Clues to understanding the role of estrogen receptors in mediating cardiovascular protection

Cardiovascular Research

Volumn 56, Issue 1, 2002, Pages 4-7

  Du, Xiao Jun ^a  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; ANGIOTENSIN RECEPTOR; ATRIAL NATRIURETIC FACTOR; BLOOD CLOTTING FACTOR; CALCIUM CHANNEL; CELL ADHESION MOLECULE; CYCLIC AMP; CYTOKINE; DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIN 1; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; GUANYLATE CYCLASE; METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE SYNTHASE; POTASSIUM CHANNEL; PROSTAGLANDIN SYNTHASE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; TISSUE PLASMINOGEN ACTIVATOR; VASCULOTROPIN;

APOPTOSIS; ATHEROSCLEROSIS; BLOOD VESSEL INJURY; CARDIOVASCULAR RISK; CARDIOVASCULAR SYSTEM; CELL DIFFERENTIATION; EDITORIAL; ENDOTHELIUM CELL; ENDOTHELIUM LESION; ESTROGEN RESPONSIVE ELEMENT; FIBROBLAST; GENE EXPRESSION REGULATION; GENE TARGETING; GENETIC TRANSCRIPTION; GROWTH REGULATION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; HORMONE ACTION; HUMAN; LIPID METABOLISM; MENOPAUSE; MORBIDITY; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR BINDING; SEX DIFFERENCE; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER;

ADULT; CARDIOVASCULAR DISEASES; ESTROGENS; FEMALE; HOMEOSTASIS; HUMANS; MALE; MIDDLE AGED; MYOCARDIUM; NEUTROPHILS; NITRIC OXIDE; RECEPTORS, ESTROGEN;

EID: 0036774266     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(02)00573-4     Document Type: Editorial

References (35)

