Neural and marrow-derived stromal cell sphere transplantation in a rat model of traumatic brain injury

Journal of Neurosurgery

Volumn 97, Issue 4, 2002, Pages 935-940

  Lu, Dunyue ^a   Li, Yi ^a   Mahmood, Asim ^a   Wang, Lei ^a   Rafiq, Tahir ^a   Chopp, Michael ^a  

^a HENRY FORD HOSPITAL   (United States)

Author keywords

Rat; Transplantation; Traumatic brain injury

Indexed keywords

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; BRAIN INJURY; CELL TRANSPLANTATION; COMPOSITE MATERIAL; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; IMAGE ANALYSIS; MALE; NONHUMAN; PHASE CONTRAST MICROSCOPY; PRIORITY JOURNAL; RAT; STROMA CELL;

EID: 0036802148     PISSN: 00223085     EISSN: None     Source Type: Journal    
DOI: 10.3171/jns.2002.97.4.0935     Document Type: Article

References (29)

1. Bi LX, Simmons DJ, Mainous E: Expression of BMP-2 by rat bone marrow stromal cells in culture. Calcif Tissue Int 64:63-68, 1999
2. Brazelton TR, Rossi FM, Keshet GI, et al: From marrow to brain: Expression of neuronal phenotypes in adult mice. Science 290:1775-1779, 2000
3. Brundin P, Karlsson J, Emgard M, et al: Improving the survival of grafted dopaminergic neurons: A review over current approaches. Cell Transplant 9:179-195, 2000
4. Caneva L, Soligo D, Cattoretti G, et al: Immuno-electron microscopy characterization of human bone marrow stromal cells with anti-NGFR antibodies. Blood Cells Mol Dis 21:73-85, 1995
5. Dixon CE, Clifton GL, Lighthall JW, et al: A controlled cortical impact model of traumatic brain injury in the rat. J Neurosci Methods 39:253-262, 1991
6. Gressens P: Mechanisms and disturbances of neuronal migration. Pediatr Res 48:725-730, 2000
7. Hamm RJ, Pike BR, O'Dell DM, et al: The rotarod test: An evaluation of its effectiveness in assessing motor deficits following traumatic brain injury. J Neurotrauma 11:187-196, 1994
8. Iwashita Y, Kawaguchi S, Murata M: Restoration of function by replacement of spinal cord segments in the rat. Nature 367:167-170, 1994
9. Kaddis FG, Clarkson ED, Bell KP, et al: Co-grafts of muscle cells and mesencephalic tissue into hemiparkinsonian rats: Behavioral and histochemical effects. Brain Res Bull 51:203-211, 2000
10. Kesslak JP, Brown L, Steichen BC, et al: Adult and embryonic frontal cortex transplants after frontal cortex ablation enhance recovery on a reinforced alternation task. Exp Neurol 94:615-626, 1986
11. Kesslak JP, Nieto-Sampedro M, Globus J, et al: Transplants of purified astrocytes promote behavioral recovery after frontal cortex ablation. Exp Neurol 92:377-390, 1986
12. Kopen GC, Prockop DJ, Phinney DG: Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains. Proc Natl Acad Sci USA 96:10711-10716, 1999
13. Laurenzi MA, Beccari T, Stenke L, et al: Expression of mRNA encoding neurotrophins and neurotrophin receptors in human granulocytes and bone marrow cells - Enhanced neurotrophin-4 expression induced by LTB4. J Leukoc Biol 64:228-234, 1998
14. Lu D, Mahmood A, Wang L, et al: Adult bone marrow stromal cells administered intravenously to rats after traumatic brain injury migrate into brain and improve neurological outcome. Neuroreport 12:559-563, 2001
15. Mahmood A, Lu D, Wang L, et al: Treatment of traumatic brain injury in female rats with intravenous administration of bone marrow stromal cells. Neurosurgery 49:1196-1204, 2001
16. Mezey E, Chandross KJ, Harta G, et al: Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow. Science 290:1779-1782, 2000
17. Muir JK, Raghupathi R, Saatman KE, et al: Terminally differentiated human neurons survive and integrate following transplantation into the traumatically injured rat brain. J Neurotrauma 16:403-414, 1999
18. Netto CA, Hodges H, Sinden JD, et al: Foetal grafts from hippocampal region superior alleviate ischemic-induced behavioural deficits. Behav Brain Res 58:107-112, 1993
19. Park KI, Liu S, Flax JD, et al: Transplantation of neural progenitor and stem cells: Developmental insights may suggest new therapies for spinal cord and other CNS dysfunction. J Neurotrauma 16:675-687, 1999
20. Park KW, Eglitis MA, Mouradian MM: Protection of nigral neurons by GDNF-engineered marrow cell transplantation. Neurosci Res 40:315-323, 2001
21. Shohami E, Novikov M, Bass R: Long-term effect of HU-211, a novel non-competitive NMDA antagonist, on motor and memory functions after closed head injury in the rat. Brain Res 674:55-62, 1995
22. Sinson G, Voddi M, McIntosh TK: Combined fetal neural transplantation and nerve growth factor infusion: Effects on neurological outcome following fluid-percussion brain injury in the rat. J Neurosurg 84:655-662, 1996
23. Stein DG, Palatucci C, Kahn D, et al: Temporal factors influence recovery of function after embryonic brain tissue transplants in adult rats with frontal cortex lesions. Behav Neurosci 102:260-267, 1988
24. Subramanian T: Cell transplantation for the treatment of Parkinson's disease. Semin Neurol 21:103-115, 2001
25. Tomita S, Li RK, Weisel RD, et al: Autologous transplantation of bone marrow cells improves damaged heart function. Circulation 100 (Suppl 19):II247-II254, 1999
26. Wictorin K, Brundin P, Sauer H, et al: Long distance directed axonal growth from human dopaminergic mesencephalic neuroblasts implanted along the nigrostriatal pathway in 6-hydroxydopamine lesioned adult rats. J Comp Neurol 323:475-494, 1992
27. Yurek DM, Seroogy KB: Differential expression of neurotrophin and neurotrophin receptor mRNAs in and adjacent to fetal midbrain grafts implanted into the dopamine-denervated striatum. J Comp Neurol 423:462-473, 2000
28. Zhang ZG, Chopp M, Goussev A, et al: Cerebral microvascular obstruction by fibrin is associated with upregulation of PAI-1 acutely after onset of focal embolic ischemia in rats. J Neurosci 19:10898-10907, 1999
29. Zurita M, Vaquero J, Oya S, et al: Functional recovery in chronic paraplegic rats after co-grafts of fetal brain and adult peripheral nerve tissue. Surg Neurol 55:249-255, 2001