Pathophysiology of gestational diabetes;Physiopathologie du diabète gestationnel

Journal de Gynecologie Obstetrique et Biologie de la Reproduction

Volumn 31, Issue 6 SUPPL., 2002, Pages

  Vambergue, A ^a   Valat, A S ^a   Dufour, P ^a   Cazaubiel, M ^a   Fontaine, P ^a   Puech, F ^a  

^a LILLE UNIVERSITY HOSPITAL   (France)

Author keywords

Gestational diabetes; Insulin resistance; Insulin secretion

Indexed keywords

CARBOHYDRATE METABOLISM; CONFERENCE PAPER; FEMALE; GLUCOSE TOLERANCE; HUMAN; INSULIN RELEASE; INSULIN SENSITIVITY; NON INSULIN DEPENDENT DIABETES MELLITUS; PATHOPHYSIOLOGY; PREGNANCY DIABETES MELLITUS;

DIABETES, GESTATIONAL; FEMALE; HUMANS; INSULIN; INSULIN RESISTANCE; LEPTIN; PREGNANCY;

EID: 0036776147     PISSN: 03682315     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (56)

1. Jimenez-Moleon JJ, Bueno-Cavanillas A, Luna-del-Castillo JD, Garcia-Martin M, Lardelli-Claret P, Galvez-Vargas R. Prevalence of gestational diabetes mellitus: Variations related to screening strategy used. Eur J Endocrinol 2002; 146: 831-7.
2. Boden G. Fuel metabolism in pregnancy and in gestational diabetes mellitus. Obstet Gynecol Clin North Am 1996; 23: 1-10.
3. Kuhl C. Insulin secretion and insulin resistance in pregnancy and GDM: Implications for diagnosis and management. Diabetes 1991; 40: 18-24.
4. Catalano PM, Tyzbir ED, Roman NM, Amini SM, Sims EAH. Longitudinal changes in insulin release and insulin resistance in nonobese pregnant women. Am J Obstet Gynecol 1991; 165: 1667-72.
5. Kautzky-Willer A, Thomaseth K, Ludvik B, Nowotny P, Rabensteiner D, Waldhausl W, et al. Elevated islet amyloid pancreatic polypeptide and proinsulin in lean gestational diabetes. Diabetes 1997; 46: 607-14.
6. Zimmer DM, Golichowski AM, Karn CA, Brechtel G, Baron AD, Denne SC. Glucose and amino acid turnover in untreated gestational diabetes. Diabetes Care 1996; 19: 591-6.
7. Hornnes PJ, Kuhl C, Lauritsen KB. Gastrointestinal insulinotropic hormones in normal and gestational diabetic pregnancy response to oral glucose. Diabetes 1981; 30: 504-9.
8. Catalano PM, Tyzbir ED, Wolfe RR, Roman NM, Amini SB, Sims EAH. Longitudinal changes in basal hepatic glucose production and suppression during insulin infusion in normal pregnant women. Am J Obstet Gynecol 1992; 167: 913-9.
9. Kuhl C, Hoist JJ. Plasma glucagon and the insulin: Glucagon ratio in gestational diabetes. Diabetes 1976; 25: 16-23.
10. Bowes SB, Hennessy TR, Umpleby AM, Benn JJ, Jackson NC, Boroujerdy MA, et al. Measurement of glucose metabolism and insulin secretion during normal pregnancy and pregnancy complicated by gestational diabetes. Diabetologia 1996; 39: 976-83.
11. Buchanan TA, Metzger BE, Freinkel N, Bergman RN. Insulin sensitivity and B-cell responsiveness to glucose during late pregnancy in lean and moderately obese women with normal glucose tolerance or mild gestational diabetes. Am J Obstet Gynecol 1990; 162: 1008-14.
12. Kautzky-Willer A, Prager R, Waldhausl W, Pacini G, Thomaseth K, Wagner OF, et al. Pronounced insulin resistance and inadequate B-cell secretion in lean gestational diabetes mellitus during and after pregnancy. Diabetes Care 1997; 20: 1717-23.
13. Hornnes PJ, Kuhl C, Lauritsen KB. Gastro-entero-pancreatic hormones in gestational diabetes: Response to a protein rich meal. Horm Metab Res 1982; 14: 335-8.
14. Hornnes PJ, Kuhl C, Krarup T. Gastroenteropancreatic hormones in normal and gestational diabetic pregnancy: Response to oral lipid. Metabolism 1984; 33: 304-8.
15. Kuhl C. Serum proinsulin in normal and gestational diabetic pregnancy. Diabetologia 1976; 12: 295-300.
