A single mutation in the carboxy terminus of reovirus outer-capsid protein σ3 confers enhanced kinetics of σ3 proteolysis, resistance to inhibitors of viral disassembly, and alterations in σ3 structure

Journal of Virology

Volumn 76, Issue 19, 2002, Pages 9832-9843

  Wilson, Gregory J ^a   Nason, Emma L ^a   Hardy, Charles S ^a   Ebert, Daniel H ^a   Wetzel, J Denise ^a   Venkataram Prasad, B V ^a   Dermody, Terence S ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIUM CHLORIDE; CAPSID PROTEIN; CATHEPSIN D; CATHEPSIN L; PROTEIN SIGMA3; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CHEMICAL REACTION KINETICS; ENDOSOME; GENE MUTATION; INSECT CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STRUCTURE; REOVIRUS; SEQUENCE ANALYSIS; VIRUS ASSEMBLY; VIRUS TRANSMISSION;

CAPSID; CAPSID PROTEINS; ENDOCYTOSIS; ENDOPEPTIDASES; KINETICS; POINT MUTATION; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; RNA-BINDING PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; VIRION; VIRUS ASSEMBLY;

EID: 0036776316     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.76.19.9832-9843.2002     Document Type: Article

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