Reduced liver uptake of arterially infused melphalan during retrograde rat liver perfusion with unaffected liver tumor uptake

Journal of Pharmacology and Experimental Therapeutics

Volumn 303, Issue 2, 2002, Pages 736-740

  Rothbarth, Joost ^a   Sparidans, Rolf W ^a   Beijnen, Jos H ^a,b   Schultze Kool, Leo J ^a,d   Putter, Hein ^b   Van De Velde, Cornelis J H ^d   Mulder, Gerard J ^c  

^a Department of Surgery ^*  (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c LEIDEN UNIVERSITY   (Netherlands)

^d UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

MELPHALAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG INFUSION; DRUG TISSUE LEVEL; DRUG UPTAKE; HEPATIC ARTERY; ISOLATED LIVER; LIVER PERFUSION; LIVER TOXICITY; LIVER TUMOR; NONHUMAN; PRIORITY JOURNAL; RAT; STEADY STATE;

ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HEPATIC ARTERY; INFUSIONS, INTRAVENOUS; LIVER; LIVER NEOPLASMS; MALE; MELPHALAN; NEOPLASM TRANSPLANTATION; PERFUSION; RATS; RATS, INBRED STRAINS;

EID: 0036827912     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.037895     Document Type: Article

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