Influence of age on immune changes in runners after a marathon

Journal of Aging and Physical Activity

Volumn 10, Issue 4, 2002, Pages 432-442

  Pistilli, Edward E ^a   Nieman, David C ^a   Henson, Dru A ^a   Kaminsky, David E ^a   Utter, Alan C ^a   Vinci, Debra M ^a   Davis, J Mark ^b   Fagoaga, Omar R ^c   Nehlsen Cannarella, Sandra L ^c  

^a APPALACHIAN STATE UNIVERSITY   (United States)

^b UNIVERSITY OF SOUTH CAROLINA   (United States)

^c LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Catecholamines; Cytokines; Lymphocytes; Salivary IgA

Indexed keywords

ADRENALIN; GROWTH HORMONE; HYDROCORTISONE; IMMUNOGLOBULIN A; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8;

ADRENALIN BLOOD LEVEL; ADULT; AGE; AGING; ARTICLE; BLOOD SAMPLING; FEMALE; GROWTH HORMONE BLOOD LEVEL; HORMONAL REGULATION; HUMAN; HUMAN EXPERIMENT; HYDROCORTISONE BLOOD LEVEL; IMMUNE STATUS; IMMUNOGLOBULIN PRODUCTION; LEUKOCYTE; LYMPHOCYTE COUNT; MALE; MARATHON RUNNER; NORMAL HUMAN; RUNNING; T LYMPHOCYTE;

EID: 0036797818     PISSN: 10638652     EISSN: None     Source Type: Journal    
DOI: 10.1123/japa.10.4.432     Document Type: Article

References (31)

