Effects of interleukins, colony-stimulating factor and tumour necrosis factor on human hair follicle growth in vitro: A possible role for interleukin-1 and tumour necrosis factor-α in alopecia areata

British Journal of Dermatology

Volumn 135, Issue 6, 1996, Pages 942-948

  Philpott, M P ^a   Sanders, D A ^a   Bowen, J ^b   Kealey, T ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b NONE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COLONY STIMULATING FACTOR; INTERLEUKIN 1; TUMOR NECROSIS FACTOR ALPHA;

ALOPECIA; ARTICLE; DOSE RESPONSE; HAIR FOLLICLE; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNE SYSTEM; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

EID: 0029858059     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2133.1996.d01-1099.x     Document Type: Article

References (38)

1. Pinkus H. Embryology of the hair. In: The Biology of Hair Growth (Montagna W, Ellis RA, eds). New York: Academic Press, 1958: 1-32.
2. Ansel J, Perry P, Brown J et al. Cytokine modulation of keratinocyte cytokines. J Invest Dermatol 1990; 94 (Suppl.): 1015-75.
3. Hancock GE, Kaplan G, Cohn ZA. Keratinocyte growth regulation by the products of immune cells. J Exp Med 1988; 168: 1395-402.
4. Cork MJ, Mee JB, Duff GW. Cytokines. In: Molecular Aspects of Dermatology (Priestly GC, ed.). Chichester: John VViley and Sons, 1993: 129-46.
5. Whicher JT, Evans SW. Cytokines in disease. Clin Chem 1990; 36: 1269-81.
6. Sporn MB, Roberts AB. Peptide growth factors are multifunctional. Nature 1988; 332: 217-19.
7. Harper JI, Kendra JR, Desai S et al. Dermatological apsects of the use of cyclosporin A for prophylaxis of graft-versus-host disease. Br J Dermatol 1984; 110: 469-74.
8. Pendry A, Alexander P. Stimulation of hair growth on nude mice by cyclosporin A. In: Cyclosporine A (White DJG, ed.). Amsterdam: Elsevier Biomedical Press: 1982; 77.
9. Sawada M, Terada N, Taniguchi H, Tateishi R, Mori Y. Cyclosporin A stimulates hair growth in nude mice. Lab Invest 1987; 56: 684-6.
10. Westgate GE, Craggs RI, Gibson WT. Immune privilege in hair growth. Invest Dermatol 1991; 97: 417-20.
11. Taylor M, Ashcroft ATT, Messenger AG. Cyclosporin A prolongs human hair growth in vitro. J Invest Dermatol 1993; 100: 237-9.
12. Galbraith GMP, Thiers BH, Vasily DB, Fudenberg HH. Immunohistological profile of alopecia areata. Br J Dermatol 1984; 110: 163-70.
13. Messenger AG, Slater DN, Bleehen SS. Alopecia areata: alterations in the hair growth cycle and correlation with the follicular pathology. Br J Dermatol 1986; 114: 337-47.
14. Macdonald-Hull S, Nutbrown M, Pepall I, et al. Immunhohistologic and ultrastructural comparison of the dermal papilla and hair follicle bulb from 'active' and 'normal' areas of alopecia areata. J Invest Dermatol 1991; 96: 673-81.
15. Hussein AM, Jimenez JJ, McCall CA, Yunis AA. Protection from chemotherapy-induced alopecia in a rat model. Science 1990; 249: 1564-6.
16. Jimenez JJ, Wong GHW, Yunis AA. Interleukin 1 protects from cytosine arabinoside-induced alopecia in the rat model. FASEB J 1991; 5: 2456-8.
17. Hussein AM. Interleukin 1 protects against l-3-D-arabinofuranosylcytosine-induced alopecia in the newborn rat animal model. Cancer Res 1991; 51: 3329-30.
18. Harmon CS, Nevins TD. IL-1α inhibits human hair follicle growth and hair fiber production in whole organ culture. Lymphokine Cytokine Res 1993; 12: 197-203.
