The prevalence of TT virus and GB virus C/hepatitis G virus infection in individuals with raised liver enzymes but without HBV or HCV infection in Taiwan

Epidemiology and Infection

Volumn 129, Issue 2, 2002, Pages 307-313

  Dai, C Y ^a   Yu, M L ^a   Chang, W Y ^a   Tseng, C H ^b   Hou, C ^a   Lin, Z Y ^a   Chen, S C ^a   Hsieh, M Y ^a   Wang, L Y ^a   Tsai, J F ^a   Chuang, W L ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; HEPATITIS B SURFACE ANTIGEN; HEPATITIS C ANTIBODY; LIVER ENZYME; PROTEIN ANTIBODY; VIRUS DNA; VIRUS ENVELOPE PROTEIN; VIRUS RNA;

ADULT; AGE DISTRIBUTION; AGED; ANALYSIS OF VARIANCE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME BLOOD LEVEL; FEMALE; GENDER; GENOTYPE; HEPATITIS B VIRUS; HEPATITIS C; HEPATITIS C VIRUS; HEPATITIS G; HEPATITIS G VIRUS; HUMAN; LIVER FUNCTION TEST; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; PHYLOGENY; PREVALENCE; SEQUENCE ANALYSIS; TAIWAN; TORQUE TENO VIRUS; VIREMIA; VIRUS ISOLATION;

ADULT; AGED; ALANINE TRANSAMINASE; ANTIGENS, VIRAL; DNA VIRUS INFECTIONS; DNA, VIRAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLAVIVIRIDAE INFECTIONS; GB VIRUS C; HEPACIVIRUS; HEPATITIS B SURFACE ANTIGENS; HEPATITIS, CHRONIC; HEPATITIS, VIRAL, HUMAN; HUMANS; MALE; MIDDLE AGED; PREVALENCE; RETROSPECTIVE STUDIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, VIRAL; SEX FACTORS; TAIWAN; TORQUE TENO VIRUS; VIRAL ENVELOPE PROTEINS;

EID: 0036772840     PISSN: 09502688     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0950268802007264     Document Type: Article

References (39)

