Does reduced DNA repair capacity play a role in HIV infection and progression in the lymphocytes of opiate addicts?

Journal of Acquired Immune Deficiency Syndromes

Volumn 31, Issue SUPPL. 2, 2002, Pages

  Madden, John J ^a,b   Wang, Yichong ^a   Lankford Turner, Pamela ^a   Donahoe, Robert M ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE   (United States)

Author keywords

AIDS; DNA repair; HIV 1 mutation; Opiates; UV radiation

Indexed keywords

ANTIRETROVIRUS AGENT; COCAINE; DNA; OPIATE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; COCAINE DEPENDENCE; CONFERENCE PAPER; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; GENE MUTATION; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE; OPIATE ADDICTION; PRIORITY JOURNAL; VIRUS GENOME; VIRUS INFECTION;

EID: 0036797379     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/00126334-200210012-00008     Document Type: Conference Paper

References (41)

1. Lehman AR. Replication of UV-damaged DNA: new insights into the links between DNA polymerases, mutagenesis and human disease. Gene 2000;253:1-12.
2. Nakagawa A, Kobayashi N, Muramatsu T, et al. Three-dimensional visualization of UV-induced DNA damage and its repair in human cell nuclei. J Invest Dermatol 1998;110:143-8.
3. Bernburg M, Krutmann J. Photoimmunology, DNA repair and photocarcinogenesis. J Photochem Photobiol B 2000;54:87-93.
4. Celotti L, Ferraro P, Biasin MR. Detection by fluorescence analysis of DNA unwinding and unscheduled DNA synthesis of DNA damage and repair induced in vitro by direct-acting mutagens on human lymphocytes. Mutat Res 1992;281:17-23.
5. Lewensohn R, Ringborg U, Baral E, et al. DNA repair synthesis in sub-populations of human lymphocytes. J Cell Sci 1982;54:69-78.
6. Knudsen LE, Ryder LP, Wassermann K. Induction of DNA repair synthesis in human monocytes/B lymphocytes compared with T lymphocytes after exposure to AAAF and dimethylsulfate in vitro. Carcinogenesis 1992;13:1285-7.
7. Madden JJ, Falek A, Shafer DA, et al. Effects of opiates and demographic factors on DNA repair synthesis in human leukocytes. Proc Natl Acad Sci USA 1979;76:5769-73.
8. Pero RW, Ostlund C. Direct comparisons, in human resting lymphocytes, of the inter-individual variations in unscheduled DNS synthesis induced by AAAF and UV. Murat Res 1980;73:349-61.
9. Bender MA, Setlow RB. Spontaneous and induced micronuclei and UDS in peripheral lymphocytes. Murat Res 1994;313:209-14.
10. Risom L, Knudsen LE. Use of cryopreserved peripheral mononuclear blood cells in biomonitoring. Murat Res 1999;440:131-8.
11. Madden JJ, Falek A, Shafer DA, et al. Influence of demographic factors on unscheduled DNA synthesis as measured in human peripheral leukocytes and fibroblasts. In deSerres FJ, Pero RW, eds. Individual susceptibility to genotoxic agents in the human population. 1984:359-71.
12. Moller P, Knudsen LE, Frentz G, et al. Seasonal variation of DNA damage and repair in patients with non-melanoma skin cancer and referents with and without psoriasis. Mutat Res 1998;407:25-34.
13. Schmitz C, Axmacher B, Zunker U, et al. Age-related changes of DNA repair and mitochondrial DNA synthesis in mouse brain. Acta Neuropathol (Berl) 1999;97:71-81.
14. Alrefai RH, Beecham EJ, Bohr VA, et al. Less repair of pyrimidine dimers and single-strand breaks in genes by SCID cells. Biochem Biophys Res Commun 1999;264:878-82.
15. Sims JL, Berger SJ, Berger NA. Effects of nicotinamide on NAD and poly(ADP-ribose) metabolism in DNA damaged human lymphocytes. J Supramol Struct Cell Biochem 1981;16:281-8.
16. Stierum RH, van Herwijnen MH, Hageman GJ, et al. Increased poly(ADP-ribose) polymerase activity during repair of (+/-)-antibenzo[a]pyrene diolepoxide-induced DNA damage in human peripheral blood lymphocytes in vitro. Carcinogenesis 1994;15:745-51.
17. Groisman IJ, Koshy R, Henkler F, et al. Downregulation of DNA excision repair by hepatitis B virus-x protein occurs in p53 proficient and p53 deficient cells. Carcinogenesis 1999;20:479-83.
18. Zhu Q, Wani MA, El-Mahdy M, et al. Modulation of transcriptional activity of p53 by UV radiation: linkage between p53 pathway and DNA repair through damage recognition. Mol Carcinog 2000;28:215-24.