16. Dornhorst A, Davies M, Amyaoku V, Hampton SM, Elkeles RS, Beard RW, et al. Abnormalities of fasting circulating proinsulin concentrations in mild gestational diabetes. Clin Endocrinol 1991; 34: 211-3.
17. Swinn RA, Wareham NJ, Gregory R, Curling V, Clark PM, Dalton KJ, et al. Excessive secretion of insulin precursors characterizes and predicts gestational diabetes. Diabetes 1995; 44: 911-5.
18. Nicholls JS, Ali K, Gray IP, Andres C, Niththyananthan R, Beard RW, et al. Increased maternal fasting proinsulin as a predictor of insulin requirement in women with gestational diabetes. Diabetes 1994; 11: 57-61.
19. Piva I, Erie G, Thiella M, Lora L, Strazzabosco M, Sicolo N, et al. A study on the hyperinsulinism of late pregnancy. J Endocrinol Invest 1991; 14: 807-14.
20. Sheridan JP, Anaya PA, Parsons JA, Sorenson RL. Increased dye coupling in pancreatic islets from rats in late term pregnancy. Diabetes 1988; 37: 908-11.
21. Stoffel ML, Bell K, BlackBurn CL, Powell KL, Seo TS, Takeda J, et al. Identification of glucokinase mutations in subjects with gestational diabetes mellitus. Diabetes 1993; 42: 937-40.
22. Chiu KC, Go RCP, Aoki M, Riggs AC, Tanizawa Y, Acton RT, et al. Glucokinase gene in gestational diabetes mellitus: Population study and molecular scanning. Diabetologia 1994; 37: 104-10.
23. Yen SS. Endocrine regulation of metabolic homeostasis during pregnancy. Clin Obstet Gynecol 1973; 16: 130-47.
24. Ryan EA, O'Sullivan MJ, Skyler JS. Insulin action during pregnancy with the euglycemic clamp technique. Diabetes 1985; 34: 380-9.
25. Catalano MP, Tyzbir ED, Wolfe RR, Calles J, Roman NM, Amini SB, et al. Carbohydrate metabolism during pregnancy in control subjects and women with gestational diabetes. Am J Physiol 1993; 264: 60-7.
26. Cousins L. Insulin sensitivity in pregnancy. Diabetes 1991; 40: 39-43.
27. Beck-Nielsen H, Kuhl C, Pedersen O, Bjerre-Christensen C, Nielsen TT, et al. Decreased insulin binding to monocytes from normal pregnant women. J Clin Endocrinol Metab 1979; 49: 810-4.
28. Andersen O, Kuhl C. Insulin receptor binding to monocytes and erythrocytes during normal human pregnancy. Eur J Clin Invest 1986; 16: 226-32.
29. Andersen O, Kuhl C. Insulin receptor binding to monocytes and erythrocytes in gestational diabetes. Diabetes Metab 1987; 13: 607-12.
30. Andersen O, Kuhl C. Adipocyte insulin receptor binding and lipogenesis at term in normal pregnancy. Eur J Clin Invest 1988; 18: 575-81.
31. Hjohund E, Pedersen O, Espersen T. Impaired insulin receptor binding and post binding defect of adipocyte from normal and diabetic pregnant women. Diabetes 1986; 35: 598-03.
32. Mouzon SH, Peraldi P, Alengrin F, Obberghen EV. Alteration of phosphotyrosine phosphatase activity in tissues from diabetic and pregnant rats. Endocrinology 1992; 132: 67-74.
33. Friedman JE, Ishizuka T, Sao J, Huston L, Highman T, Catalano P. Impaired glucose transport and insulin receptor tyrosine phosphorylation in obese women with gestational diabetes mellitus. Diabetes 1999; 48: 1807-14.
34. Sbraccia P, Goodman PA, Maddux BA, Wong KY, Chen YD, Reaven GM, et al. Production of an inhibitor of insulin receptor tyrosine kinase in fibroblasts from a patient with insulin resistance and NIDDM. Diabetes 1991; 40: 295-9.
35. Shao J, Catalano PM, Yamashita H, Ruyter I, Smith S, Youngren J, et al. Decreased insulin receptor tyrosine kinase activity and plasma cell membrane glycoprotein-1 overexpression in skeletal muscle from obese women with gestational diabetes mellitus: Evidence for increased serine/threonine phosphorylation in pregnancy and GDM. Diabetes 2000; 49: 603-10.
