Chemical pregnancies: Immunologic and ultrasonographic studies

American Journal of Reproductive Immunology

Volumn 48, Issue 5, 2002, Pages 323-328

  Coulam, Carolyn B ^a   Roussev, Roumen ^b  

^a Sher Institute for Reproductive Medicine   (United States)

^b NONE

Author keywords

Biochemical pregnancy; Chemical pregnancy; Preclinical pregnancy

Indexed keywords

ANTINUCLEAR ANTIBODY; CHORIONIC GONADOTROPIN; PHOSPHOLIPID ANTIBODY;

ANGIOGENESIS; ARTICLE; BIRTH; CHEMICAL PREGNANCY; COMPARATIVE STUDY; CONTROLLED STUDY; ECTOPIC PREGNANCY; EMBRYO; EMBRYO TRANSFER; EMBRYOTOXICITY; FEMALE; FERTILIZATION IN VITRO; GESTATION PERIOD; GONADOTROPIN BLOOD LEVEL; HUMAN; IMMUNOLOGICAL PARAMETERS; INFERTILITY; MAJOR CLINICAL STUDY; MENSTRUATION; NATURAL KILLER CELL; PREGNANCY; PREGNANCY TEST; PREIMPLANTATION EMBRYO; PREVALENCE; PRIORITY JOURNAL; RISK FACTOR; SPONTANEOUS ABORTION; TRANSVAGINAL ECHOGRAPHY; TREATMENT FAILURE;

ABORTION, HABITUAL; AMNION; ANTIBODIES; FEMALE; FERTILIZATION IN VITRO; HUMANS; PHOSPHOLIPIDS; PREGNANCY; PREGNANCY OUTCOME; RISK FACTORS;

EID: 0036828415     PISSN: 87558920     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0897.2002.01137.x     Document Type: Article

References (31)

