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Volumn 22, Issue 5, 2002, Pages 2863-2868

Inhibition of P-glycoprotein transport function by N-acylphenothiazines

Author keywords

Flow cytometry; Multidrug resistance; P glycoprotein; Phenothiazine derivatives

Indexed keywords

GLYCOPROTEIN P; PHENOTHIAZINE ACETYLAMIDE DERIVATIVE; PHENOTHIAZINE DERIVATIVE; PHENOTHIAZINE MALEATE DERIVATIVE; PHENOTHIAZINE METHOXYCARBONYLAMIDE DERIVATIVE; PHENOTHIAZINE METHYLSULFONYLAMIDE DERIVATIVE; RHODAMINE 123; UNCLASSIFIED DRUG;

EID: 0036765439     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (23)

References (31)
  • 1
    • 0030577119 scopus 로고    scopus 로고
    • P-glycoprotein multidrug resistance and cancer
    • Bosch I and Croop J: P-glycoprotein multidrug resistance and cancer. Biochim Biophys Acta 1288: F37-F54, 1996.
    • (1996) Biochim Biophys Acta , vol.1288
    • Bosch, I.1    Croop, J.2
  • 3
    • 0034329373 scopus 로고    scopus 로고
    • Antitumor potential and possible targets of phenothiazine-related compounds
    • Motohashi N, Kawase M, Saito S and Sakagami H: Antitumor potential and possible targets of phenothiazine-related compounds. Curr Drug Targets 1: 237-245, 2000.
    • (2000) Curr Drug Targets , vol.1 , pp. 237-245
    • Motohashi, N.1    Kawase, M.2    Saito, S.3    Sakagami, H.4
  • 4
    • 0020426820 scopus 로고
    • Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors
    • Tsuruo T, Iida H, Tsukagoshi S and Sakurai Y: Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors. Cancer Res 42: 4730-4733, 1982.
    • (1982) Cancer Res , vol.42 , pp. 4730-4733
    • Tsuruo, T.1    Iida, H.2    Tsukagoshi, S.3    Sakurai, Y.4
  • 5
    • 0022513314 scopus 로고
    • Factors governing the modulation of vinca-alkaloid resistance in doxorubicin-resistant cells by the calmodulin inhibitor trifluoperazine
    • Ganapathi R, Grabowski D and Schmidt H: Factors governing the modulation of vinca-alkaloid resistance in doxorubicin-resistant cells by the calmodulin inhibitor trifluoperazine. Biochem Pharmacol 35: 673-678, 1986.
    • (1986) Biochem Pharmacol , vol.35 , pp. 673-678
    • Ganapathi, R.1    Grabowski, D.2    Schmidt, H.3
  • 6
    • 0026624915 scopus 로고
    • Reversal of multidrug resistance by phenothiazines and structurally related compounds
    • Ramu A and Ramu N: Reversal of multidrug resistance by phenothiazines and structurally related compounds. Cancer Chemother Pharmacol 30: 165-173, 1992.
    • (1992) Cancer Chemother Pharmacol , vol.30 , pp. 165-173
    • Ramu, A.1    Ramu, N.2
  • 7
    • 0024534226 scopus 로고
    • Structural features determining activity of phenothiazines and related drugs for inhibition of cell growth and reversal of multidrug resistance
    • Ford JA, Prozialeck WC and Hait WN: Structural features determining activity of phenothiazines and related drugs for inhibition of cell growth and reversal of multidrug resistance. Mol Pharmacol 35: 105-115, 1989.
    • (1989) Mol Pharmacol , vol.35 , pp. 105-115
    • Ford, J.A.1    Prozialeck, W.C.2    Hait, W.N.3
  • 8
    • 0032554868 scopus 로고    scopus 로고
    • Molecular modelling of phenothiazines and related drugs as multidrug resistance modifiers: A comparative molecular field analysis study
    • Pajeva I and Wiese M: Molecular modelling of phenothiazines and related drugs as multidrug resistance modifiers: a comparative molecular field analysis study. J Med Chem 41: 1815-1826, 1998.
    • (1998) J Med Chem , vol.41 , pp. 1815-1826
    • Pajeva, I.1    Wiese, M.2
  • 9
    • 0029564436 scopus 로고
    • Effects of two benzo[a]phenothiazines on multi-drug resistance (mdr) and tumor antigen expression
    • Molnár J, Pusztai R, Hever A, Nagy S and Motohashi N: Effects of two benzo[a]phenothiazines on multi-drug resistance (mdr) and tumor antigen expression. Anticancer Res 15: 2013-2016, 1995.
    • (1995) Anticancer Res , vol.15 , pp. 2013-2016
