Detection of the presence of catalytic subunit mRNA associated with telomerase gene in exfoliated urothelial cells from patients with bladder cancer

Journal of Urology

Volumn 168, Issue 4 I, 2002, Pages 1574-1577

  Isurugi, Kazumasa ^a   Suzuki, Yasushi ^a   Tanji, Susumu ^a   Fujioka, Tomoaki ^a  

^a IWATE MEDICAL UNIVERSITY   (Japan)

Author keywords

Bladder; Bladder neoplasms; Gene expression; Telomerase; Urothelium

Indexed keywords

CELL PROTEIN; MESSENGER RNA; TELOMERASE; TELOMERASE ASSOCIATED PROTEIN 1; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ARTICLE; BLADDER CARCINOMA; BLADDER IRRIGATION; CANCER CELL CULTURE; CANCER DIAGNOSIS; CANCER GRADING; CANCER SCREENING; CELL COUNT; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; ENZYME ACTIVE SITE; FEMALE; FOLLOW UP; GENE EXPRESSION; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RNA ANALYSIS; URINALYSIS; URINARY TRACT DISEASE; UROTHELIUM;

EID: 0036784266     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0022-5347(05)64523-5     Document Type: Article

References (14)

1. Activation of telomerase in a human tumor
2. The RNA component of human telomerase
3. Functional characterization and developmental regulation of mouse telomerase RNA
4. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization
5. Expression of the catalytic subunit associated with telomerase gene in human urinary bladder cancer
6. Specific association of human telomerase activity with immortal cells and cancer
7. Detection of telomerase activity in exfoliated cells in urine from patients with bladder cancer
8. Evaluation of the telomeric repeat amplification protocol (TRAP) assay for telomerase as a diagnostic modality in recurrent bladder cancer
9. Comparison of human telomerase RNA and telomerase activity in urine for diagnosis of bladder cancer
10. Telomerase in human bladder cancer
11. Expression of human telomerase subunits and correlation with telomerase activity in urothelial cancer
12. Detection of human telomerase reverse transcriptase messenger RNA in voided urine samples as a useful diagnostic tool for bladder cancer