Marcovitz, Sorana ^a   Al Shammari, Sameer ^a   Yago, Silene ^a   Chevalier, Simone ^b  

^a MONTREAL GENERAL HOSPITAL   (Canada)

^b RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

Author keywords

Hyperprolactinemia; Immunoassay; Prolactin; Prolactinoma

Indexed keywords

BUFFER; MACROGOL; MACROPROLACTIN; PROLACTIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CROSS REACTION; DEVICE; EVALUATION; FAST PROTEIN LIQUID CHROMATOGRAPHY; HUMAN; IMMUNOASSAY; INTERMETHOD COMPARISON; MOLECULAR WEIGHT; PRECIPITATION; PRIORITY JOURNAL; QUANTITATIVE ASSAY; SERUM;

AUTOANALYSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FRACTIONAL PRECIPITATION; HUMANS; IMMUNOGLOBULIN G; MOLECULAR WEIGHT; OBSERVER VARIATION; POLYETHYLENE GLYCOLS; PRECIPITATION; PROLACTIN; REFERENCE VALUES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 0034773534     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-9120(01)00256-9     Document Type: Article

References (26)

1. Prolactin and growth hormone: Molecular heterogeneity and measurement in serum
2. Endogenous antibodies against prolactin- a "new" cause of hyperprolactinemia
3. Macroprolactinemia: Contribution to hyperprolactinemia in a district general hospital, and evaluation of a screening test based on precipitation with polyethylene glycol
4. Hyperprolactinemia due to big, big prolactin is differently detected by commercially available immunoassays
5. Macroprolactin reactivities in prolactin assays: An issue for clinical laboratories and equipment manufacturers
6. Frequency of hyperprolactinemia due to large molecular weight prolactin (150-170 kD PRL)
7. Macroprolactin and the Roche Elecsys prolactin assay: Characteristics of the reaction and detection by precipitation with polyethylene glycol
8. Variable detection of macroprolactin; a cause of apparent change in serum prolactin levels
9. Maintained fertility in a patient with hyperprolactinemia due to big, big prolactin
10. Bioactivity of prolactin in a woman with an excess of large molecular size prolactin, persistent hyperprolactinemia and spontaneous conception
11. Characterization of a large molecular weight prolactin in women with idiopathic hyperprolactinemia and normal menses
12. Detailed assessment of big big prolactin in women with hyperprolactinemia and normal ovarian function
13. A normal ovulatory woman with hyperprolactinemia: Presence of anti-prolactin autoantibody and the regulation of prolactin secretion
14. Effects of anti-prolactin autoantibodies on serum prolactin measurements
15. Misleading hyperprolactinemia in pregnancy
16. Some forms of big big prolactin behave as a complex of monomeric prolactin with an immunoglobulin G in patients with macroprolactinemia or prolactinoma
17. Identification of macroprolactin in a patient with asymptomatic hyperprolactinemia as a stable PRL-IgG complex
18. Anti-prolactin (PRL) autoantibodies cause asymptomatic hyperprolactinemia: Bioassay, and clearance studies of PRL-immunoglobulin G complex
19. Macroamylasemia
20. The frequency of macroprolactinemia in pregnant women and the heterogeneity of its etiologies
21. Frequency of macroprolactinemia due to autoantibodies against prolactin in pregnant women
22. Screening for macroprolactinaemia
23. Screening for macroprolactinemia
24. Macroprolactinemia: Validation and application of polyethylene glycol precipitation test and clinical characterization of the condition
25. Extensive experience and validation of polyethylene glycol precipitation as a screening method for macroprolactinemia
26. Prolactin results for samples containing macroprolactin are method and sample dependent