    • Molnár, J.1    Pusztai, R.2    Hever, A.3    Nagy, S.4    Motohashi, N.5
  • 10
    • 0031057694 scopus 로고    scopus 로고
    • Inhibition of the transport function of membrane proteins by some substituted phenothiazines in E. coli and multidrug resistant tumor cells
    • Molnár J, Hever A, Fakla I, Fischer J, Ocsovski I and Aszalos A: Inhibition of the transport function of membrane proteins by some substituted phenothiazines in E. coli and multidrug resistant tumor cells. Anticancer Res 17: 481-486, 1997.
    • (1997) Anticancer Res , vol.17 , pp. 481-486
    • Molnár, J.1    Hever, A.2    Fakla, I.3    Fischer, J.4    Ocsovski, I.5    Aszalos, A.6
  • 14
    • 0013508682 scopus 로고
    • A retrovirus carrying an MDR-1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells
    • Pastan I, Gottesman MM, Ueda K, Lovelace E, Rutheford AV and Willingham MC: A retrovirus carrying an MDR-1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells. Proc Natl Sci USA 85: 4486-4490, 1988.
    • (1988) Proc Natl Sci USA , vol.85 , pp. 4486-4490
    • Pastan, I.1    Gottesman, M.M.2    Ueda, K.3    Lovelace, E.4    Rutheford, A.V.5    Willingham, M.C.6
  • 15
    • 0027195754 scopus 로고
    • The effect of ion channel blockers, immunosupressive agents, and other drugs on the activity of the multi-drug transporter
    • Weaver JL, Szabo G, Pine PS, Gottesman MM, Goldenberg S and Aszalos A: The effect of ion channel blockers, immunosupressive agents, and other drugs on the activity of the multi-drug transporter. Int J Cancer 54: 456-461, 1993.
    • (1993) Int J Cancer , vol.54 , pp. 456-461
    • Weaver, J.L.1    Szabo, G.2    Pine, P.S.3    Gottesman, M.M.4    Goldenberg, S.5    Aszalos, A.6
  • 16
    • 0023898749 scopus 로고
    • Physical-chemical properties shared by compounds that modulate multidrug resistance in human leukemic cells
    • Zamora JM, Pearce HL and Beck WT: Physical-chemical properties shared by compounds that modulate multidrug resistance in human leukemic cells. Mol Pharmacol 33: 454-462, 1988.
    • (1988) Mol Pharmacol , vol.33 , pp. 454-462
    • Zamora, J.M.1    Pearce, H.L.2    Beck, W.T.3
  • 17
    • 0017904125 scopus 로고
    • Calorimetric, 13C NMR, and 31P NMR studies on the interaction of some phenothiazine derivatives with dipalmitoyl phosphatidylcholine model membranes
    • Frenzel J, Arnold K and Nuhn P: Calorimetric, 13C NMR, and 31P NMR studies on the interaction of some phenothiazine derivatives with dipalmitoyl phosphatidylcholine model membranes. Biochim Biophys Acta 507: 185-197, 1978.
    • (1978) Biochim Biophys Acta , vol.507 , pp. 185-197
    • Frenzel, J.1    Arnold, K.2    Nuhn, P.3
  • 18
    • 0033963113 scopus 로고    scopus 로고
    • Chlorpromazine interaction with glycerophospholipid liposomes studied by magic angle spinning state 13C-NMR and differential scanning calorimetry
    • Nerdal W, Gundersen SA, Thorsen V, Hoiland H and Holmsen H: Chlorpromazine interaction with glycerophospholipid liposomes studied by magic angle spinning state 13C-NMR and differential scanning calorimetry. Biochim Biophys Acta 1464: 165-175, 2000.
    • (2000) Biochim Biophys Acta , vol.1464 , pp. 165-175
    • Nerdal, W.1    Gundersen, S.A.2    Thorsen, V.3    Hoiland, H.4    Holmsen, H.5
  • 19
    • 0035830598 scopus 로고    scopus 로고
    • Trifluoperazine induces domain formation in zwitterionic phosphatidylcholine but not in charged phosphatidylglycerol bilayers
    • Hendrich AB, Wesolowska O and Michalak K: Trifluoperazine induces domain formation in zwitterionic phosphatidylcholine but not in charged phosphatidylglycerol bilayers. Biochim Biophys Acta 1510: 414-425, 2001.
    • (2001) Biochim Biophys Acta , vol.1510 , pp. 414-425
    • Hendrich, A.B.1    Wesolowska, O.2    Michalak, K.3
  • 20
    • 0037922214 scopus 로고    scopus 로고