36. Saad MJ, Maeda L, Brenelli SL, Carvalho CR, Paiva RS, Velloso LA. Defects in insulin signal transduction in liver and muscle of pregnants rats. Diabetologia 1997; 40: 179-86.
37. Yamashita H, Sao JH, Friedman JE. Physiologic and molecular alterations in carbohydrate metabolism during pregnancy and gestational diabetes mellitus. Clin Obstet Gynecol 2000; 43: 87-98.
38. Garvey WT, Maianu L, Zhu JH, Hancock JA, Golichowski AM. Multiple defects in the adipocyte glucose transport system cause cellular insulin resistance in gestational diabetes. Diabetes 1993; 42:1773-85.
39. Anderson O, Falholt K, Kuhl C. Activity of enzymes of glucose and triglycerides metabolism in adipose and muscle tissue from normal pregnant women at term. Diabet Med 1989; 6: 131-6.
40. Kirwan JP, Hauguel-de Mouzon S, Lepercq J, Challier JC, Huston-Presley L, Friedman JE, et al. TNF-alpha is a predictor of insulin resistance in human pregnancy. Diabetes 2002; 51: 2207-13.
41. Davidson MB. Insulin resistance of late pregnancy does not include the liver. Metabolism 1984; 33: 532-7.
42. Hauguel S, Gilbert M, Girard J. Pregnancy induced insulin resistance in liver and skeletal muscles of the conscious rabbit. Am J Physiol 1987; 252: 165-9.
43. Costrini NV, Kalkhoff RK. Relative effect of pregnancy estradiol and progesterone on plasma insulin and pancreatic islet insulin secretion. J Clin Invest 1971; 50: 992-9.
44. Ryan EA, Enns L. Role of gestational hormone in the induction of insulin resistance. J Clin Endocrinol Metab 1988; 67: 341-7.
45. Kalkhoff RK, Jacobson M, Lemper D. Progesterone, pregnancy, and the augmented plasma insulin response. J Clin Endocrinol 1970; 31: 24-8.
46. Nelson T, Schulman G, Grainger D, Diamond MP. Progesterone administration induced impairment of insulin suppression of hepatic glucose production. Fertil Steril 1994; 62: 491-6.
47. Skouby SO, Kuhl C, Honnes PJ, Andersen AN. Prolactin and glucose tolerance in normal and gestational diabetic pregnancy. Obstet Gynecol 1986; 67: 17-20.
48. Michaels RL, Sorenson RL, Parsons JA, Sheridan JD. Prolactin enhances cell-to-cell communication among beta-cells in pancreatic islets. Diabetes 1987; 36: 1098-103.
49. Rizza RA, Mandarino LJ, Gerich JE. Cortisol-induced insulin resistance in man: Impaired suppression of glucose production and stimulation of glucose utilization due to a postrecepteur defect of insulin action. Clin Endocrinol Metab 1982; 54: 131-8.
50. Giorgino F, Almahfouz A, Goodyear LJ, Smith RJ. Glucocorticoid regulation of insulin receptor IRS-1 tyrosine phosphorylation in rat skeletal muscle in vivo. J Clin Invest 1993; 91: 2020-30.
51. Masuzaki H, Ogawa U, Sagawa N, Hosoda K, Matsumoto T, Mise H, et al. Nonadipose tissue production of leptin: Leptin as a novel-derived hormone in humans. Nat Med 1997; 3: 1029-33.
52. Highman TJ, Friedman JE, Huston LP, Wong WW, Catalano PM. Longitudinal change in maternal serum leptin concentration, body composition and resting metabolic rate in pregnancy. Am J Obstet Gynecol 1998; 178: 1010-15.
53. Sivan E, Whittaker P, Sinha D, Homko CJ, Lin M, Reece EA, et al. Leptin in human pregnancy: The relationship with gestational hormones. Am J Obstet Gynecol 1998; 179: 1128-32.
54. Festa A, Shnawa N, Krugluger W, Hopmeier P, Schernthaner G, Haffner S. Relative hypoleptinaemia in women with mild gestational diabetes mellitus. Diabet Med 1999; 16: 656-62.
55. Kautzky-Willer A, Pacini G, Tura A, Biegimayer C, Schneider B, Ludvik B, et al. Increased plasma leptin in gestational diabetes. Diabetologia 2001; 44: 164-72.
56. Lepercq J, Cauzac M, Lahlou N, Timsit J, Girard Jauwer XJ, et al. Overexpression of placental leptin in diabetic pregnancy: A critical role for insulin. Diabetes 1998; 47: 847-50.