ATP-induced internalization of amphibian epithelial P2X receptors is linked to channel opening

Pflugers Archiv European Journal of Physiology

Volumn 444, Issue 6, 2002, Pages 795-800

  Jensik, Phil ^a   Cox, Thomas ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Amiloride; Amphibian; Endocytosis; Epithelial transport; Purinergic; Sodium

Indexed keywords

ADENOSINE TRIPHOSPHATE; CATION CHANNEL; GREEN FLUORESCENT PROTEIN; PURINE P2X RECEPTOR; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; SURAMIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; ENDOCYTOSIS; FLUORESCENCE; INTERNALIZATION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; VOLTAGE CLAMP; XENOPUS;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELL MEMBRANE; ENDOCYTOSIS; EPITHELIAL CELLS; GREEN FLUORESCENT PROTEINS; INDICATORS AND REAGENTS; ION CHANNEL GATING; LUMINESCENT PROTEINS; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MUTAGENESIS, SITE-DIRECTED; OOCYTES; RECEPTORS, PURINERGIC P2; XENOPUS;

EID: 0036750680     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00424-002-0881-2     Document Type: Article

References (17)

1. Bo X, Schoepfer R, Burnstock G (2000) Molecular cloning and characterization of a novel ATP P2X receptor subtype from embryonic chick skeletal muscle. J Biol Chem 275:14401-14407
2. Boue-Grabot E, Akimenko MA, Seguela P (2000) Unique functional properties of a sensory neuronal P2X ATP-gated channel from zebrafish. J Neurochem 75:1600-1607
3. Chapell R, Bueno OF, Alvarez-Hernandez X, Robinson LC, Leidenheimer NJ (1998) Activation of protein kinase C induces gamma-aminobutyric acid type A receptor internalization in Xenopus oocytes. J Biol Chem 273:32595-32601
4. Cox T (1997) Apical regulation of nonselective cation channels by ATP in larval bullfrog skin. J Exp Zool 279:220-227
5. Dutton JL, Poronnik P, Li GH, Holding CA, Worthington RA, Vandenberg RJ, Cook DI, Barden JA, Bennett MR (2000) P2X(1) receptor membrane redistribution and down-regulation visualized by using receptor-coupled green fluorescent protein chimeras. Neuropharmacology 39:2054-2066
6. Ennion SJ, Evans RJ (2001) Agonist-stimulated internalisation of the ligand-gated ion channel P2X(1) in rat vas deferens. FEBS Lett 489:154-158
7. Holbird D, Jensik P, Cox T (2001) Aldosterone upregulates purinergic responses in larval amphibian skin epithelium. J Comp Physiol [B] 171:413-420
8. Jensik PJ, Holbird D, Collard MW, Cox TC (2001) Cloning and characterization of a functional P2X receptor from larval bullfrog skin. Am J Physiol 281:C954-C962
9. Khakh BS, Burnstock G, Kennedy C, King BF, North RA, Seguela P, Voigt M, Humphrey PP (2001) International union of pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits. Pharmacol Rev 53:107-118
10. Khakh BS, Smith WB, Chiu CS, Ju D, Davidson N, Lester HA (2001) Activation-dependent changes in receptor distribution and dendritic morphology in hippocampal neurons expressing P2X2-green fluorescent protein receptors. Proc Natl Acad Sci USA 98:5288-5293
11. Langloh ALB, Berdiev B, Ji H, Keyser K, Stanton BA, Benos DJ (2000) Charged residues in the M2 region of alpha-hENaC play a role in channel conductance. Am J Physiol 278:C277-C291
12. Li GH, Lee EM, Blair D, Holding C, Poronnik P, Cook DI, Barden JA, Bennett MR (2000) The distribution of P2X receptor clusters on individual neurons in sympathetic ganglia and their redistribution on agonist activation. J Biol Chem 275:29107-29112
13. North RA, Surprenant A (2000) Pharmacology of cloned P2X receptors. Annu Rev Pharmacol Toxicol 40:563-580
14. Ruppelt A, Ma W, Borchardt K, Silberberg SD, Soto F (2001) Genomic structure, developmental distribution and functional properties of the chicken P2X(5) receptor. J Neurochem 77:1256-1265
15. Subramanian VS, Marchant JS, Parker I, Said HM (2001) Intracellular trafficking/membrane targeting of human reduced folate carrier expressed in Xenopus oocytes. Am J Physiol 281:G1477-G1486
16. Torres GE, Haines WR, Egan TM, Voigt MM (1998) Co-expression of P2X1 and P2X5 receptor subunits reveals a novel ATP-gated ion channel. Mol Pharmacol 54:989-993
17. Valentijn JA, Fyfe GK, Canessa CM (1998) Biosynthesis and processing of epithelial sodium channels in Xenopus oocytes. J Biol Chem 273:30344-30351