Altered regional brain glucose metabolism in Duchenne muscular dystrophy: A PET study

Muscle and Nerve

Volumn 26, Issue 4, 2002, Pages 506-512

  Lee, Joon Soo ^a   Pfund, Zoltán ^a   Juhász, Csaba ^a   Behen, Michael E ^a   Muzik, Otto ^a   Chugani, Diane C ^a   Nigro, Michael A ^a   Chugani, Harry T ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Brain glucose metabolism; Duchenne muscular dystrophy; Neuropsychological assessment; Positron emission tomography; Statistical parametric mapping

Indexed keywords

DYSTROPHIN; GLUCOSE;

ADULT; ARTICLE; BRAIN METABOLISM; CEREBELLUM; CLINICAL ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DUCHENNE MUSCULAR DYSTROPHY; GLUCOSE METABOLISM; HIPPOCAMPUS; HUMAN; INTELLECTUAL IMPAIRMENT; MALE; NEUROPSYCHOLOGY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHOOL CHILD; STATISTICAL ANALYSIS; TEMPORAL CORTEX;

ADOLESCENT; ADULT; BRAIN; BRAIN CHEMISTRY; BRAIN MAPPING; CHILD; CHILD, PRESCHOOL; COGNITION; FEMALE; FLUORODEOXYGLUCOSE F18; GLUCOSE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MUSCULAR DYSTROPHY, DUCHENNE; NEUROPSYCHOLOGICAL TESTS; PSYCHOMOTOR PERFORMANCE; RADIOPHARMACEUTICALS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0036788690     PISSN: 0148639X     EISSN: None     Source Type: Journal    
DOI: 10.1002/mus.10238     Document Type: Article

References (43)

