Interleukin-4 induces apoptosis in cultured human follicular keratinocytes, but not in dermal papilla cells

European Journal of Dermatology

Volumn 12, Issue 5, 2002, Pages 432-438

  Mandt, Nathalie ^a   Geilen, Christoph C ^a   Wrobel, Anna ^a   Gelber, Alexandra ^a   Kamp, Hartwig ^a   Orfanos, Constantin E ^a   Blume Peytavi, Ulrike ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Apoptosis; Bax; Bcl 2; Dermal papilla cells; Follicular keratinocytes; IL 4

Indexed keywords

COMPLEMENTARY DNA; CYTOKINE; GROWTH FACTOR; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 4; PROTEIN BAX; PROTEIN BCL 2; RNA; STAUROSPORINE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DERMIS; HAIR FOLLICLE; HAIR GROWTH; HUMAN; HUMAN CELL; KERATINOCYTE; NUCLEOTIDE SEQUENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

APOPTOSIS; BASE SEQUENCE; CELLS, CULTURED; CYTOKINES; DERMIS; EPIDERMAL GROWTH FACTOR; FEMALE; FIBROBLASTS; HAIR FOLLICLE; HUMANS; IN SITU NICK-END LABELING; INTERLEUKIN-4; KERATINOCYTES; MALE; MOLECULAR SEQUENCE DATA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; STAUROSPORINE;

