Human pregnancy-specific glycoprotein 1a (PSG1a) induces alternative activation in human and mouse monocytes and suppresses the accessory cell-dependent t cell proliferation

Journal of Leukocyte Biology

Volumn 72, Issue 3, 2002, Pages 512-521

  Motrán, Claudia Cristina ^a   Díaz, Fernando López ^a   Gruppi, Adriana ^a   Slavin, Daniela ^a   Chatton, Bruno ^b   Bocco, José Luis ^a  

^a UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

^b UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Arginase; Immunosuppression; iNOS

Indexed keywords

GLYCOPROTEIN; NITRIC OXIDE; POLYPEPTIDE; PREGNANCY ASSOCIATED PROTEIN; PREGNANCY SPECIFIC GLYCOPROTEIN 1A; RECOMBINANT PROTEIN; SUPPRESSOR FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN SPECIFICITY; ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CONTROLLED STUDY; EXPRESSION VECTOR; FEMALE; HUMAN; HUMAN CELL; IMMUNOMODULATION; MACROPHAGE ACTIVATION; MAMMAL CELL; METABOLIC REGULATION; MITOSIS INHIBITION; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; T LYMPHOCYTE ACTIVATION;

ANIMALS; ARGINASE; CELL CYCLE; CELL DIVISION; CELL LINE; CONCANAVALIN A; ENZYME INDUCTION; FEMALE; GLYCOSYLATION; HELA CELLS; HUMANS; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; LYMPHOCYTE CULTURE TEST, MIXED; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED BALB C; MONOCYTES; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PREGNANCY; PREGNANCY-SPECIFIC BETA 1-GLYCOPROTEINS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT FUSION PROTEINS; T-LYMPHOCYTE SUBSETS;

ANIMALIA; MAMMALIA; MURINAE; VECTORS;

EID: 0036746116     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (59)

