Ventilator-associated pneumonia and ventilator-induced lung injury: Two peas in a pod

Critical Care Medicine

Volumn 30, Issue 10, 2002, Pages 2391-2392

  Kollef, Marin ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acute lung injury; Mechanical ventilation; Pneumonia; Translocation

Indexed keywords

ADULT RESPIRATORY DISTRESS SYNDROME; ARTIFICIAL VENTILATION; BACTEREMIA; BACTERIAL TRANSLOCATION; EDITORIAL; ENTEROBACTER AEROGENES; HEMODYNAMICS; IMMUNE RESPONSE; LUNG INFECTION; LUNG INJURY; LUNG PRESSURE; NONHUMAN; PNEUMONIA; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; RABBIT;

EID: 0036799506     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200210000-00041     Document Type: Editorial

References (12)

1. Charles PE, Piroth L, Desbiolles N, et al: New model of ventilator-associated pneumonia in immunocompetent rabbits. Crit Care Med 2002; 30:2278-2283
2. Nahum A, Hoyt J, Schmitz L, et al: Effect of mechanical ventilation strategy on dissemination of intratracheally instilled Escherichia coli in dogs. Crit Care Med 1997; 25:1733-1743
3. Kollef MH, Eisenberg PR, Ohlendorf MF, et al: The accuracy of elevated concentrations of endotoxin in bronchoalveolar lavage fluid for the rapid diagnosis of Gram-negative pneumonia. Am J Respir Crit Care Med 1996; 154:1020-1028
4. Murphy DB, Cregg N, Tremblay L, et al: Adverse ventilatory strategy causes pulmonary-to-systemic translocation of endotoxin. Am J Respir Crit Care Med 2000; 162:27-33
5. Ranieri VM, Suter P, Tortorella C, et al: Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: A randomized controlled trial. JAMA 1999; 282:54-61
6. Amato MB, Barbas CS, Medeiros DM, et al: Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med 1998; 338:347-354
7. Brower RG, Matthay MA, Morris A, et al: Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000; 342:1301-1308
8. Delclaux C, Roupie E, Blot F, et al: Lower respiratory tract colonization and infection during severe acute respiratory distress syndrome: Incidence and diagnosis. Am J Respir Crit Care Med 1997; 156:1092-1098
9. Markowicz P, Wolff M, Djedaini K, et al: Multicenter prospective study of ventilator-associated pneumonia during acute respiratory distress syndrome: Incidence, prognosis, and risk factors. Am J Respir Crit Care Med 2000; 161:1942-1948
10. Olsen ME, Harmon BG, Kollef MH: Silvercoated endotracheal tubes associated with reduced ventilator-associated pneumonia (VAP) in dogs. Chest 2002; 121:863-870
11. Bergmans DC, Bonten MJ, Gaillard CA, et al: Prevention of ventilator-associated pneumonia by oral decontamination: A prospective, randomized, double-blind, placebo-controlled study. Am J Respir Crit Care Med 2001; 164:382-388
12. Martinez-Pellus AE, Merino P, Bru M, et al: Can selective digestive decontamination avoid the endotoxemia and cytokine activation promoted by cardiopulmonary bypass? Crit Care Med 1993; 21:1684-1691