EID: 0036751244     PISSN: 11671122     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Cotsarelis G, Sun TT, Lavker R. Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle and skin carcinogenesis. Cell 1990; 61: 1329-37.
2. Olson RL, Everett MA. Epidermal apoptosis: cell deletion by phagocytosis. J Cutan Pathol 1975; 2: 53-7.
3. Weedon D, Strutton G. Apoptosis as the mechanism of the involution of hair follicles in catagen transformation. Acta Derm Venereal 1981; 61: 335-9.
4. Lindner G, Botchkarev VA, Botchkareva NV, et al. Analysis of apoptosis during hair follicle regression (catagen). Am J Pathol 1997; 151: 1601-15.
5. Matsuo K, Mori O, Hashimoto T. Apoptosis in murine hair follicles during catagen regression. Arch Dermatol Res 1998; 290: 133-6.
6. Jindo T, Imai R, Tsuboi R, et al. The effect of various cytokines on hair growth of mouse vibrissae in organ culture. J Dermatol Sci 1994; 7 (suppl.): 73S-8S.
7. Hoffmann R, Eicheler W, Huth A, et al. Cytokines and growth factors influence hair growth in vitro. Possible implications for the pathogenesis and treatment of alopecia areata. Arch Dermatol Res 1996; 288: 153-6.
8. Philpott M, Sanders D, Bowen J, Kealey T. Effects of interleukins, colony stimulating factor and tumor necrosis factor on human hair follicle growth in vitro: a possible role for interleukin-1 and tumor necrosis factor-α in alopecia areata. Br J Dermatol 1996; 135: 942-8.
9. Seiberq M, Marthinus J, Stenn KS. Changes of expression of apoptosis-assoicated genes in skin mark early catagen. J Invest Dermatol 1995; 104: 78-82.
10. Goerdt S, Orfanos CE. Other functions, other genes: alternative activation of antigen-presenting cells, Immunity 1999; 10: 137-42.
11. Clerici M, Fusi ML, Ruzzante S, et al. Type 1 and type 2 cytokines in HIV-infection: a possible role in apoptosis and disease progression. Ann Med 1997; 29: 185-8.
12. Westgate G, Craggs R, Gibson W. Immune privilige in hair growth. J Invest Dermatol 1991; 97: 156-9.
13. Ferraris C, Cooklis M, Polakowska R, Haake A. Induction of apoptosis through the PKC pathway in cultured dermal papilla fibroblasts. Exp Cell Res 1997; 234: 37-46.
14. Hockenbery D, Zoltan NO, Xiao-Ming Y, et al. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 1993; 75: 241-51.
15. Carson DA, Ribeiro JM. Apoptosis and disease. Lancet 1993; 341: 1251-4.
16. Detmar M, Schaart FM, Blume U, Orfanos CE. Culture of hair matrix and follicular keratinocytes. J Invest Dermatol 1993; 101 (suppl.): 130S-4S.
17. Jahoda C, Horne K, Oliver R. Inductian of hair growth by implantation of cultured dermal papilla cells. Nature 1984; 311: 560-2.
18. Hoffmann R, Eicheler W, Wenzel E, Happle R. Interleukin-1 β-induced inhibiton of hoir growth is mediated by cyclic AMP. J Invest Dermatol 1997; 108: 40-2.
19. Xiong Y, Harmon CS. Interleukin-1 beta is differentially expressed by human dermal papilla cells in response to PKC activation and is a potent inhibitor of human hair follicle growth in organ culture. J Int Cyt Res 1997; 17: 151-7.
20. Stenn K, Eilertsen K. Molecular basis of hair growth control. J Invest Dermatol 1996; 107: 669-70.
21. Ahmed AA, Nordlind K, Schultzberg M, et al. Immunohistochemical studies of proinflammatory cytokines and their receptors in hair follicles of normal human skin. Acta Derm Venereol 1996; 76: 348-52.
22. Chiu HC, Chang CH, Chen JS, Jee SH. Human hair follicle dermal papilla cell, dermal sheath cell and interstitial dermal fibroblast characteristics. J Formos Med Assoc 1996; 95: 667-74.
23. Danilenko DM, Ring BD, Pierce GF. Growth factors and cytokines in hair follicle development and cycling: recent insights from animal models and the potentials for clinical therapy. Mol Med Today 1996; 2: 460-7.
24. Jahoda CAB. Cellular and developmental aspects of androgenetic alopecia. Exp Dermatol 1998; 7: 235-48.
25. Kock A, Schwartz T, Kirnbauer R, et al. Human keratinocytes are a source of tumor necrosis factor α: evidence for synthesis upon stimulation. J Exp Med 1990; 172: 1609-14.
26. Lachgar S, Charveron M, Gall Y, et al. Vascular endothelial cells: targets for studying the activity of hair follcile cell-produced VEGF. Cell Biol Toxicol 1996; 12: 331-4.
27. Little J, Redwood K, Granger S, Jenkins G. In vivo cytokine and receptor gene expression during the rat hair growth cycle. Analysis by semiquantitaive RT-PCR. Exp Dermatol 1996; 5: 202-12.
28. Mahé YF, Buan B, Billoni N, et al. Pro-inflammatory cytokine cascade in human plucked hair. Skin Pharmacol 1996; 9: 366-75.
29. Panaretto BA. Gene expression of potential morphogens during hair follicle and tooth formation. Reprod Fert Dev 1993; 5: 345-60.
30. Paus R, Foitzik K, Welker P, et al. Transforming growth factor-β receptor type I and type II expression during murine hair follicle development and cycling. J Invest Dermatol 1997; 109: 518-26.
31. Philpott M, Sanders D, Westgate G, Kealey T. Human hair growth in vitro: a model for the study of hair follicle biology. J Dermatol Sci 1994; 7 (suppl.): 55S-72S.
32. Takata Y, Seki S, Dobashi H, et al. Inhibtion of IL-12 synthesis of peripheral blood mononuclear cells (PBMC) stimulated with a bacterial super-antigen by pooled human immunoglobulin: implications for its effect on Kawasaki disease (KD). Clin Exp Immunol 1998 114: 311-9.
33. Terenghi G, Mann D, Kopelman PG, Anand P. TrkA and trkC expression is increased in human diabetic skin. Neurosci Lett 1997; 228: 33-6.
34. Westgate G, Little J, Philpott M, et al. A new model of hair growth regulation. 19th IFSCC Congress, Sydney 1996 3: 99-113.
35. Blume-Peytavi U. Die Kontrolle des Haarzyklus: Funktion und Bedeutung der dermalen Papille. Z Hautkr 1996; 71: 410-5.
36. Kozlowska U, Blume-Peytavi U, Kodelja V, et al. Expression of vascular endothelial growth factor (VEGF) in various compartments of the human hair follicle. Arch Dermatol Res 1998; 290: 661-8.
37. Kozlowska U, Blume-Peytavi U, Kodel a V, et al. Vascular endothelial growth factor induced by proinflammatory cytokines (interleukin-1α, β) in cells of the human pilosebaceous unit. Dermatology 1998; 196: 89-92.
38. Messenger AG. The control of hair growth: an overview. J Invest Dermatol 1993; 101 (suppl.): 4S-9S.
39. Freyschmidt-Paul P, Sundberg JP, Happle R, et al. Successful treatment of alopecia areata-like hair loss with the contact sensitizer squaric acid dibutylester (SADBE) in C3H/HeJ mice. J Invest Dermatol 1999; 113: 61-8.
40. Veis D, Sorenson JCM, Shutter JR, et al. Bcl-2 defficient mice demonstrate fulminant lymphoid apoptosis, palycystic kidneys, and hypopigmented hair. Cell 1993; 75: 229-40.
41. Purl RK, Siegel JP. Interleukin-4 and cancer therapy. Cancer Invest 1993; 11: 479-86.
42. Varricchio F, Husain SR, Leland P, et al. Intedeukin-4 receptor expression in vivo on human AIDS-related kaposi's sarcoma. Oncol Res 1997; 9: 495-503.
43. Opal SM, DePalo V. Anti-inflammatory cytokines. Chest 2000; 117: 1162-72.
44. Foitzik K, Lindner G, Mueller-Roever S, et al. Control of murine hair follicle regression (catagen) by TGF-beta1 in vivo. FASEB J 2000; 14: 752-60.
45. De Tran QH, Guay E, Chartier S, et al. Tracolimus in dermatology. J Cutan Med Surg 2001; 5: 329-35.
46. Yoshino T, Asada H, Ando Y, et al. Impaired responses of peripheral blood mononuclear cells to stimulants in alopecia areata patients with a poor response to topical immunotherapy. Br J Dermatol 2001; 145: 415-21.