1. Mendelsohn M.E., Karas R.H. The protective effects of estrogen on the cardiovascular system. New Engl J Med. 340:1999;1801-1811.
2. Dubey R.K., Jackson E.K. Estrogen-induced cardiorenal protection: potential cellular, biochemical, and molecular mechanisms. Am J Physiol. 280:2001;F365-F388.
3. Babiker F.A., De Windt L.J., van Eickels M., et al. Estrogenic hormone action in the heart: regulatory network and function. Cardiovasc Res. 53:2002;709-719.
4. Hall J.M., Couse J.F., Korach K.S. The multifaceted mechanisms of estradiol and estrogen receptor signaling. J Biol Chem. 276:2001;36869-36872.
5. Rosenfeld M.G., Glass C.K. Coregulator codes of transcriptional regulation by nuclear receptors. J Biol Chem. 276:2001;36865-36868.
6. Saville B., Wormke M., Wang F., et al. Ligand-, cell-, and estrogen receptor subtype (α/β)-dependent activation at GC-rich (Sp1) promoter elements. J Biol Chem. 275:2000;5379-5387.
7. Stefano G.B., Prevot V., Beauvillain J.C., et al. Cell-surface estrogen receptors mediate calcium-dependent nitric oxide release in human endothelia. Circulation. 101:2000;1594-1597.
8. + channels in human coronary artery smooth muscle cells. Cardiovasc Res. 53:2002;650-661.
9. Nakajima T., Iwasawa K., Oonuma H., et al. Antiarrhythmic effect and its underlying ionic mechanism of 17β-estradiol in cardiac myocytes. Br J Pharmacol. 127:1999;429-440.
10. Schwartz C.J., Kelley J.L., Nerem R.M., et al. Pathophysiology of the atherogenic process. Am J Cardiol. 64:1989;23G-30G.
11. Hansen P.R. Role of neutrophils in myocardial ischemia and reperfusion. Circulation. 91:1995;1872-1885.
12. Albertine K.H., Weyrich A.S., Ma X.L., et al. Quantification of neutrophil migration following myocardial ischemia and reperfusion in cats and dogs. J Leukoc Biol. 55:1994;557-566.
13. Delyani J.A., Murohara T., Nossuli T.O., Lefer A.M. Protection from myocardial reperfusion injury by acute administration of 17β-estradiol. J Mol Cell Cardiol. 28:1996;1001-1008.
14. Molero L., Garcia-Duran M., Diaz-Recasens J., et al. Expression of estrogen receptor subtypes and neuronal nitric oxide synthase in neutrophils from women and men. Regulation by estrogen. Cardiovasc Res. 56:2002;43-51.
15. Stefano G.B., Cadet P., Breton C., et al. Estradiol-stimulated nitric oxide release in human granulocytes is dependent on intracellular calcium transients: evidence of a cell surface estrogen receptor. Blood. 95:2000;3951-3958.
16. Garcia-Duran M., de Frutos T., Diaz-Recasens J., et al. Estrogen stimulates neuronal nitric oxide synthase protein expression in human neutrophils. Circ Res. 85:1999;1020-1026.
17. Kubes P., Suzuki M., Granger D.N. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci USA. 88:1991;4651-4655.
18. Pace P., Taylor J., Suntharalingam S., Coombes R.C., Ali S. Human estrogen receptor β binds DNA in a manner similar to and dimerizes with estrogen receptor α J Biol Chem. 272:1997;25832-25838.
19. Zhu Y., Bian Z., Lu P., et al. Abnormal vascular function and hypertension in mice deficient in estrogen receptor β Science. 295:2002;505-508.
20. Pare G., Krust A., Karas R.H., et al. Estrogen receptor-α mediates the protective effects of estrogen against vascular injury. Circ Res. 90:2002;1087-1092.
21. Nuedling S., Karas R.H., Mendelsohn M.E., et al. Activation of estrogen receptor β is a prerequisite for estrogen-dependent upregulation of nitric oxide synthases in neonatal rat cardiac myocytes. FEBS Lett. 502:2001;103-108.
22. Maruyama S., Fujimoto N., Asano K., Ito A. Suppression by estrogen receptor β of AP-1 mediated transactivation through estrogen receptor α J Steroid Biochem Mol Biol. 78:2001;177-184.
23. Liu M.M., Albanese C., Anderson C.M., et al. Opposing action of estrogen receptors α and β on cyclin D1 gene expression. J Biol Chem. 277:2002;24353-24360.
24. Lindner V., Kim S.K., Karas R.H., et al. Increased expression of estrogen receptor-β mRNA in male blood vessels after vascular injury. Circ Res. 83:1998;224-229.
25. Savolainen H., Frosen J., Petrov L., Aavik E., Hayry P. Expression of estrogen receptor sub-types α and β in acute and chronic cardiac allograft vasculopathy. J Heart Lung Transplant. 20:2001;1252-1264.
26. Jankowski M., Rachelska G., Donghao W., McCann S.M., Gutkowska J. Estrogen receptors activate atrial natriuretic peptide in the rat heart. Proc Natl Acad Sci USA. 98:2001;11765-11770.
27. Griffin M., Lee H.W., Zhao L., Eghbali-Webb M. Gender-related differences in proliferative response of cardiac fibroblasts to hypoxia: effects of estrogen. Mol Cell Biochem. 215:2000;21-30.
28. Stefano G.B., Peter D. Cell surface estrogen receptors coupled to cNOS mediate immune and vascular tissue regulation: therapeutic implications. Med Sci Monit. 7:2001;1066-1074.
29. Shaul P.W. Regulation of endothelial nitric oxide synthase: location, location, location. Annu Rev Physiol. 64:2002;749-774.
30. Kim H.P., Lee J.Y., Jeong J.K., et al. Nongenomic stimulation of nitric oxide release by estrogen is mediated by estrogen receptor α localized in caveolae. Biochem Biophys Res Commun. 263:1999;257-262.
31. Chen Z., Yuhanna I.S., Galcheva-Gargova Z., et al. Estrogen receptor α mediates the nongenomic activation of endothelial nitric oxide synthase by estrogen. J Clin Invest. 103:1999;401-406.
32. 2+ influx on rat heart by 17β-estradiol. Cell Signal. 12:2000;47-52.
33. Razandi M., Pedram A., Greene G.L., Levin E.R. Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: studies of ERα and ERβ expressed in Chinese hamster ovary cells. Mol Endocrinol. 13:1999;307-319.
34. Vasudevan N., Kow L.M., Pfaff D.W. Early membrane estrogenic effects required for full expression of slower genomic actions in a nerve cell line. Proc Natl Acad Sci USA. 98:2001;12267-12271.
35. Chen D., Pace P.E., Coombes R.C., Ali S. Phosphorylation of human estrogen receptor α by protein kinase A regulates dimerization. Mol Cell Biol. 19:1999;1002-1015.