1. Al-Qudah AA, Kobayashi J, Chuang S, Dennis M, Ray P. Etiology of intellectual impairment in Duchenne muscular dystrophy. Pediatr Neurol 1990;6:57-59.
2. Bergström M, Litton J, Eriksson L, Bohm C, Blomqvist G. Determination of object contour from projections for attenuation correction in cranial positron emission tomography. J Comput Assist Tomogr 1982;6365-6372.
3. Bresolin N, Castelli E, Comi GP, Felisari G, Bardoni A, Perani D, Grassi F, Turconi A, Mazzucchelli F, Gallotti D, Moggio M, Prelle A, Ausenda C, Fazio G, Scarlato G. Cognitive impairment in Duchenne muscular dystrophy. Neuromuscul Disord 1994;4:359-369.
4. Chamberlain JS, Pearlman JA, Muzny DM, Gibbs RA, Ranier JE, Caskey CT, Reeves AA. Expression of the murine Duchenne muscular dystrophy gene in muscle and brain. Science 1988;239:1416-1418.
5. Chugani HT, Behen ME, Muzik O, Juhász C, Nagy F, Chugani DC. Local brain functional activity following early deprivation: a study of post-institutionalized Romanian orphans. Neuroimage 2001;14:1290-301.
6. 18FDG positron emission tomography. Science 1986;231:840-843.
7. Chugani HT, Phelps ME, Mazziotta JC. Positron emission tomography study of human brain functional development. Ann Neurol 1987;22:487-497.
8. Darian-Smith I, Galea MP, Darian-Smith C. Manual dexterity: how does the cerebral cortex contribute? Clin Exp Pharmacol Physiol 1996;23:948-956.
9. Devinsky O, Bear D. Varieties of aggressive behavior in temporal lobe epilepsy. Am J Psychiatry 1984;141:651-656.
10. +)-ATPase content is elevated in mdx mice: implications for the regulation of ions in dystrophic muscle. J Neurol Sci 1995;133:11-15.
11. Dunn JF, Zaim-Wadghiri Y. Quantitative magnetic resonance imaging of the mdx mouse model of Duchenne muscular dystrophy. Muscle Nerve 1999;22:1367-1371.
12. Eichenbaum H. A cortical-hippocampal system for declarative memory. Nat Rev Neurosci 2000;1:41-50.
13. Felisari G, Martinelli Boneschi F, Bardoni A, Sironi M, Comi GP, Robotti M, Turconi AC, Lai M, Corrao G, Bresolin N. Loss of Dp140 dystrophin isoform and intellectual impairment in Duchenne dystrophy. Neurology 2000;55:559-564.
14. Fiez JA, Petersen SE, Cheney MK, Raichle ME. Impaired non-motor learning and error detection associated with cerebellar damage. A single case study. Brain 1992;115:155-178.
15. Friston KJ, Ashburner J, Poline JB, Frith CD, Heather JD, Frackowiak RSJ. Spatial registration and normalization of images. Hum Brain Mapping 1995;2:165-189.
16. Friston KJ, Holmes AP, Worsley KJ, Poline JB, Frith CD, Frackowiak RSJ. Statistical parametric maps in functional imaging: a general approach. Hum Brain Mapping 1995;2:189-210.
17. Haws CM, Lansman JB. Calcium-permeable ion channels in cerebellar neurons from mdx mice. Proc R Soc Lond B Biol Sci 1991;244:185-189.
18. Hinton VJ, De Vivo DC, Nereo NE, Goldstein E, Stern Y. Poor verbal working memory across intellectual level in boys with Duchenne dystrophy. Neurology 2000;54:2127-2132.
19. Hoffman EP, Brown RHJr, Kunkel LM. Dystrophin: the protein product of the Duchenne muscular dystrophy locus. Cell 1987;51:919-928.
20. Hopf FW, Steinhardt RA. Regulation of intracellular free calcium in normal and dystrophic mouse cerebellar neurons. Brain Res 1992;578:49-54.
21. Huard J, Tremblay JP. Localization of dystrophin in the Purkinje cells of normal mice. Neurosci Lett 1992;137:105-108.
22. Jagadha V, Becker LE. Brain morphology in Duchenne muscular dystrophy: a Golgi study. Pediatr Neurol 1988;4:87-92.
23. Jain AK. Fundamentals of digital image processing. London: Prentice-Hall; 1998. 592 p.
24. Juhász C, Behen ME, Muzik O, Chugani DC, Chugani HT. Bilateral prefrontal and temporal neocortical hypometabolism in children with epilepsy and aggression. Epilepsia 2001;42:991-1001.
25. Karagan NJ. Intellectual functioning in Duchenne muscular dystrophy: a review. Psychol Bull 1979;86:250-259.
26. Lidov HG, Byers TJ, Kunkel LM. The distribution of dystrophin in the murine central nervous system: an immunocytochemical study. Neuroscience 1993;54:167-187.
27. Lidov HG, Byers TJ, Watkins SC, Kunkel LM. Localization of dystrophin to postsynaptic regions of central nervous system cortical neurons. Nature 1990;725-728.
28. Liu Y, Rouiller EM. Mechanisms of recovery of dexterity following unilateral lesion of the sensorimotor cortex in adult monkeys. Exp Brain Res 1999;128:149-159.
29. Mehler MF. Brain dystrophin, neurogenetics and mental retardation. Brain Res Brain Res Rev 2000;32:277-307.
30. Moizard MP, Toutain A, Fournier D, Berret F, Raynoud M, Billard C, Andres C, Moraine C. Severe cognitive impairment in DMD: obvious clinical indication for Dp71 isoform point mutation. Eur J Hum Genet 2000;552-556.
31. Moser H. Duchenne muscular dystrophy: pathogenetic aspects and genetic prevention. Hum Genet 1984;66:17-40.
32. Muzik O, Chugani DC, Juhász C, Shen C, Chugani HT. Statistical parametric mapping: assessment of application in children. Neuroimage 2000;12:538-549.
33. Rae C, Griffin JL, Blair DH, Bothwell JH, Bubb WA, Maitland A, Head S. Abnormalities in brain biochemistry associated with lack of dystrophin: studies of the mdx mouse. Neuromuscul Disord 2002;12:121-129.
34. Rae C, Scott B, Thompson CH, Dixon RM, Dumughn I, Kemp GJ, Male A, Pike M, Styles P, Radda GK. Brain biochemistry in Duchenne muscular dystrophy: a 1H magnetic resonance and neuropsychological study. J Neurol Sci 1998;160:148-157.
35. Sattler JM. Assessment of children, 3rd edition. San Diego: Sattler Publisher; 1992. p 96-137.
36. Sbriccoli A, Santarelli M, Carretta D, Pinto F, Granato A, Minciacchi D. Architectural changes of the cortico-spinal system in the dystrophin defective mdx mouse. Neurosci Lett 1995;200:53-56.
37. Schmahmann JD. An emerging concept. The cerebellar contribution to higher function. Arch Neurol 1991;48:1178-1187.
38. Shaywitz BA, Shaywitz SE, Pugh KR, Constable RT, Skudlarski P, Fulbright RK, Bronen RA, Fletcher JM, Shankweiler DP, Katz L, Gore JC, Herbert Y. Sex differences in the functional organization of the brain for language. Nature 1995;373:607-609.
39. Talairach J, Tournoux P. Co-planar stereotaxic atlas of the human brain. Stuttgart: Thieme; 1988. 12 p.
40. Tracey I, Dunn JF, Parkes HG, Radda GK. An in vivo and vitro 1H-magnetic resonance spectroscopy study of mdx mouse brain: abnormal development or neural necrosis? J Neurol Sci 1996;141:13-18.
41. Tracey I, Scott RB Thompson CH, Dunn JF, Barnes PR, Styles P, Kemp GJ, Rae CD, Pike M, Radda GK. Brain abnormalities in Duchenne muscular dystrophy: phosphorus-31 magnetic resonance spectroscopy and neuropsychological study. Lancet 1995;345:1260-1264.
42. Yoshioka M, Okuno T, Honda Y, Nakano Y. Central nervous system involvement in progressive muscular dystrophy. Arch Dis Child 1980;55:589-594.
43. Zubrzycka-Gaarn EE, Bulman DE, Karpati G, Burghes AH, Belfall B, Klamut HJ, Talbot J, Hodges RS, Ray PN, Worton RG. The Duchenne muscular dystrophy gene product is localized in sarcolemma of human skeletal muscle. Nature 1988;333;466-469.