Of mice and men, and cancer research

Drug Discovery Today

Volumn 7, Issue 19, 2002, Pages 981-982

  Habeck, Martina ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RAF PROTEIN;

CANCER RESEARCH; HUMAN; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; ONCOGENE RAS; PROTEIN BINDING; PROTEIN FUNCTION; SHORT SURVEY; SIGNAL TRANSDUCTION;

ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; HUMANS; MICE; NEOPLASMS; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 0036807210     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(02)02459-5     Document Type: Short Survey

References (6)

1. Hamad N.M., et al. Distinct requirements for Ras oncogenesis in human versus mouse cells. Genes Dev. 16:2002;2045-2057.
2. Campbell S.L., et al. Increasing complexity of Ras signaling. Oncogene. 17:1998;1395-1413.
3. Hahn W.C., et al. Creation of human tumour cells with defined genetic elements. Nature. 400:1999;464-468.
4. Hahn W.C., et al. Enumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol. Cell Biol. 22:2002;2111-2123.
5. Shields J., et al. Understanding Ras function: 'it ain't over 'til it's over'. Trends Cell Biol. 10:2000;147-154.
6. Davies H., et al. Mutations of the BRAF gene in human cancer. Nature. 417:2002;949-954.