An artificial peptide with corticotropin-releasing factor receptor-2 (CRF-R2) selective properties: The role of primary structure in the induction of signal transduction pathways

Journal of Peptide Research

Volumn 60, Issue 4, 2002, Pages 215-222

  Tellam, D J ^a   Lovejoy, D A ^a,c,c   Smart, D ^b   Qian, X ^c  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Anxiety; Corticotropin releasing factor; Receptor; Sauvagine; Signal transduction; Stress

Indexed keywords

ADENYLATE CYCLASE; AMINO ACID; CALCIUM; CORTICOTROPIN RELEASING FACTOR RECEPTOR; CORTICOTROPIN RELEASING FACTOR RECEPTOR 2; CYCLIC AMP; DNA; GUANYLATE CYCLASE; MITOGEN ACTIVATED PROTEIN KINASE; PEPTIDE HORMONE; SAUVAGINE; UNCLASSIFIED DRUG; UROCORTIN; CORTICOTROPIN RELEASING FACTOR; CRF RECEPTOR TYPE 2; PEPTIDE;

ACIDIFICATION; AMINO ACID SEQUENCE; ANIMAL TISSUE; ANXIETY; ARTICLE; BASE PAIRING; CHO CELL; DNA SCREENING; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN MOTIF; RAT; RECEPTOR AFFINITY; SECOND MESSENGER; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; SOLID; STRESS; STRUCTURE ANALYSIS; ANIMAL; CHEMISTRY; ENZYME SPECIFICITY; GENE LIBRARY; GENETICS; HAMSTER; HUMAN; LONG EVANS RAT; METABOLISM; MOLECULAR GENETICS; MOUSE; PROTEIN BINDING; SEQUENCE ALIGNMENT;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

AMINO ACID SEQUENCE; ANIMALS; CHO CELLS; CORTICOTROPIN-RELEASING HORMONE; CRICETINAE; GENOMIC LIBRARY; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PEPTIDES; POLYMERASE CHAIN REACTION; PROTEIN BINDING; RATS; RATS, LONG-EVANS; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY;

EID: 0036794241     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3011.2002.21024.x     Document Type: Article

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