Age- and diet-related increase in transepithelial colon permeability of Fischer 344 rats

Digestive Diseases and Sciences

Volumn 47, Issue 10, 2002, Pages 2262-2270

  Mullin, J M ^a   Valenzano, M C ^a   Verrecchio, J J ^a   Kothari, R ^a  

^a LANKENAU HOSPITAL   (United States)

Author keywords

Epithelia; Paracellular; Phorbol ester; Protein kinase C; Tight junction

Indexed keywords

MANNITOL; PHORBOL ESTER;

AGE; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLON CANCER; CONTROLLED STUDY; DESCENDING COLON; DIETARY INTAKE; DISEASE MODEL; DISTANCE PERCEPTION; ELECTRIC RESISTANCE; EPITHELIUM CELL; EVALUATION; FAT INTAKE; INTESTINE MUCOSA PERMEABILITY; MALE; NONHUMAN; PATHOLOGICAL ANATOMY; PRIORITY JOURNAL; RAT;

AGING; ANIMALS; CELL MEMBRANE PERMEABILITY; COLON; DIETARY FATS; DIFFUSION; FOOD HABITS; HUMANS; INTESTINAL MUCOSA; MALE; MANNITOL; MEMBRANE POTENTIALS; PHORBOL 12,13-DIBUTYRATE; RATS; RATS, INBRED F344;

EID: 0036796922     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1020191412285     Document Type: Article

References (39)

