The use of plants in traditional medicine: Potential genotoxic risks

South African Journal of Botany

Volumn 68, Issue 3, 2002, Pages 408-410

  Elgorashi, E E ^a,b,c   Taylor, J L S ^a,b,c   Maes, A ^a   De Kimpe, Norbert ^b   Van Staden, J ^c   Verschaeve, Luc ^a  

^a FLEMISH INSTITUTE FOR TECHNOLOGICAL RESEARCH VITO   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

^c UNIVERSITY OF KWAZULU NATAL   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

MEDICINAL PLANT;

ANTIDESMA; ANTIDESMA VENOSUM; BACTERIA (MICROORGANISMS); BALANITES; BALANITES MAUGHAMII; CHAETACHME; CHAETACME ARISTATA; CROTON; CROTON SYLVATICUS; GARDENIA; GARDENIA VOLKENSII; PLUMBAGO AURICULATA; SPIROSTACHYS AFRICANA;

EID: 0036760780     PISSN: 02546299     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0254-6299(15)30409-9     Document Type: Article

References (14)

1. Benedict WF, Baker MS, Haroun E, Choi E, Ames BN (1977) Mutagenicity of cancer chemotherapeutic agents in Salmonella/microsome test. Cancer Research 37: 2209-2213
2. Eloff JN (2000) On expressing the antibacterial activity of plant extracts - A small first step in applying scientific knowledge to rural primary health care. South African Journal of Science 96: 116-118
3. Fabricant TS, Farnsworth NR (2001) The value of plants used in traditional medicine for drug discovery. Environmental Health Perspective 109: 69-75
4. Fenech M (2000) The in vitro micronucleus technique. Mutation Research 455: 81-95
5. Hutchings A, Scott AH, Lewis G, Cunningham A (1996) Zulu Medicinal Plants. University of Natal Press, Pietermaritzburg. ISBN 0 86980 893 1
6. Kassie F, Parzefall W, Musk S, Johnson I, Lamprecht G, Sontag G, Knasmuller S (1996) Genotoxic effects of crude juices from Brassica vegetables and juices and extracts from phytopharmaceutical preparations and spices of cruciferous plants origin in bacterial and mammalian cells. Chemico-Biological Interactions 102: 1-16
7. Maron DM, Ames BN (1983) Revised methods for the Salmonella mutagenicity test. Mutation Research 113: 173-215
8. Schimmer O, Kruger A, Paulini H, Haefele F (1994) An evaluation of 55 commercial plant extracts in the Ames mutagenicity test. Pharmazie: 448-451
9. Senio Y, Nagao M, Yahagi T, Hoshino A, Kawachi T, Sugimura T (1978) Mutagenicity of several classes of antitumor agents to Salmonella typhimurium TA98, TA100 and TA92. Cancer Research 38: 2148-2156
10. Singh NP, McCoy MT, Tice RR, Schneider EL (1988) A simple technique for quantitation of low levels of DNA damage in individual cells. Experimental Cell Research 175: 184-191
11. Van Hummelen P, Kitsch-Volders M (1990) An improved method for the in vitro micronucleus test using human lymphocytes. Mutagenesis 5: 203-204
12. Van Wyk B-E, Van Oudtshoorn B, Gericke N (1997) Medicinal Plants of South Africa. Briza Publication, Pretoria. ISBN 1 875093 09 5
13. Verschaeve L, Van Gompel J, Thilemans L, Regniers L, Vanparys P, Van der Lelie D (1999) VITOTOX® bacterial genotoxicity and toxicity test for the rapid screening of chemicals. Environmental and Molecular Mutagenesis 33: 240-248
14. Walker MJ (1999) The resurgence of natural medicine. The Ecologist 29: 226-228