Revisiting an old antimicrobial drug: Amphotericin B induces interleukin-1-converting enzyme as the main factor for inducible nitric-oxide synthase expression in activated endothelia

Molecular Pharmacology

Volumn 62, Issue 4, 2002, Pages 936-946

  Suschek, Christoph Viktor ^a   Bonmann, Eckhard ^b   Kapsokefalou, Anna ^a   Hemmrich, Karsten ^a   Kleinert, Hartmut ^c   Förstermann, Ulrich ^c   Kröncke, Klaus Dietrich ^a   Mahotka, Csaba ^a   Kolb Bachofen, Victoria ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; AMPHOTERICIN B DEOXYCHOLATE; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ANTIFUNGAL ACTIVITY; ARTERY ENDOTHELIUM; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; DRUG POTENCY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; GENE ACTIVITY; HUMAN; IMMUNOMODULATION; NEPHROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RAT;

AMPHOTERICIN B; ANIMALS; ANTIBIOTICS, ANTIFUNGAL; CASPASE 1; CYTOKINES; ENDOTHELIUM, VASCULAR; ENZYME INDUCTION; GENE EXPRESSION; HUMANS; INTERLEUKIN-1; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PROMOTER REGIONS (GENETICS); RATS; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036783740     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.62.4.936     Document Type: Article

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