Genotype B hepatitis B virus is associated with severe icteric flare-up of chronic hepatitis B virus infection in Hong Kong

American Journal of Gastroenterology

Volumn 97, Issue 10, 2002, Pages 2629-2633

  Lik Yuen Chan, Henry ^a,c   Woon Choi Tsang, Steven ^b   Wong, May Ling ^a   Tse, Chi Hang ^a   Wai Yee Leung, Nancy ^a   Ka Leung Chan, Francis ^a   Jao Yiu Sung, Joseph ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b TSEUNG KWAN O HOSPITAL   (Hong Kong)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; BILIRUBIN;

ADULT; ARTICLE; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE CARRIER; FEMALE; GENOTYPE; HEPATITIS B; HEPATITIS B VIRUS; HONG KONG; HUMAN; LIVER CIRRHOSIS; MALE; PREVALENCE; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; VIRUS STRAIN;

ADULT; DNA, VIRAL; FEMALE; GENOTYPE; HEPATITIS B E ANTIGENS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HONG KONG; HUMANS; JAUNDICE; LIVER CIRRHOSIS; MALE; MIDDLE AGED;

EID: 0036792742     PISSN: 00029270     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9270(02)04423-4     Document Type: Article

References (30)

1. Viola LA, Coleman JC, Fluker JL, et al. Natural history of liver disease in chronic hepatitis B surface antigen carriers. Survey of 100 patients from Great Britain. Lancet 1981;ii:1156-9.
2. Lok ASF, Lai CL. A longitudinal follow-up of asymptomatic hepatitis B surface antigen-positive Chinese patients. Hepatology 1988;8:1130-3.
3. Davis GL, Hoofnagle JH, Waggoner JG. Spontaneous reactivation of chronic hepatitis B virus infection. Gastroenterology 1984;86:230-5.
4. Sheen IS, Liaw YF, Tai DI, et al. Hepatic decompensation associated with hepatitis B e antigen clearance in chronic type B hepatitis. Gastroenterology 1985;89:732-5.
5. Fattovich G, Rugge M, Brollo L, et al. Clinical, virological and histologic outcome following seroconversion from HBeAg to anti-HBe in chronic hepatitis type B. Hepatology 1986;6:167-72.
6. Bortolotti F, Cadrobbi P, Crivellaro C, et al. Long-term outcome of chronic type B hepatitis in patients who acquire hepatitis B virus infection in childhood. Gastroenterology 1990;99:805-10.
7. Hoofnagle JH, Dusheiko GM, Seeff LB, et al. Seroconversion from hepatitis B e antigen to antibody in chronic type B hepatitis. Ann Intern Med 1981;94:744-8.
8. Fattovich G, Brollo L, Giustina G, et al. Natural history and prognostic factors of chronic hepatitis type B. Gut 1991;32:294-8.
9. Liaw YF, Tai DI, Chu CM, et al. The development of cirrhosis in patients with chronic type B hepatitis: A prospective study. Hepatology 1988;8:493-6.
10. Liaw YF, Lin DY, Chen TJ, et al. Natural course after the development of cirrhosis in patients with chronic type B hepatitis: A prospective study. Liver 1989;235-40.
11. Liaw YF, Tai DI, Chu CM, et al. Acute exacerbation in chronic type B hepatitis: Comparison between HBeAg and antibody-positive patients. Hepatology 1987;7:20-3.
12. Lok ASF, Lai CL. Acute exacerbation in Chinese patients with chronic hepatitis B virus (HBV) infection. J Hepatol 1990;10:29-34.
13. Chien RN, Lin CH, Liaw YF. Benefit of lamivudine therapy in hepatic decompensation during acute exacerbation of chronic hepatitis B. J Gastroenterol Hepatol 2000;15(suppl):F19.
14. Norder H, Courouce AM, Magnius LO. Complete genomes, phylogenetic relatedness, and structural proteins of six strains of the hepatitis B virus, four of which represent two new genotypes. Virology 1994;198:489-503.
15. Stuyver L, De Gendt S, Van Geyt C, et al. A new genotype of hepatitis B virus: Complete genome and phyllogenetic relatedness. J Gen Virol 2000;81:67-74.
16. Lindh M, Anderson AS, Gusdal A. Genotypes, nt 1858 variants, and geographical origin of hepatitis B virus-large scaled analysis using a new genotyping method. J Infect Dis 1997;175:1285-93.
17. Kao JH, Chan PJ, Lai MY, et al. Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B. Gastroenterology 2000;118:554-9.
18. Chan HLY, Leung NWY, Hussain M, et al. Hepatitis B e antigen-negative chronic hepatitis B in Hong Kong. Hepatology 2000;31:763-8.
19. Sung JJY, Chan HLY, Wong ML, et al. Which is best predictor of hepatitis activity in HBeAg-negative patients: Alanine transaminase (ALT), HBV DNA, pre-core/core promoter mutation or viral genotypes? Gastroenterology 2001;120(suppl 1):A554-5 (abstract).
20. Chan HLY, Tsang SWC, Leung NWY, et al. Occult hepatitis B virus (HBV) infection in cryptogenic liver cirrhosis in an area with high prevalence of HBV infection. Am J Gastroenterol 2002;97:1211-5.
21. Lai VCH, Guan R, Wook ML, et al. Nucleic acid-based cross-linking assay for detection and quantification of hepatitis B virus DNA. J Clin Microbiol 1999;37:161-4.
22. Chan HLY, Leung NWY, Lau TCM, et al. Comparison of three different sensitive assays for hepatitis B virus DNA in monitoring of responses to anti-viral therapy. J Clin Microbiol 2000;38:3205-8.
23. Chan HLY, Hussain M, Lok ASF. Different hepatitis B virus genotypes are associated with different mutations in the core promoter and precore regions during HBeAg seroconversion. Hepatology 1999;29:976-84.
24. Tsai SL, Chan PJ, Lai MY, et al. Acute exacerbation of chronic type B hepatitis are accompanied by increased T cell responses to hepatitis B core and e antigens? Implications for hepatitis e antigen seroconversion. J Clin Invest 1992;89:87-96.
25. Lok ASF. Natural history and control of perinatally acquired hepatitis B virus infection. Dig Dis 1992;10:46-52.
26. Chisari FV, Ferrari C. Hepatitis B virus immunopathogenesis. Annu Rev Immunol 1995;13:29-60.
27. Orito E, Mizokami M, Sakugawa H, et al. A case-control study for clinical and molecular biological differences between hepatitis B virus of genotype B and C. Hepatology 2001;33:218-33.
28. Lindh M, Hannoun C, Dhillon AP, et al. Core promoter mutations and relation to viral replication and liver damage in East Asian hepatitis B virus carriers. J Infect Dis 1999;179:775-82.
29. Mayerat C, Mantegani A, Frei PC. Does hepatitis B virus (HBV) genotype influence the clinical outcome of HBV infection. J Viral Hepat 1999;6:299-304.
30. Teo EK, Ostapowicz G, Hussain M, et al. Hepatitis B infection in patients with acute liver failure in the United States. Hepatology 2001;33:972-6.