Coma blisters, peripheral neuropathy, and amitriptyline overdose: A brief report

Journal of Cutaneous Medicine and Surgery

Volumn 6, Issue 5, 2002, Pages 438-441

  Maguiness, Sheilagh ^a   Guenther, Lyn ^a   Shum, David ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMITRIPTYLINE; BARBITURIC ACID DERIVATIVE; BENZODIAZEPINE; CLORAZEPATE DIPOTASSIUM; PARACETAMOL; SALICYLIC ACID; TRICYCLIC ANTIDEPRESSANT AGENT;

ADULT; ARTICLE; BLISTER; CASE REPORT; CLINICAL FEATURE; COMA; DRUG BLOOD LEVEL; DRUG MECHANISM; DRUG OVERDOSE; DRUG URINE LEVEL; ENDOTHELIUM; FEMALE; HUMAN; INFORMATION RETRIEVAL; MALE; MEDICAL LITERATURE; PERIPHERAL NEUROPATHY; PHYSICAL EXAMINATION; POLYPHARMACY; PRIORITY JOURNAL; CHEMICALLY INDUCED DISORDER; INTOXICATION; PATHOLOGY;

ADULT; AMITRIPTYLINE; ANTIDEPRESSIVE AGENTS, TRICYCLIC; BLISTER; COMA; FEMALE; HUMANS; OVERDOSE; PERIPHERAL NERVOUS SYSTEM DISEASES;

EID: 0036754883     PISSN: 12034754     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10227-001-0132-8     Document Type: Article

References (14)

1. Villaret ML, Bith H, Desoille M. Paris Med 1932; 2:340.
2. Larrey DJ. Memoires de Chirurgie Militaire et Campagnes, Vol 3. Paris: Smith and Buisson, 1812, p 13.
3. Sanchez Yus ES, Requena L, Simon P. Histopathology of cutaneous changes in drug-induced coma. Am J Dermatopathol 1993; 15(3):208-216.
4. Dunn C, Held J, Spitz J et al. Coma blisters: Report and review. Cutis 1990; 45:423-426.
5. Anonymous. Barbiturate coma and blisters [Letter]. Lancet April 1 1972; 1(7753):733.
6. Allen GE, Hadden DR. Barbiturate coma and blisters [Letter]. Lancet April 22 1972; 1(7756):904.
7. Borda I. Barbiturate coma bullae [Letter]. JAMA. 1970 Nov 23; 214(8):1564.
8. Herschthal D, Robinson MJ. Blisters of the skin in coma induced by amitriptyline and Clorazepate dipotassium. Report of a case with underlying sweat gland necrosis. Arch Dermatol April 1979; 115(4):499.
9. Reilly GD, Harrington CI. Positive immunofluorescence in bullous lesions in drug-induced coma. Br J Dermatol 1983; 109: 720
10. Fogarty BJ, Khan K. Drug induced blistering and the plastic surgeon: A case of amitriptyline induced skin necrosis. Burns 1999; 25(8):768-770.
11. Mehregan DR, Daoud M, Rogers R. Coma blisters in a patient with diabetic ketoacidosis. J Am Acad Dermatol 1992: 27(2):269-270.
12. Holden CEA. Cutaneous bullae in coma due to poisoning: An association with deep seated ischaemic lesions of muscle. Anesthesia 1977; 32:544-545.
13. Dahlin KL, Bohlin K, Strindlund J et al. Amitriptyline-induced loss of tight junction integrity in a human endothelial-smooth muscle cell bi-layer model. Toxicology 1999; 136:1-13.
14. Sheilds RW, Root KE, Wilbourn AJ. Compartment syndromes and compression neuropathies in coma. Neurology 1986; 36:1370-1374.