    • Chlorpromazine-induced increase in dipalmitoylphosphatidylserine surface area in monolayers at room temperature
    • Varnier Agasoster A, Tungodden LM, Cejka D, Bakstad E, Sydnes LK and Holmsen H: Chlorpromazine-induced increase in dipalmitoylphosphatidylserine surface area in monolayers at room temperature. Biochem Pharmacol 61: 817-825, 2001.
    • (2001) Biochem Pharmacol , vol.61 , pp. 817-825
    • Varnier Agasoster, A.1    Tungodden, L.M.2    Cejka, D.3    Bakstad, E.4    Sydnes, L.K.5    Holmsen, H.6
  • 21
    • 0035876680 scopus 로고    scopus 로고
    • Chlorpromazine associates with phosphatidylserines to cause an increase in lipid's own interfacial molecular area - Role of the fatty acid composition
    • Varnier Agasoster A Holmsen H: Chlorpromazine associates with phosphatidylserines to cause an increase in lipid's own interfacial molecular area - role of the fatty acid composition. Biophys Chem 91: 37-47, 2001.
    • (2001) Biophys Chem , vol.91 , pp. 37-47
    • Varnier Agasoster, A.1    Holmsen, H.2
  • 22
    • 0023277777 scopus 로고
    • Shape transformations induced by amphiphiles in erythrocytes
    • Isomaa B, Hagerstrand H and Paatero G: Shape transformations induced by amphiphiles in erythrocytes. Biochim Biophys Acta 899: 93-103, 1987.
    • (1987) Biochim Biophys Acta , vol.899 , pp. 93-103
    • Isomaa, B.1    Hagerstrand, H.2    Paatero, G.3
  • 23
    • 0024371548 scopus 로고
    • Vesiculation induced by amphiphiles in erythrocytes
    • Hagerstrand H and Isomaa B: Vesiculation induced by amphiphiles in erythrocytes. Biochim Biophys Acta 982: 179-186, 1989.
    • (1989) Biochim Biophys Acta , vol.982 , pp. 179-186
    • Hagerstrand, H.1    Isomaa, B.2
  • 24
    • 0029655680 scopus 로고    scopus 로고
    • Membrane interactions of some catamphiphilic drugs and relation to their multidrug-resistance-reversing ability
    • Pajeva IK, Wiese M, Cordes HP and Seydel JK: Membrane interactions of some catamphiphilic drugs and relation to their multidrug-resistance-reversing ability. J Cancer Res Clin Oncol 122: 27-40, 1996.
    • (1996) J Cancer Res Clin Oncol , vol.122 , pp. 27-40
    • Pajeva, I.K.1    Wiese, M.2    Cordes, H.P.3    Seydel, J.K.4
  • 25
    • 0027743492 scopus 로고
    • The role of drug-lipid interactions in the biological activity of modulators of multi-drug resistance
    • Wadkins RM and Houghton PJ: The role of drug-lipid interactions in the biological activity of modulators of multi-drug resistance. Biochim Biophys Acta 1153: 225-236, 1993.
    • (1993) Biochim Biophys Acta , vol.1153 , pp. 225-236
    • Wadkins, R.M.1    Houghton, P.J.2
  • 27
    • 0032763676 scopus 로고    scopus 로고
    • Relationship between cytotoxic activity and dipole moment for phthalimido- and chloroethyl-phenothiazines
    • Kurihara T, Motohashi N, Sakagami H and Molnár J: Relationship between cytotoxic activity and dipole moment for phthalimido- and chloroethyl-phenothiazines. Anticancer Res 19: 4081-4083, 1999.
    • (1999) Anticancer Res , vol.19 , pp. 4081-4083
    • Kurihara, T.1    Motohashi, N.2    Sakagami, H.3    Molnár, J.4
  • 29
    • 0026553782 scopus 로고
    • In vitro antiproliferative effects of tricyclic psychopharmaceutical, agents and synergism with some resistance modifiers
    • Molnár J, Tarodi B, Galfi M, Matkovics B and Motohashi N. In vitro antiproliferative effects of tricyclic psychopharmaceutical, agents and synergism with some resistance modifiers. Anticancer Res 12: 273-280, 1992.
    • (1992) Anticancer Res , vol.12 , pp. 273-280
    • Molnár, J.1    Tarodi, B.2    Galfi, M.3    Matkovics, B.4    Motohashi, N.5
  • 30
    • 0000080330 scopus 로고
    • The surface activity of tranquilizers
    • Seeman PM and Bialy HB: The surface activity of tranquilizers. Biochem Pharmacol 12: 1181-1191, 1963.
    • (1963) Biochem Pharmacol , vol.12 , pp. 1181-1191
    • Seeman, P.M.1    Bialy, H.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.