Amitriptyline-induced loss of tight junction integrity in a human endothelial-smooth muscle cell bi-layer model

Toxicology

Volumn 136, Issue 1, 1999, Pages 1-13

  Dahlin, Karin L ^a   Bohlin, Käth ^a   Strindlund, Jennie ^a   Ryrfeldt, Åke ^a   Cotgreave, Ian A ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

ARDS; Cell permeability; Cytotoxicity; Membrane fluidity; Tight junction; Tricyclic antidepressants

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; AMITRIPTYLINE; DESIPRAMINE; IMIPRAMINE; NORTRIPTYLINE; TRICYCLIC ANTIDEPRESSANT AGENT;

ADULT RESPIRATORY DISTRESS SYNDROME; ANISOTROPY; ARTICLE; CELL STRUCTURE; CELL VIABILITY; COCULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; ELECTRIC RESISTANCE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LIPOPHILICITY; MEMBRANE FLUIDITY; PERMEABILITY; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; TIGHT JUNCTION; UMBILICAL CORD;

AMITRIPTYLINE; ANTIDEPRESSIVE AGENTS, TRICYCLIC; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; CELLS, CULTURED; COCULTURE TECHNIQUES; DESIPRAMINE; ELECTRIC IMPEDANCE; ENDOTHELIUM, VASCULAR; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; FORMAZANS; HUMANS; IMIPRAMINE; MUSCLE, SMOOTH, VASCULAR; NORTRIPTYLINE; SPECTROMETRY, FLUORESCENCE; TETRAZOLIUM SALTS; TIGHT JUNCTIONS; UMBILICAL CORD;

EID: 0032779175     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(99)00035-9     Document Type: Article

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