1. Medawar, P. B. (1953) Some immunological and endocrinological problems raised by evolution of viviparity in vertebrates. Symp. Soc. Exp. Biol. 7, 320-328.
2. Matthiesen, L., Berg, G., Ernerudh, J., Hakansson, L. (1996) Lymphocyte subsets and mitogen stimulation of blood lymphocytes in normal pregnancy. Am. J. Reprod. Immunol. 35, 70-79.
3. Bermas, B. L., Hill, J. A. (1997) Proliferative responses to recall antigens are associated with pregnancy outcome in women with a history of recurrent spontaneous abortion. J. Clin. Investig. 100, 1330-1334.
4. Porcu, P., Gaddy, J., Broxmeyer, H. E. (1998) Alloantigen-induced unresponsiveness in cord blood T lymphocytes is associated with defective activation of Ras. Proc. Natl. Acad. Sci. USA 95, 4538-4543.
5. Wegmann, T. G., Lin, H., Guilbert, L., Mosmann, T. R. (1993) Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon? Immunol. Today 14, 353-356.
6. Sacks, G., Sargent, I., Redman, C. (1999) An innate view of human pregnancy. Immunol. Today 20, 114-118.
7. Goerdt, S., Orfanos, C. E. (1999) Other functions, other genes: alternative activation of antigen-presenting cells. Immunity 10, 137-142.
8. Stein, M., Keshav, S., Harris, N., Gordon, S. (1992) Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J. Exp. Med. 176, 287-292.
9. Munder, M., Eichmann, K., Modolell, M. (1998) Alternative metabolic states in murine macrophage reflected by the nitric oxide synthase/arginase balance in mouse bone marrow-derived macrophages by Th1 and Th2 cytokines. Eur. J. Immunol. 25, 1101-1104.
10. Mues, B., Langer, D., Zwadlo, G., Sorg, C. (1989) Phenotypic characterization of macrophages in human term placenta. Immunology 67, 303-307.
11. Cua, D. J., Stohlman, S. A. (1997) In vivo effects of T helper cell type 2 cytokines on macrophage antigen-presenting cell induction of T helper subsets. J. Immunol. 159, 5834-5840.
12. Loke, P., MacDonald, A. S., Allen, J. (2000) Antigen-presenting cells recruited by Brugia malayi induce Th2 differentiation of naïve CD4+ T cells. Eur. J. Immunol. 30, 1127-1135.
13. Mellor, A. L., Munn, D. H. (2000) Immunology at the maternal-fetal interface: lessons for T cell tolerance and suppression. Annu. Rev. Immunol. 18, 367-391.
14. Djian, V., Menu, E., Thibault, G., Ropert, S., Chaouat, G. (1996) Immunoactive products of placenta. V. Immunoregulatory properties of a low molecular weight compound obtained from human placental cultures. Am. J. Reprod. Immunol. 36, 11-24.
15. Krishnan, L., Sad, R. S., Raghupathy, R. (1995) Characterization of an immunosuppressive factor secreted by a human trophoblast-derived choriocarcinoma cell line. Cell. Immunol. 162, 295-308.
16. Markert, U. R., Chaouat, G. (1997) Preliminary characterization of an immunosuppressive inducer factor secreted by the JEG-3 choriocarcinoma cell line: in vitro and in vivo studies. Am. J. Reprod. Immunol. 38, 327-338.
17. Horne, C. H., Towler, C. M., Pugh-Humphreys, R. G., Thomson, A. W., Bohn, H. (1976) Pregnancy specific beta1-glycoprotein - a product of the syncytiotrophoblast. Experientia 32, 1197.
18. Watanabe, S., Chou, J. Y. (1988) Isolation and characterization of complementary DNAs encoding human pregnancy-specific beta 1-glycoprotein. J. Biol. Chem. 263, 2049-2054.
19. Teglund, S., Zhou, G. Q., Hammerstrom, S. (1995) Characterization of cDNA encoding novel pregnancy-specific glycoprotein variants. Biochem. Biophys. Res. Commun. 211, 656-664.
20. Bohn, H. (1971) Detection and characterization of pregnancy proteins in the human placenta and their quantitative immunochemical determination in sera from pregnant women. Arch. Gynakol. 210, 440-457.
21. Lin, T. M., Halbert, S. P., Kiefer, D. (1976) Quantitative analysis of pregnancy-associated plasma proteins in human placenta. J. Clin. Investig. 57, 466-472.
22. Masson, G. M., Anthony, F., Wilson, M. (1983) Value of Schwangerschftsprotein 1 (SP1) and pregnancy-associated plasma protein A (PAPP-A) in the clinical management of threatened abortion. Br. J. Obstet. Gynaecol. 90, 146-149.
23. Silver, R. M., Heyborne, K. D., Leslie, K. K. (1993) Pregnancy specific beta 1 glycoprotein (SP-1) in maternal serum and ammiotic fluid; preeclampsia, small for gestational age fetus and fetal distress. Placenta 14, 583-589.
24. Tamsen, L., Johansson, S. G., Axelsson, O. (1983) Pregnancy-specific beta 1-glycoprotein (SP1) in serum from women with pregnancies complicated by intrauterine growth retardation. J. Perinat. Med. 11, 19-25.
25. Arnold, L. L., Doherty, T. M., Flor, A. W., Simon, J. A., Chou, J. Y., Chan, W. Y., Mansfield, B. C. (1999) Pregnancy-specific glycoprotein gene expression in recurrent aborters: a potential correlation to interleukin-10 expression. Am. J. Reprod. Immunol. 41, 174-182.