1. Simons JN, Leary TP, Dawson GJ, et al. Isolation of novel virus-like sequences associated with human hepatitis. Nat Med 1995; 1: 564-9.
2. Linnen J, Wages J Jr, Zhang-Keck ZY, et al. Molecular cloning and disease association of hepatitis G virus: a tranfusion-transmissible agent. Science 1996; 271: 505-8.
3. Yoshiba M, Okamoto H, Mishiro S. Detection of the GBV-C hepatitis virus genome in serum from patients with fulminant hepatitis of unknown etiology. Lancet 1995; 346: 1131-2.
4. Alter MJ, Gallagher M, Morris TT, et al. Acute non-A-E hepatitis in the United States and the role of hepatitis G virus infection. N Engl J Med 1997; 336: 741-6.
5. Alter HJ, Nakatsuji Y, Melpolder J, et al. The incidence of transfusion-associated hepatitis G virus infection and its relation to liver disease. N Engl J Med 1997; 336: 747-54.
6. Nishizawa T, Okamoto H, Konishi K, Yoshizawa H, Miyakawa Y, Mayumi M. A novel DNA virus (TTV) associated with elevated transaminase levels in posttransfusion hepatitis of unknown etiology. Biochem Biophys Res Commun 1997; 241: 92-7.
7. Okamoto H, Nishizawa T, Kato N, et al. Molecular cloning and characterization of a novel virus (TTV) associated with posttransfusion hepatitis of unknown etiology. Hepatol Res 1998; 10: 1-16.
8. Mushahwar IK, Erker JC, Muerhoff AS, et al. Molecular and biophysical characterization of TT virus: evidence for a new virus family infecting humans. Proc Natl Acad Sci USA 1999; 96: 3177-82.
9. Fujiwara T, Iwata A, Iizuka H, Tanaka T, Okamoto H. Transfusion transmitted virus. Lancet 1998; 352: 1310-1.
10. Okamoto H, Nishizawa T, Ukita M. A novel unenveloped DNA virus (TT virus) associated with acute and chronic non-A to G hepatitis. Intervirology 1999; 42: 196-204.
11. Tanaka H, Okamoto H, Luengrojanakul P, et al. Infection with an unenveloped DNA virus (TTV) associated with posttransfusion non-A to G hepatitis in hepatitis patients and healthy blood donors in Thailand. J Med Virol 1998; 56: 234-8.
12. Hohne M, Berg T, Muller AR, Schreier E. Detection of sequences of TT virus, a novel DNA virus, in German patients. J Gen Virol 1998; 79: 2761-4.
13. Lo SY, Peng KF, Ma HC, et al. Prevalence of TT virus DNA in eastern Taiwan aborigines. J Med Virol 1999; 59: 198-203.
14. Takayama S, Miura T, Matsuo S, Taki M, Sugii S. Prevalence and persistence of a novel DNA TT virus (TTV) infection in Japanese haemophiliacs. British J Haematol 1999; 104: 626-9.
15. Hsieh SY, Wu YH, Ho YP, Tsao KC, Yeh CT, Liaw YF. High prevalence of TT virus infection in healthy children and adults and in patients with liver disease in Taiwan. J Clin Microbiol 1999; 37: 1829-31.
16. Kao JH, Chen W, Hsiang SC, Chen PJ, Lai MY, Chen DS. Prevalence and implication of TT virus infection: minimal role in patients with non-A-E hepatitis in Taiwan. J Med Virol 1999; 59: 307-12.
17. Tanaka M, Nishiguchi S, Tanaka T, et al. Prevalence of TT virus in patients with fulminant hepatic failure in Japan. J Gastroenterol 1999; 34: 589-93.
18. Nakano T, Park YM, Mizokami M, et al. TT virus infection among blood donors and patients with non-B, non-C liver diseases in Korea. J Hepatol 1999; 30: 389-93.
19. Gimenez-Barcons M, Forns X, Ampurdanes S, et al. Infection with a novel human DNA virus (TTV) has no pathogenic significance in patients with liver diseases. J Hepatol 1999; 30: 1028-34.
20. Okamoto H, Takahashi M, Nishizawa T, et al. Marked genomic heterogeneity and frequent mixed infection of TT virus demonstrated by PCR with primers from coding and noncoding regions. Virology 1999; 259: 428-36.
21. Chuang WL, Chang WY, Lu SN, et al. The role of hepatitis C virus in chronic hepatitis B virus infection. Gastroenterol Jpn 1993; 28 (Suppl 5): 23-7.
22. Wang JH, Lu SN, Wu JC, et al. A hyperendemic community of hepatitis B virus and hepatitis C virus infection in Taiwan. Trans R Soc Trop Med Hyg 1999; 93: 1-2.
23. Yu ML, Chuang WL, Lu SN, et al. The genotypes of hepatitis C virus in patients with chronic hepatitis C virus infection in southern Taiwan. Kaohsiung J Med Sci 1996; 12: 605-12.
24. Mukaide M, Mizokami M, Orito E, et al. Three different GB virus C/hepatitis G virus genotypes. Phylogenetic analysis and a genotyping assay based on restriction fragment length polymorphism. FEBS Letters 1997; 407: 51-8.
25. Tacke M, Kiyosawa K, Stark K, et al. Detection of antibodies to a putative hepatitis G virus envelope protein. Lancet 1997; 349: 318-20.
26. Yu ML, Chuang WL, Wang LY, et al. Status and natural course of GB virus C/hepatitis G virus infection among high-risk groups and volunteer blood donors in Taiwan. J Gastroenterol Hepatol 2000; 15: 1404-10.
27. Yu ML, Chuang WL, Dai CY, et al. The serological and molecular epidemiology of GB virus C/hepatitis G virus infection in a hepatitis C and B endemic area. J Infect 2001; 42: 61-6.
28. Saback FL, Gomes SA, de Paula VS, da Silva RR, Lewis-Ximenez LL, Niel C. Age-specific prevalence and transmission of TT virus. J Med Virol 1999; 59: 318-22.
29. Dai CY, Yu ML, Chuang WL, et al. Epidemiology and clinical significance of hepatitis-related viruses infection in hemodialysis patients from Taiwan. Nephron 2002; 90: 148-53.
30. Yuki N, Kato M, Masuzawa M, et al. Clinical implications of coinfection with a novel DNA virus (TTV) in hepatitis C virus carriers on maintenance hemodialysis. J Med Virol 1999; 59: 431-6.
31. Oguchi T, Tanaka E, Orii K, Kobayashi M, Hora K, Kiyosawa K. Transmission of and liver injury by TT virus in patients on maintenance hemodialysis. Am J Gastroenterol 1999; 34: 234-40.
32. Okamoto H, Akahane Y, Ukita M, et al. Fecal excretion of a nonenveloped DNA virus (TTV) associated with posttransfusion non-A-G hepatitis. J Med Virol 1998; 56: 128-32.
33. Tuveri R, Jaffredo F, Lunel F, et al. Impact of TT virus infection in acute and chronic, viral- and non viral-related liver diseases. J Hepatol 2000; 33: 121-7.
34. Akahane Y, Sakamoto M, Miyazaki Y, et al. Effect of interferon on a nonenveloped DNA virus (TT virus) associated with acute and chronic hepatitis of unknown etiology. J Med Virol 1999; 58: 196-200.
35. Hagiwara H, Hayashi N, Mita E, et al. Influence of transfusion-transmitted virus infection on the clinical features and response to interferon therapy in Japanese patients with chronic hepatitis C. J Viral Hepat 1999; 6: 463-9.
36. Dai CY, Yu ML, Chuang WL, et al. The response of hepatitis C virus and TT virus to high dose and long duration interferon-alpha therapy in naïve chronic hepatitis C patients. Antivir Res 2002; 53: 9-18.
37. Bacon BR, Farahvash MJ, Janney CG, Neuschwander-Tetri BA. Nonalcoholic steatohepatitis: an expanded clinical entry. Gastroenterology 1994; 107: 1103-9.
38. Gallian P, Biagini P, Zhong S, et al. TT virus: a study of molecular epidemiology and transmission of genotypes 1, 2 and 3. J Clin Microbiol 2000; 17: 43-9.
39. Charlton M, Adjei P, Poterucha J, et al. TT-virus infection in North American blood donors, patients with fulminant hepatic failure, and cryptogenic cirrhosis. Hepatology 1998; 28: 839-42.