1. Clark DA, Lea RG, Podor T, Daya S, Banwatt D, Harley C: Cytokines determining the success or failure of pregnancy. Ann N Y Acad Sci 1991; 626:52-534.
2. Wegmann TG, Lin H, Guilbert L, Mosmann TR: Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon? Immunol Today 1993; 14:353-356.
3. Raghupathy R: Th1 type immunity is incompatible with successful pregnancy. Immunol Today 1997; 18:478-482.
4. Roussev RG, Kaider BD, De Price, Coulam CB: Laboratory evaluation of women experiencing reproductive failure. Am J Reprod Immunol 1996; 34:415-420.
5. Kaider AS, Kaider BD, Janowicz PB, Roussev RG: Immunologic evaluation in women with reproductive failure. Am J Reprod Immunol 1999; 42:335-346.
6. Oh JS, Wright G, Coulam CB: Gestational sac size in very early pregnancy as a predicator of fetal outcome. Ultrasound Obstet Gynecol 2002 (in press).
7. Roussev RG, Stern JJ, Thorsell L, Thomason EJ, Coulam CB: Validation of an embryotoxicity assay. Am J Reprod Immunol 1994; 32:1-5.
8. Coulam CB, Kaider BD, Kaider AS, Janowicz PB, Roussev RG: Antiphospholipid antibodies associated with implantation failure after IVF/ET. J Assist Reprod Genet 1997; 14:603-608.
9. Yetman DL, Kutteh WH: Antiphospholipid antibody panels and recurrent pregnancy loss: prevalence of anticardiolipin antibodies compared with other antiphospholipid antibodies. Fertil Steril 1996; 66:540-546.
10. Rote NS, Vogt E, De Vere G, Obringer AR, Ng AK: The role of placental trophoblast in the pathophysiology of antiphospholipid antibody syndrome. Am J Reprod Immunol 1998; 39:125-136.
11. Kaider BD, Coulam CB, Roussev RG: Murine embryos as a direct target for some human autoantibodies in vitro. Hum Reprod 1999; 14:2556-2561.
12. Azem F, Geva E, Amit A, Lerner-Geva L, Schwartz T, Ben-Yosef D, Yovel I, Lessing JB: High levels of anticardiolipin antibodies in patients with abnormal embryo morphology who attended and in vitro fertilization program. Am J Reprod Immunol 1998; 39:161-163.
13. Rand JH, Wu XX, Andree HAM, Lockwood CJ, Gulles S, Scher J, Harpel PC: Pregnancy loss in the antiphospholipid syndrome - A possible thrombogenic mechanism. N Engl J Med 1997; 337:154-160.
14. Tartakowsky V, Bermos BL, Sthoeger Z, Shearer GM, Mozes E: Defective maternal-fetal interaction in a murine autoimmune model. Hum Reprod 1996; 11:2408-2411.
15. Bach JF, Koutouzou S: New clues to systemic lupus. Lancet 1997; 350:11.
16. Casciola-Rosen L, Anhalt G, Rosen A: Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes. J Exp Med 1994; 179:1317-1330.
17. Casciola-Rosen L, Rosen A, Petri M, Schissel M: Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: Implications for coagulant events in lupus erythematosus. Proc Natl Acad Sci USA 1996; 93: 1624-1692.
18. Coulam CB, Goodman C, Roussev RG, Thomason EJ, Beaman KD: Systemic CD56+ cells can predict pregnancy outcome. Am J Reprod Immunol 1995; 33:40-46.
19. Coulam CB: Implantation failure and immunotherapy. Hum Reprod 1995; 10:1338-1340.
20. Hill JA, Polgar K, Harlow BL, Anderson DJ: Evidence of embryo- and trophoblast-toxic cellular immune response (s) in women with recurrent spontaneous abortion. Am J Obstet Gynecol 1992; 166:1044-1052.
21. Sargent IL, Dorkas A: Embryotoxicity as a marker for recurrent pregnancy loss. Am J Reprod Immunol 1996; 35:383-387.
22. Thomason EJ, Roussev RG, Stern JJ, Coulam CB: Prevalence of embryotoxic factor in sera from women with unexplained recurrent abortion. Am J Reprod Immunol 1995; 34:338-341.
23. Dorkas H, Sargent IL, Redman CWG, Barlow DH: Sera from women with unexplained infertility inhibit both mouse and human embryo growth in vitro. Fertil Steril 1993; 60:285-292.
24. Damewood MD, Heisa JS, Schalff WD, Hubbard M, Gearhart JD, Rock JA: Effect of serum form patients with minimal to mild endometriosis on mouse embryo development in vitro. Fertil Steril 1990; 54:917-920.
25. Folkman J: Tumor angiogenesis: therapeutic implications. N Engl J Med 1971; 285:1182-1186.
26. Salafia C, Maier D, Vogel C, Pezzullo J, Burns J, Silberman L: Placental and decidual pathology in spontaneous abortion: detailed description and correlations with chromosome number. Obstet Gynecol 1993; 82:295-303.
27. Boue J, Boue A, Lazar P: Retrospective and prospective epidemiological studies of 1,500 karyotyped spontaneous human abortions. Teratology 1973; 12:11-26.
28. Clark DA, Chaouat G, Ding JW, August C, Coulam CB, Levy GA: Fgl2 in pregnancy: a novel prothrombinase at the fetomaternal interface mat prevent bleeding and cause abortions. Am J Reprod Immunol 1999; 41:374-379.
29. Clark DA, Chaouat G, Arck PC, Mittruecker HW, Levy GA: The cutting edge: cytokine dependent abortion in CBA × DBA/2 mice is mediated by the procoagulant fgl2 prothrombinase. J Immunol 1998; 160:545-549.
30. Verlinsky Y, Cieslak J, Ivakhnenko V, Evsikov S, Wolf G, White M, Lifchez A, Kaplan B, Moise J, Valle J, Ginsberg N, Strom C, Kukliev A: Prevention of age related aneuploidies by polar body testing of oocytes. J Assist Reprod Genet 1999; 16:165-169.
31. Munne S, Magit C, Cohen J, Morton P, Safowy S, Gianaroli L, Tucker M, Marquez C, Sable D, Ferrareti AP, Massey JB, Scott R: Positive outcome after preimplantation diagnosis of aneuploidy in human embryos. Hum Reprod 1999; 14:2191-2199.