Endomorphin-2 modulates productions of TNF-α, IL-1β, IL-10, and IL-12, and alters functions related to innate immune of macrophages

Inflammation

Volumn 26, Issue 5, 2002, Pages 223-232

  Azuma, Yasutaka ^a   Ohura, Kiyoshi ^a  

^a OSAKA DENTAL UNIVERSITY   (Japan)

Author keywords

Endomorphin 2; Innate immunity; Macrophages; Proinflammatory cytokines

Indexed keywords

CD11B ANTIGEN; ENDOMORPHIN 2; FIBRONECTIN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 1BETA; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; INTERLEUKIN 1; NARCOTIC ANALGESIC AGENT; OLIGOPEPTIDE;

ANIMAL CELL; ARTICLE; CHEMOTAXIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; ESCHERICHIA COLI; FLOW CYTOMETRY; IMMUNITY; INFLAMMATION; LEUKOCYTE ADHERENCE; MACROPHAGE; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OPSONIZATION; PHAGOCYTOSIS; PROTEIN EXPRESSION; RAT; TH1 CELL; TH2 CELL; ANIMAL; BIOSYNTHESIS; CELL ADHESION; CELLULAR IMMUNITY; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; IMMUNOLOGY; METABOLISM; PERITONEUM MACROPHAGE; WISTAR RAT;

ANIMALIA; ESCHERICHIA COLI;

ANALGESICS, OPIOID; ANIMALS; CELL ADHESION; CHEMOTAXIS; CYTOKINES; FIBRONECTINS; IMMUNITY, CELLULAR; INTERLEUKIN-1; INTERLEUKIN-10; INTERLEUKIN-12; MACROPHAGE-1 ANTIGEN; MACROPHAGES, PERITONEAL; MALE; OLIGOPEPTIDES; PHAGOCYTOSIS; RATS; RATS, WISTAR; SUPEROXIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036779774     PISSN: 03603997     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1019766602138     Document Type: Article

References (51)

1. Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the muμ-opioid-receptor gene
2. A potent and selective endogenous agonist for the mu-opiate receptor
3. Opioids and pain
4. Expression of prepro-enkephalin in human articular chondrocytes is linked to cell proliferation
5. The control of pain in peripheral tissue by opioids
6. Comparison of the effect of lidocaine-epinephrine and prilocaine-felypressine to alter macrophage functions
7. 2 inhibits IL-10 and IL-12 production by macrophages
8. 2-receptors
9. Comparative studies of modulatory effect to the function of rat peritoneal neutrophils treated with new quinolones
10. Differentiation by in vitro treatment of lidocaine-epinephrine and prilocaine-felypressine in neutrophils
11. Quinolones alter defense reactions mediated by macrophages
12. A rapid and simple microfluorometric phagocytosis assay
13. Comparison of inhibitory effects of local anesthetics on immune functions of neutrophils
14. Endomorphins 1 and 2 modulate chemotaxis, phagocytosis and superoxide anion production by microglia
15. 2 is a negative regulator of macrophage functions
16. Possible interaction between new quinolones and immune functions in macrophages
17. Rapid microassays for the measurement of superoxide and hydrogen peroxide production by macrophages in culture using an automatic enzyme immunoassay reader
18. Immunomodulation of the neutrophil respiratory burst by endomorphins 1 and 2
19. Interleukin-12: A cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes
20. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes
21. Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes
22. Diffrential regulation of TNFα, IL-1β, IL-6, IL-8, TNFβ and IL-10 by pentoxifylline
23. Modulation of interleukin-1β production by cyclic AMP in human monocytes
24. Cellular and molecular regulation of TNF-alpha production by pentoxifylline
25. Cyclic nucleotides differentially regulate the synthesis of tumor necrosis factor-α and interleukin-1β by human mononuclear cells
26. Differential effects of pentoxifylline on the production of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) by monocytes and T cells
27. Lead treatment in vitro at early developmental stage of bone marrow-derived macrophages enhances NO production through IL-1β and IL-6 but not TNFα
28. Application of transcriptional and posttranscriptional receptor constructs to the analysis of tumor necrosis factor gene regulation
29. Constitutive activity of the tumor necrosis factor promoter is canceled by the 3′ untranslated region in non macrophage cell lines; a trans-dominant factor overcomes this suppressive effect
30. Morphine suppresses complement receptor expression, phagocytosis, and respiratory burst in neutrophils by a nitric oxide and μ3 opiate receptor-dependent mechanism
31. Suppression of peritoneal macrophage phagocytosis of Candida albicans by opioids
32. Enhancement of phagocytosis by dynorphin A in mouse peritoneal macrophages
33. Effect of morphine on Fc-mediated phagocytosis by murine macrophages in vitro
34. Reversibility of morphine effects on phagocytosis by murine macrophages
35. Enhanced chemotaxis of monocytes in rheumatoid arthritis
36. Atherosclerosis-an inflammatory disease
37. β-endorphin and metenkephalin stimulate human peripheral blood mononuclear cell chemotaxis
38. Opiate-like substances in an invertebrate, an opiate receptor on invertebrate and human immunocytes, and a role in immunosuppression
39. Opioids suppress chemokine-mediated migration of monkey neutrophils and monocytes-an instant response
40. Neutral proteinases of human mononuclear phagocytes. Cellular differentiation markedly alters cell phenotype for serine proteinases, metalloproteinases, and tissue inhibitor of metalloproteinases
41. Matrix metalloproteinase-9 (92 kDa gelatinase/type IV collagenase) from U937 monoblastoid cells: Correlation with cellular invasion
42. Neutral metallo-proteinases produced by human mononuclear phagocytes. Enzyme profile, regulation, and expression during cellular development
43. Morphine modulates 72-kDa matrix metalloproteinase
44. Polarization of chemoattractant receptor signaling during neutrophil chemotaxis
45. Opioid peptides rapidly stimulate superoxide production by human polymorphonuclear leukocytes and macrophages
46. Opioid-mediated suppression of cultured peripheral blood mononuclear cell respiratory burst activity
47. Suppression of human peripheral blood mononuclear cell function by methadone and morphine
48. Influence of beta-endorphin on the production of reactive oxygen and nitrogen intermediates by rabbit alveolar macrophages
49. Role of protein kinases in stimulation of human polymorphonuclear leukocyte oxidative metabolism by various agonists
50. Protein kinase C and the activation of the human neutrophil NADPH-oxidase
51. Protein kinase C activity is not involved in N-formylmethionyl-leucylphenylalanine-induced phospholipase D activation in human neutrophils, but is essential for concomitant NADPH oxidase activation: Studies with a staurosporine analogue with improved selectivity for protein kinase C