19. Westgate GE, Gibson WT, Kealey T, Philpott MP. Prolonged maintenance of isolated human hair follicles in a serum free defined medium. Br J Dermatol 1993; 129: 372-9.
20. Philpott MP, Kealey T. The effects of EGF on the morphology and patterns of DNA synthesis in freshly isolated and maintained human hair follicles. J Invest Dermatol 1994; 102: 186-91.
21. Hollis DE, Chapman RE, Panaretto BA, Moore GPM. Morphological changes in the skin and wool fibres of Merino sheep infused with epidermal growth factor. Aust J Biol Sci 1983; 36: 419-34.
22. Philpott MP, Sanders DA, Kealey T. The effects of insulin and insulin like growth factors on cultured human hair follicles: IGF-1 at physiological concentrations is an important regulator of hair follicle growth in vitro. J Invest Dermatol 1994; 102: 857-61.
23. Messenger AG, Bleehen SS. Alopecia areata: light and electron microscopic pathology of the regrowing white hair. Br J Dermatol 1984; 110: 155-62.
24. Nutbrown M, MacDonald Hull SP, Cunliffe WJ, Randall VA. Abnormalities in the ultrastructure of melanocytes and outer root sheath of clinically normal hair follicles from alopecia areata scalps. J Invest Dermatol 1995; 104: 12S.
25. Kristensen M, Deleuran B, Eedy DJ et al. Distribution of interleukin 1 receptor antagonist protein (IRAP), interleukin 1 receptor, and interleukin 1α in normal and psoriatic skin. Decreased expression of IRAP in psoriatic lesional epidermis. Br J Dermatol 1992; 127: 305-11.
26. Tarlow JK, Clay FE, Cork MJ et al. Severity of alopecia areata is associated with a polymorphism in the interleukin-1 receptor antagonist gene. J Invest Dermatol 1994; 103: 387-90.
27. Cork MJ, Tarlow JK, Clay FE et al. An allele of the interleukin-1 receptor antagonist as a genetic severity factor in alopecia areata. J Invest Dermatol 1995; 104: 15S.
28. Mee JB, Cork MJ, di Giovivni FS et al. Cytokine gene activation across the advancing edge of psoriatic plaques. J Invest Dermatol 1993; 101: 389A.
29. Hammerberg C, Arend WP, Fisher CJ et al. Interleukin-1 receptor antagonist in normal and psoriatic epidermis. J Clin Invest 1992; 90: 571-83.
30. McDonagh AJG, Al' Abadie MSK, Symons JA et al. Cytokine production by dermal papilla cell cultures in alopecia areata. J Invest Dermatol 1993; 100: 569A.
31. Pannica N, Nedwin GE, Hayflick JS et al. Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin. Nature 1984; 312: 724-9.
32. Balkwill FR. Tumour necrosis factor. Br Med Bull 1989; 45: 389-400.
33. Symington FW. Lymphotoxin, tumour necrosis factor and gamma interferon are cytostatic for normal human keratinocytes. J Invest Dermatol 1989; 94: 798-805.
34. Kapp A, Zeck-Kapp G, Blohm D. Human tumour necrosis factor is a potent activator of the oxidative metabolism in human polymorphonuclear neutrophilic granuloyctes: comparison with human lymphotoxin. J Invest Dermatol 1989; 92: 348-54.
35. McDonagh AJG, Snowden JA, Stierle C et al. HLA and ICAM-1 expression in alopecia areata in vivo and in vitro: the role of cytokines. Br J Dermatol 1993; 129: 250-6.
36. Morhenn VB, Wood GS. Gamma interferon-induced expression of class II major histocompatability complex antigens by human keratinocytes. Ann NY Acad Sci USA 1988; 548: 321-30.
37. Baker BS, Powles AV, Valdimarsson H, Fry L. An altered response of psoriatic keratinocytes to gamma interferon. Scand J Immunol 1988; 28: 735-40.
38. Paus R, Link RE. The psoriatic epidermal lesion and hair growth may share the same 'switch-on' mechanism. Yale J Biol Med 1988; 61: 467-76.