The effects of lidocaine and adrenergic agonists on rat sciatic nerve and skeletal muscle blood flow in vivo

Anesthesia and Analgesia

Volumn 95, Issue 4, 2002, Pages 1080-1086

  Palmer, Greta M ^a   Cairns, Brian E ^a   Berkes, Steven L ^a   Dunning, Patricia S ^a   Taylor, George A ^a   Berde, Charles B ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; ADRENERGIC RECEPTOR STIMULATING AGENT; LIDOCAINE; PHENYLEPHRINE;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD FLOW; BLOOD VESSEL TONE; CONTROLLED STUDY; DRUG CLEARANCE; ISOTOPE LABELING; LINEAR REGRESSION ANALYSIS; MALE; MASSETER MUSCLE; MUSCLE BLOOD FLOW; NERVE BLOCK; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; RAT; SCIATIC NERVE; TISSUE BLOOD FLOW; VASOCONSTRICTION;

EID: 0036784837     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/00000539-200210000-00054     Document Type: Article

References (20)

1. Liu S, Carpenter RL, Chiu AA, et al. Epinephrine prolongs duration of subcutaneous infiltration of local anesthesia in a dose-related manner. Reg Anesth 1995;20:378-84.
2. Sinnott CJ, Garfield JM, Thalhammer JG, Stichartz GR. Addition of sodium bicarbonate to lidocaine decreases the duration of peripheral nerve block in the rat. Anesthesiology 2000;93: 1045-52.
3. Myers RR, Heckman HM. Effects of local anesthesia on nerve blood flow: studies using lidocaine with and without epinephrine. Anesthesiology 1989;71:757-62.
4. Partridge BL. The effects of local anesthetics and epinephrine on rat sciatic nerve blood flow. Anesthesiology 1991;75:243-51.
5. Evans GRD, Gheradini G, Gurlek A, et al. Drug-induced vasodilation in an in vitro and in vivo study: the effects of nicardipine, papaverine and lidocaine on the rabbit carotid artery. Plast Reconstr Surg 1997;100:1475-81.
6. Bernards CM, Kopacz DJ. Effect of epinephrine on lidocaine clearance in vivo: a microdialysis study in humans. Anesthesiology 1999;91:962-8.
7. Warner MA, Kunkel SE, Offord KO, et al. The effects of age, epinephrine and operative site on duration of caudal analgesia in pediatric patients. Anesth Analg 1987;66:995-8.
8. Mazoit JX, Benhamou D, Veillette Y, Samii K. Clonidine and or adrenaline decrease lignocaine plasma peak concentration after epidural injection. Br J Clin Pharmacol 1996;42:242-5.
9. Aps C, Reynolds F. The effect of concentration on vasoactivity of bupivacaine and lignocaine. Br J Anaesth 1976;48:1171-4.
10. Johns RA, Difazio CA, Longnecker DE. Lidocaine constricts or dilates rat arterioles in a dose dependent manner. Anesthesiology 1985;62:141-4.
11. Popitz-Berger FA, Leeson S, Strichartz GR, Thalhammer JG. Relation of functional deficit and intraneural local anesthetic during peripheral nerve block. Anesthesiology 1995;83:583-92.
12. Thalhammer JG, Vladimirova M, Bershadadsky B, Strichartz GR. Neurologic evaluation of the rat during sciatic nerve blockade with lidocaine. Anesthesiology 1995;82:1013-25.
13. Popitz-Berger FA, Leeson S, Thalhammer JG, Strichartz GR. Intraneural lidocaine uptake compared with analgesic differences between pregnant and non-pregnant rats. Reg Anesth 1997;22:363-71.
14. Goetz TE, Manohar M, Nganwa D, Gustafson R. A study of the effect of isoflurane anesthesia on equine skeletal muscle perfusion. Equine Vet J Suppl 1989;7:133-7.
15. Prinzen FW, Bassingthwaighte JB. Blood flow distributions by microsphere deposition methods. Cardiovasc Res 2000;45:13-21.
16. Soul JS, Taylor GA, Wypij D, et al. Noninvasive detection of changes in cerebral blood flow by near-infrared spectroscopy in a piglet model of hydrocephalus. Pediatr Res 2000;48:445-9.
17. Lescanic ML, Miller ED, Difazio CA. The effects of lidocaine on the whole body distribution of radioactively labeled microspheres in the conscious rat. Anesthesiology 1981;55:269-72.
18. Stehling L. Autologous transfusion. In: Miller RD, ed. Anesthesia. 5th ed. Philadelphia: Churchill Livingstone, 2000:1651.
19. Berde CB, Cairns BE. Glutamate-induced sensitization of masseter muscle afferents is associated with a shortened duration of local anesthesia [abstract]. J Pain 2001;2S;34.
20. Sugimoto H, Monafo WM, Eliasson S. Regional sciatic nerve and muscle blood flow in conscious and anesthetized rats. Am J Physiol 1986;251:H1211-6.