Quantitative magnetic resonance imaging of the mdx mouse model of duchenne muscular dystrophy

Muscle and Nerve

Volumn 22, Issue 10, 1999, Pages 1367-1371

  Dunn, Jeff F ^a   Zaim Wadghiri, Youssef ^a  

^a DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

Author keywords

Dystrophy; Magnetic resonance imaging; Mdx; T1; T2; Water content

Indexed keywords

ANIMAL MODEL; ARTICLE; BRAIN; CONTROLLED STUDY; DISEASE COURSE; DUCHENNE MUSCULAR DYSTROPHY; EXPERIMENTAL MODEL; GASTROCNEMIUS MUSCLE; MOUSE; MUSCLE CONTRACTION; MUSCULAR DYSTROPHY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SOLEUS MUSCLE;

ANIMALS; BRAIN; HINDLIMB; MAGNETIC RESONANCE IMAGING; MICE; MICE, INBRED C57BL; MICE, INBRED MDX; MUSCLE, SKELETAL; MUSCULAR DYSTROPHY, ANIMAL; MUSCULAR DYSTROPHY, DUCHENNE; REFERENCE VALUES;

EID: 0032880643     PISSN: 0148639X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4598(199910)22:10<1367::AID-MUS5>3.0.CO;2-H     Document Type: Article

References (26)

1. Carnwath JW, Shotton DM. Muscular dystrophy in the mdx mouse: histopathology of the soleus and extensor digitorum longus muscles. J Neurol Sci 1987;80:39-54.
2. Clemens PR, Kochanek S, Sunada Y, Chan S, Chen HH, Campbell KP, Caskey CT. In vivo muscle gene transfer of full-length dystrophin with an adenoviral vector that lacks all viral genes. Gene Ther 1996;3:965-972.
3. Coulton GR, Morgan JE, Partridge TA, Sloper JC. The mdx mouse skeletal muscle myopathy: I. A histochemical, morphometric and biochemical investigation. Neuropathol Appl Neurobiol 1988;14:53-70.
4. Cremillieux Y, Ding S, Dunn J. High resolution in vivo measurements of transverse relaxation times in rats at 7 Tesla. Magn Reson Med 1997;39:285-290.
5. Dangain J, Vrbova G. Muscle development in mdx mutant mice. Muscle Nerve 1984;7:700-704.
6. Dunn JF, Bannister N, Kemp GJ, Publicover SJ. Sodium is elevated in mdx muscles: ionic interactions in dystrophic cells. J Neurol Sci 1993;114:76-80.
7. Ervasti JM, Campbell KP. Membrane organization of the dystrophin-glycoprotein complex. Cell 1991;66:1121-1131.
8. Feero WG, Li S, Rosenblatt JD, Sirianni N, Morgan JE, Partridge TA, Huang L, Hoffman EP. Selection and use of ligands for receptor-mediated gene delivery to myogenic cells. Gene Ther 1997;4:664-674.
9. Hoffman EP, Brown RH, Kunkel LK. Dystrophin: the protein product of the muscular dystrophy locus. Cell 1987;51: 919-928.
10. Hoffman EP, Hudecki MS, Rosenberg PA, Pollina CM, Kunkel LM. Cell and fibre-type distribution of dystrophin. Neuron 1988;1:411-420.
11. Huang Y, Majumdar S, Genant HK, Chan WP, Sharma KR, Yu P, Mynhier M, Miller RG. Quantitative MR relaxometry study of muscle composition and function in Duchenne muscular dystrophy. J Magn Reson Imag 1994;4:59-64.
12. Karpati G, Ajdukovic D, Arnold D, Gledhill RB, Guttmann R, Holland P, Koch PA, Shoubridge E, Spence D, Vanasse M, Watters GV, Abarhamowicz M, Duff C, Worton RG. Myoblast transfer in Duchenne muscular dystrophy. Ann Neurol 1993; 34:8-17.
13. Koenig S. The molecular basis of magnetic relaxation of water protons in tissue. Acad Radiol 1996;3:597-606.
14. Koenig SH. Cholesterol of myelin is the determinant of gray-white contrast in MRI of brain. Magn Reson Med 1991;20: 285-291.
15. Levitt MH, Freeman R. Compensation for pulse imperfections in NMR spin-echo experiments. J Magn Reson 1981;43: 65-80.
16. Matsumura K, Nakano I, Fukuda N, Ikehira H, Tateno Y, Aoki Y. Proton spin-lattice relaxation time of Duchenne dystrophy skeletal muscle by magnetic resonance imaging. Muscle Nerve 1988;11:97-102.
17. 1 differentiation between normal and dystophic muscle. Magn Reson Imag 1984;2:33-35.
18. Narayana PA, Brey WW, Kulkarni MV, Misra LK. In vivo proton spin-lattice relaxation times of normal and dystophic muscles. Magn Reson Med 1987;4:153-161.
19. Partridge TA, Morgan JE, Coulton GR, Hoffman EP, Kunkel LM. Conversion of mdx myofibres from dystrophin-negative to -positive by injection of normal myoblasts. Nature 1989; 337:176-179.
20. Phoenix J, Betal D, Roberts N, Helliwell T, Edwards R. Objective quantification of muscle and fat in human dystrophic muscle by magnetic resonance image analysis. Muscle Nerve 1996;19:302-310.
21. 2 quantitation for clinical applications. J Magn Reson Imag 1992;2:541-553.
22. Rothwell NC, Stock MJ. Modification of body composition by clenbuterol in normal and dystrophic (mdx) mice. Biosci Rep 1985;5:755-760.
23. Sicinski P, Geng Y, Ryder-Cook AS, Barnard EA, Darlison MG, Barnard PJ. The molecular basis of muscular dystrophy in the mdx mouse: a point mutation. Science 1989;244:1578-1580.
24. Tanabe Y, Esaki K, Nomura T. Skeletal muscle pathology in ×chromosome-linked muscular dystrophy (mdx) mouse. Acta Neuropathol 1986;69:91-95.
25. Tracey I, Dunn JF, Radda GK. Brain metabolism is abnormal in the mdx model of Duchenne muscular dystrophy. Brain 1996;119:1039-1044.
26. Tracey I, Scott RB, Thompson CH, Dunn JF, Barnes PR, Styles P, Kemp GJ, Rae CD, Pike M, Radda GK. Brain abnormalities in Duchenne muscular dystrophy: phosphorus-31 magnetic resonance spectroscopy and neuropsychological study. Lancet 1995;345:1260-1264.