1. Belcastro, A.N., Arthurn, G.D., Albisser, T.A., & Raj, DA. (1996). Heart, liver, and skeletal muscle myeloperoxidase activity during exercise. Journal of Applied Physiology, 80, 1331-1335.
2. Blanin, A.K., Robson, P.J., Walsh, N.P., Clark, A.M., Glennon, L., & Gleeson, M. (1998). The effect of exercising to exhaustion at different intensities on saliva immunoglobulin A, protein and electrolyte secretion. International Journal of Sports Medicine, 19, 547-552.
3. Bradford, M.M. (1976). A rapid and sensitive method for the quantitation of microgram quantities protein utilizing the principle of protein-dye binding. Annals of Biochemistry, 72, 248-254.
4. Bruunsgaard, H., Jensen, M.S., Schjerling, P., Halkjaer-Kristensen, J., Ogawa, K., Shinhoj, P., & Pedersen, B.K. (1999). Exercise induces recruitment of lymphocytes with an activated phenotype and short telomeres in young and elderly humans. Life Science, 65, 2623-2633.
5. Ceddia, M.A., Price, E.A., Kohlmeier, C.K., Evans, J.F., Lu, Q., McAuley, E., & Woods, J.A. (1999). Differential leukocytosis and lymphocyte mitogenic response to acute maximal exercise in the young and old. Medicine and Science in Sports and Exercise, 31, 829-836.
6. Dill, D.B., & Costill, D.L. (1974). Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration. Journal of Applied Physiology, 37, 247-248.
7. Drenth, J.P., Van Uum, S.H.M., Van Deuren, M., Pesman, G.J., Van Der VenJongekrijg, J., & Van Der Meer, J.W.M. (1995). Endurance run increases circulating IL-6 and IL-1ra but down regulates ex vivo TNFα and IL-1β production. Journal of Applied Physiology, 79, 1497-1503.
8. Fahey, J.L., Schnelle, J.F., Boscardin, J., Thomas, J.K., Gorre, M.E., Aziz, N., et al. (2000). Distinct categories of immunologic changes in frail elderly. Mechanisms of Ageing and Development, 115, 1-20.
9. Ginaldi, L., De Martinis, M., D'Ostilio, A., Marini, L., Loreto, M.F., Corsi, M.P., & Quaglino, D. (1999a). The immune system in the elderly: I. Specific humoral immunity. Immunology Research, 20, 101-108.
10. Ginaldi, L., De Martinis, M., D'Ostilio, A., Marini, L., Loreto, M.F., Martorelli, V., & Quaglino, D. (1999b). The immune system in the elderly: II. Specific cellular immunity. Immunology Research, 20, 109-115.
11. Ginaldi, L., De Martinis, M., D'Ostilio, A., Marini, L., Loreto, M.F., & Quaglino, D. (1999c). The immune system in the elderly: III. Innate immunity. Immunology Research, 20, 117-126.
12. Gleeson, M. (2000). Mucosal immunity and respiratory illness in elite athletes. International Journal of Sports Medicine, 21(suppl 1), S33-S43.
13. Gleeson, M., Hall, S.T., McDonald, W.A., Flanagan, A.J., & Clancy, R.L. (1999). Salivary IgA subclasses and infection risk in elite swimmers. Immunology and Cell Biology, 77, 351-355.
14. Gleeson, M., McDonald, W.A., Pyne, D.B., Clancy, R.L., Cripps, A.W., Francis, J.L., & Fricker, P.A. (2000). Immune status and respiratory illness for elite swimmers during a 12-week training cycle. International Journal of Sports Medicine, 21, 302-307.
15. Han, S.J., & Meydani, S.N. (2000). Antioxidants, cytokines, and influenza infection in aged mice and elderly humans. Journal of Infectious Disease, 182(suppl 1), S74-S80.
16. Hasegawa, Y., Sawada, M., Ozaki, N., Inagaki, T., & Suzumura, A. (2000). Increased soluble tumor necrosis factor receptor levels in the serum of elderly people. Gerontology, 46, 185-188.
17. Jemmott, J.B., & McClelland, D.C. (1989). Secretory IgA as a measure of resistance to infectious disease: Comments on Stone, Cox, Valdimarsdottir, and Neale. Behavioral Medicine, 15, 63-71.
18. Miletic, I.D., Schiffman, S.S., Miletic, V.D., & Sattely-Miller, E.A. (1996). Salivary IgA secretion rate in young and elderly persons. Physiology and Behavior, 60, 243-248.
19. Müns, G., Liesen, H., Riedel, H., & Bergmann, K-C. (1989). Einfluß von langstreckenlauf auf den IgA-gehalt in nasensekret und speichel. Deutsche Zeitschrift für Sportmedizin, 40, 63-65.
20. Nehlsen-Cannarella, S.L., Fagoaga, O.R., Nieman, D.C., Henson, D.A., Butterworth, D.E., Schmitt, R.L., et al. (1997). Carbohydrate and the cytokine response to 2.5 hours of running. Journal of Applied Physiology, 82, 1662-1667.
21. Nieman, D.C. (1997). Immune response to heavy exertion. Journal of Applied Physiology, 82, 1385-1394.
22. Nieman, D.C. (1999). Exercise testing and prescription: A health-related approach. Mountain View, CA: Mayfield.
23. Nieman, D.C. (2000). Exercise effects on systemic immunity. Immunology and Cell Biology, 78, 496-501.
24. Nieman, D.C. (2001). Influence of physical activity in immunesenescence. In K. Shiraki, S. Sagawa, & M.K. Yousef (Eds.), Physical fitness and health promotion in active aging (pp. 165-173). Leiden, The Netherlands: Backhuys.
25. Nieman, D.C., Henson, D.A., Gusewitch, G., Warren, B.J., Dotson, R.C., Butterworth, D.E., & Nehlsen-Cannarella, S.L. (1993). Physical activity and immune function in elderly women. Medicine and Science in Sports and Exercise, 25, 823-831.
26. Nieman, D.C., Henson, D.A., Smith, L.L., Utter, A.C., Vinci, D.M., Davis, J.M., et al. (2001). Cytokine changes after a marathon race. Journal of Applied Physiology, 91, 109-114.
27. Shinkai, S., Kohno, H., Kimura, K., Komura, T., Asai, H., Inai, R., et al. (1995). Physical activity and immune senescence in men. Medicine and Science in Sports and Exercise, 27, 1516-1526.
28. Shinkai, S., Konishi, M., & Shephard, R.J. (1998). Aging and the immune response to exercise. Canadian Journal of Physiology and Pharmacology, 76, 562-572.
29. Steerenberg, P.A., van Asperen, I.A., van Nieuw Amerongen, A., Biewenga, A., Mol, D., & Medema, G.J. (1997). Salivary levels of immunoglobulin A in triathletes. European Journal of Oral Science, 105, 305-309.
30. Straub, R.H., Miller, L.E., Scholmerich, J., & Zietz, B. (2000). Cytokines and hormones as possible links between endocrinosenescence and immunosenescence. Journal of Neuroimmunology, 109, 10-15.
31. Woods, J.A., Evans, J.K., Wolters, B.W., Ceddia, M.A., & McAuley, E. (1998). Effects of maximal exercise on natural killer (NK) cell cytotoxicity and responsiveness to interferon-α in the young and old. Journal of Gerontology: Biological Sciences, 53A, B430-B437.