19. Smith ML, Ford JM, Hollander MC, et al. P53-mediated DNA repair responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd 45 genes. Mol Cell Biol 2000;20:3705-14.
20. Yen L, Nie ZR, You XL, et al. Regulation of cellular response to cisplatin-induced DNA damage and DNA repair in cells overexpressing p185(erbB-2) is dependent on the ras signaling pathway. Oncogene 1997;14:1827-35.
21. Chang LC, Sheu HM, Huang YS, et al. A novel function of emodin: enhancement of nucleotide excision repair of UV- and cisplatin-induced DNA damage in human cells. Biochem Pharmacol 1999;58:49-57.
22. Gensler HL, Lindberg RE, Pinnas JL, et al. Deficiency of UV-induced excision repair in human thymocytes. Leuk Res 1983;9:471-9.
23. Shafer DA, Falek A, Madden JJ. Parallel increases in sister-chromatid exchanges at base level and with UV treatment in human opiate users. Murat Res 1983;109:73-82.
24. Sawant SG, Couch DB. Induction of micronuclei in murine lymphocytes by morphine. Environ Mol Mutagen 1995;25:279-83.
25. Couch DB, Sawant SG. The clastogenicity of morphine sulfate in vivo. Adv Exp Med Biol 1995;373:123-9.
26. Brusick D, Matheson D, Jagannath D, et al. Genetic screening of compounds used in drug abuse treatment. II. Methadone. Drug Chem Toxicol 1981;4:1-18.
27. Brusick D, Matheson D, Jagannath D, et al. Genetic screening of compounds used in drug abuse treatment. III. LAAM. Drug Chem Toxicol 1981;4:19-35.
28. Shafer D, Xie Y, Falek A. Detection of opiate-enhanced increases in DNA damage, HPRT mutants, and mutation frequency in human HUT-78 cells. Environ Mol Mutagen 1994;23:37-44.
29. Osugi T, Ding Y, Tanaka H, et al. Involvement of a single-stranded DNA binding protein, ssCRE-BP/Pur alpha, in morphine dependence. FEBS Lett 1996;391:11-6.
30. Ding Y, Osugi T, Tanaka H, et al. Characterization of a nuclear factor that enhances DNA binding activity of SSCRE-BP/PUR alpha, a single-stranded DNA binding protein. Neurochem Int 1997;31:45-54.
31. Maneckjee R, Minna JD. Opioids induce while nicotine suppresses apoptosis in human lung cancer cells. Cell Growth Differ 1994;5:1033-40.
32. Kugawa F, Area K, Ueno A, et al. Buprenorphine hydrochloride induces apoptosis in NG108-15 nerve cells. Eur J Pharmacol 1998;347:105-12.
33. Fuchs BA, Pruett SB. Morphine induces apoptosis in murine thymocytes in vivo but not in vitro: involvement of both opiate and glucocorticoid receptors. J Pharmacol Exp Ther 1993;266:417-23.
34. Weinstock H, Respess R, Heneine W, et al. Prevalence of mutations associated with reduced antiretroviral drug susceptibility among human immunodeficiency virus type 1 seroconverters in the United States, 1993-98. J Infect Dis 2000;182:330-3.
35. Clarke JR, Kaye S, Babiker AG, et al. Comparison of a point mutation assay with a line probe assay for the detection of major mutations in the HIV-1 reverse transcriptase gene associated with reduced susceptibility to nucleoside analogues. J Virol Methods 2000;88:117-24.
36. Ross L, Johnson M, DeMasi R, et al. Viral genetic heterogeneity in HIV-1-infected individuals is associated with increasing use of HAART and higher viremia. AIDS 2000;14:813-9.
37. Paolucci S, Baldanti M, Maserati Castelli F, et al. Quantification of the impact of HIV-1 reverse transcriptase and protease mutations on the efficacy of rescue HAART. Antiviral Res 2000;45:101-14.
38. Bacheler LT, Anton ED, Kudish P, et al. HIV-1 mutations selected in patients failing efavirenz combination therapy. Antimicrob Agents Chemother 2000;44:2475-84.
39. Shah FS, Curr KA, Hamburgh ME, et al. Differential influence of nucleoside analog-resistance mutations K65R and L74V on the overall mutation rate and error specificity of HIV-1 reverse transcriptase. J Biol Chem 2000;275:27037-44.
40. Mansky LM, Bernard LC. 3′-Azido-3′-deoxythymidine (AZT and AZT-resistant reverse transcriptase can increase the in vivo mutation rate of HIV-1. J Virol 2000;74:9532-9.
41. Mansky LM, Preveral S, Selig L, et al. The interaction of vpr with uracil DNA glycosylase modulates the HIV-1 in vivo mutation rate, J Virol 2000;74:7039-47.