1. Fraumeni JF, Hoover RN, Devesa SS, Kinlen JL: Epidemiology of cancer. In Cancer: Principles and Practice of Oncology. VT Devita, Jr, S Hellmann, SA Rosenberg (eds.), Philadelphia, JB Lippincott, 1993, pp 150-181
2. Karczewski J, Groot J: Molecular physiology and pathophysiology of tight junctions III. Tight junction regulation by intracellular messengers: differences in response within and between epithelia. Am J Physiol Gastrointest Liver Physiol 279:G660-G665, 2000
3. Nusrat A, Chen JA, Foley CS, Liang TW, Tom J, Cromwell M, Quan C and Mrsny RJ: The coiled-coil domain of occludin can act to organize structural and functional elements of the epithelial tight junction. J Biol Chem 275:29816-29822, 2000
4. Mitic LL, Van Itallie CM, Anderson JM: Molecular physiology and pathophysiology of tight junctions I. Tight junction structure and function: lessons from mutant animals and proteins. Am J Physiol Gastrointest Liver Physiol 279:G250-G254, 2000
5. Schneeberger EE, Lynch RD: Structure, function, and regulation of cellular tight junctions. Am J Physiol Lung Cell Mol Physiol 262:L647-L661, 1992
6. Patterson WB: Cancer in older people: an overview. In Oxford Textbook of Geriatric Medicine. JG Evans and TF Williams (eds). Oxford, Oxford University Press, 1992, pp 287
7. Roncucci L, Pedroni M, Vaccina F, Benatti P, Marzona L, De Pol A: Aberrant crypt foci in colorectal carcinogenesis. Cell and crypt dynamics. Cell Prolif 33:1-18, 2000
8. Klurfeld DM, Bull AW: Fatty acids and colon cancer in experimental models. Am J Clin Nutr 66:1530S-1538S, 1997
9. Baird AW: Regulation of chloride secretion in mammalian colon. Ir J Med Sci 163:277-281, 1994
10. Wills NK, Lewis SA, Eaton DC: Active and passive properties of rabbit descending colon: a microelectrode and nystatin study. J Membr Biol 45:81-108, 1979
11. Agarwal R, Afzalpurkar R, Fordtran JS: Pathophysiology of potassium absorption and secretion by the human intestine. Gastroenterology 107:548-571, 1994
12. Ojakian GK: Tumor promoter-induced changes in the permeability of epithelial cell tight junctions. Cell 23:95-103, 1981
13. Mullin JM, O'Brien TG: Effects of tumor promoters on LLC-PK1 renal epithelial tight junctions and transepithelial fluxes. Am J Physiol 251:C597-C602, 1986
14. 2+: a protein kinase C effect. J Membr Biol 149:71-79, 1996
15. Hecht G, Robinson B, Koutsouris A: Reversible disassembly of an intestinal epithelial monolayer by prolonged exposure to phorbol ester. Am J Physiol Gastrointest Liver Physiol 266:G214-G221, 1994
16. Donowitz M, Cheng HY and Sharp GW: Effects of phorbol esters on sodium and chloride transport in rat colon. Am J Physiol 251:G509-G517, 1986
17. Civan MM, Rubenstein D, Mauro T, O'Brien TG: Effects of tumor promoters on sodium ion transport across frog skin. Am J Physiol 248:C457-C465, 1985
18. Clandinin MT, Jumpsen J, Suh M: Relationship between fatty acid accretion, membrane composition, and biologic functions. J Pediatr 125:S25-S32, 1994
19. Clandinin MT, Cheema S, Field CJ, Baracos VE: Dietary lipids influence insulin action. Ann NY Acad Sci. 683:151-163, 1993
20. Newton AC: Protein kinase C: structure, function, and regulation. J Biol Chem 270:28495, 1995
21. Nishizuka Y: The role of protein kinase C in cell surface signal transduction and tumour promotion. Nature. 308:693-698, 1984
22. Hasegawa H, Fujita H, Katoh H, Aoki J, Nakamura K, Ichikawa A, Negishi M: Opposite regulation of transepithelial electrical resistance and paracellular permeability by Rho in Madin-Darby canine kidney cells. J Biol Chem 274:20982-20988, 1999
23. Saladik DT, Peralta Soler A, Lewis SA, Mullin JM: Cell division does not increase transepithelial permeability of LLC-PK1 cell sheets. Exp Cell Res 220:446-455, 1995
24. Simons RM, Laughlin KV, Kampherstein JA, Desai DC, Shurina RD, Mullin JM: Pentobarbital affects transepithelial electrophysiological parameters regulated by protein kinase C in rat distal colon. Dig Dis Sci 43:632-640, 1998
25. Thurman JD, Bucci TJ, Hart RW, Tuturro A: Survival, body weight, and spontaneous neoplasms in ad libitum-fed and food-restricted Fischer-344 rats. Toxicol Pathol 22:1-9, 1994
26. Sandle GI, McGlone F: Segmental variability of membrane conductances in rat and human colonic epithelia. Implications for Na, K and Cl transport. Pfleugers Arch 410:173-180, 1987
27. Takayama T, Katsuki S, Takahashi Y, Ohi M, Nojiri S, Sakamaki S, Kato J, Kogawa K, Miyake H, Niitsu Y: Aberrant crypt foci of the colon as precursors of adenoma and cancer. N Engl J Med 339:1277-1284, 1998
28. Shpitz B, Bomstein Y, Mekori Y, Cohen R, Kaufman Z, Neufeld D, Galkin M, Bernheim J: Aberrant crypt foci in human colons: distribution and histomorphologic characteristics. Hum Pathol 29:469-475, 1998
29. Tanakamaru Z, Mori I, Nishikawa A, Furukawa F, Takahashi M, Mori H: Essential similarities between spontaneous and MeIQx-promoted aberrant crypt foci in the F344 rat colon. Cancer Lett 172:143-149, 2001
30. Yang H, Glickman BW, de Boer JG: Effect of conjugated linoleic acid on the formation of spontaneous and PhIP-induced mutation in the colon and cecum of rats. Mutat Res 500:157-168, 2002
31. Takahashi M, Minamoto T, Yamashita N, Kato T, Yazawa K, Esumi H: Effect of docosahexaenoic acid on azozymethane-induced colon carcinogenesis in rats. Cancer Lett. 83:177-184, 1994
32. Magnuson BA, South EH, Exon JH, Dashwood RH, Xu M, Hendrix K, Hubele S: Increased susceptibility of adult rats to azoxymethane-induced aberrant crypt foci. Cancer Lett 161:185-193, 2000
33. Morotomi M, Sakaitani Y, Satou M, Takahashi T, Takagi A, Onoue M: Effects of a high-fat diet on azoxymethane-induced aberrant crypt foci and fecal biochemistry and microbial activity in rats. Nutr Cancer 27:84-91, 1997
34. Xiao Z, Moragoda L, Jaszewski R, Hatfield JA, Fligiel SE, Majumdar AP: Aging is associated with increased proliferation and decreased apoptosis in the colonic mucosa. Mech Aging Dev 122:1849-1864, 2001
35. Lee WC, Chao WT, Yang VC: Effects of high-cholesterol diet on the interendothelial clefts and the associated junctional complexes in rat aorta. Atherosclerosis 155:307-312, 2001
36. Davidson LA, Lupton JR, Jiang Y-H, Chang WC, Aukema HM, Chapkin RS: Dietary fat and fiber alter rat colonic protein kinase C isozyme expression. J Nutr 125:49-56, 1995
37. Mullin JM, Kampherstein JA, Laughlin KV, Clarkin CEK, Miller RD, Szallasi Z, Kachar B, Soler AP, Rosson D: Overexpression of protein kinase C-delta increases tight junction permeability in LLC-PK1 epithelia. Am J Physiol Cell Physiol 275:C544-C554, 1998
38. Rosson D, O'Brien TG, Kampherstein JA, Szallasi Z, Bogi K, Blumberg PM, and Mullin JM: Protein kinase C-alpha activity modulates transepithelial permeability and cell junctions in the LLC-PK1 epithelial cell line. J Biol Chem 272:14950-14953, 1997
39. Swisshelm K, Machl A, Planitzer S, Robertson R, Kubbies M, Hosier S: SEMP1, a senescence-associated cDNA isolated from human mammary epithelial cells, is a member of an epithelial membrane protein superfamily. Gene 226:285-295, 1999