Amphotericin B severely affects expression and activity of the endothelial constitutive nitric oxide synthase involving altered mRNA stability

British Journal of Pharmacology

Volumn 131, Issue 3, 2000, Pages 473-481

  Suschek, Christoph Viktor ^a   Bonmann, Eckhard ^b   Kleinert, Hartmut ^c   Wenzel, Michael ^d   Mahotka, Csaba ^d   Kolb, Hubert ^e   Förstermann, Ulrich ^c   Gerharz, Claus Dieter ^d   Kolb Bachofen, Victoria ^a  

^a UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

^d HEINRICH HEINE UNIVERSITY   (Germany)

^e LEIBNIZ CENTER FOR DIABETES RESEARCH AT HEINRICH HEINE UNIVERSITY DÜSSELDORF   (Germany)

Author keywords

Amphotericin B; ecNOS; Endothelial cells; Nitric oxide

Indexed keywords

AMPHOTERICIN B; AMPHOTERICIN B DEOXYCHOLATE; MESSENGER RNA; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ANIMAL TISSUE; ANTIFUNGAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG PROTEIN BINDING; ENDOTHELIUM CELL; ENZYME ACTIVITY; GLOMERULUS CAPILLARY; HUMAN; HUMAN CELL; KIDNEY FAILURE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; RAT; VASOCONSTRICTION;

EID: 0033780867     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703576     Document Type: Article

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