26. Blanchon, L., Bocco, J. L., Gallot, D., Gachon, A., Lemery, D., Dechelotte, P., Dastugue, B., Sapin, V. (2001) Co-localization of KLF6 and KLF4 with pregnancy-specific glycoproteins during human placenta development. Mech. Dev. 105, 185-189.
27. Rutherfurd, K. J., Chou, J. Y., Mansfield, B. C. (1995) A motif in PSG11s mediates binding to a receptor on the surface of the pro-monocyte cell line THP-1. Mol. Endocrinol, 9, 1297-1305.
28. Waterhouse, R., Ha, C., Dveksler, G. S. (2002) Murine CD9 is the receptor for pregnancy-specific glycoprotein 17. J. Exp. Med. 195, 277-282.
29. Wessells, J., Wessner, D., Parsells, R., White, K., Finkenzeller, D., Zimmermann, W., Dveksler, G. (2000) Pregnancy specific glycoprotein 18 induces IL-10 expression in murine macrophages. Eur. J. Immunol. 30, 1830-1840.
30. Snyder, S. K., Wessner, D. H., Wessells, J. L., Waterhouse, R. M., Wahl, L. M., Zimmermann, W., Dveksler, G. S. (2001) Pregnancy-specific glycoproteins function as immunomodulators by inducing secretion of IL-10, IL-6 and TGF beta1 by human monocytes. Am. J. Reprod. Immunol. 45, 205-216.
31. Hara, T., Fu, S. M., Hansen, J. A. (1985) Human T cell activation II. A new activation pathway used by major T cell population via a disulfide bonded dimmer on a 44 kilodalton polypeptide (9.3 antigen). J. Exp. Med. 161, 1513-1518.
32. Wiktor, T. J., MacFarlan, R. I., Reagan, K. J., Dietzschold, B., Curtis, P. J., Wunner, W. H., Kieny, M. P., Lathe, R., Lecocq, J. P., Mackett, M., et al. (1992) Protection from rabies by a vaccinia virus recombinant containing the rabies virus glycoprotein gene. Biotechnology 24, 508-512.
33. Tartaglia, J., Cox, W. I., Taylor, J., Perkus, M., Riviere, M., Meignier, B., Paoletti, E. (1992) Highly attenuated poxvirus vectors. AIDS Res. Hum. Retroviruses 8, 1445-1447.
34. Nuñez, E., Aragón, C. (1994) Structural analysis and functional role of the carbohydrate component of glycine transporter. J. Biol. Chem. 269, 16920-16924.
35. Corraliza, I. M., Campo, M. L., Soler, G., Modolell, M. (1994) Determination of arginase activity in macrophages: a micromethod. J. Immunol. Methods 174, 231-235.
36. Nicoletti, Y., Migliorati, G., Pagliacci, M. C., Grignani, F., Riccardi, C. (1991) A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods 139, 271-279.
37. Sorensen, S. (1984) Pregnancy-"specific" beta 1-glycoprotein (SP1): purification, characterization, quantification and clinical application in malignancies (a review). Tumour Biol. 5, 275-302.
38. Bocco, J. L., Panzetta, G., Flury, A., Patrito, L. C. (1989) Expression of pregnancy specific beta 1-glycoprotein gene in human placenta and hydatiform mole. Biochem. Int. 18, 999-1008.
39. Morris Jr., S. M., Kepka-Lenhart, D., Chen, L. C. (1998) Differential regulation of arginases and inducible nitric oxide synthase in murine macrophage cells. Am. J. Physiol. 275, E740-E747.
40. Bertholet, S., Tzeng, E., Felley-Bosco, E., Mauel, J. (1999) Expression of the inducible NO synthase in human monocytic U937 cells allows high output nitric oxide production. J. Leukoc. Biol. 65, 50-58.
41. Palacios, R. (1985) Mechanisms by which accessory cells contribute in growth of resting T lymphocytes initiated by OKT3 antibody. Eur. J. Immunol. 15, 645-651.
42. Lipsky, P. E., Rosenthal, A. S. (1973) Macrophage-lymphocyte interaction. I. Characteristics of the antigen-independent-binding of guinea pig thymocytes and lymphocytes to syngeneic macrophages. J. Exp. Med. 138, 900-924.
43. Loke, P., MacDonald, A. S., Robb, A., Maizels, R. M., Allen, J. E. (2000) Alternatively activated macrophages induced by nematode infection inhibit proliferation via cell-to-cell contact. Eur. J. Immunol. 9, 2669-2678.
44. Namagala, B., Baetselier, P., Noël, W., Brys, L., Beschin, A. (2001) Alternative versus classical macrophage activation during experimental African tripanosomosis. J. Leukoc. Biol. 69, 387-396.
45. Banchereau, J., Steinman, R. M. (1998) Dendritic cells and the control of immunity. Nature 392, 245-252.
46. Weiner, C. P., Knowles, R. G., Stegink, L. D., Dawson, J., Moncada, S. (1996) Myometrial arginase activity increases with advancing pregnancy in guinea pig. Am. J. Obstet. Gynecol. 174, 779-782.
47. Remesar, X., Arola, L., Palou, A., Alemany, M. (1984) Arginase activity during pregnancy and lactation. Horm. Metab. Res. 16, 468-470.
48. Mendez, J. D., Yanez, R., Wong, C., Hicks, J. J. (1986) Uterine arginase inhibition affect the rat embryonic development. Contraception 33, 597-604.
49. Chamorro, G., Salazar, M., Salazar, S., Trujillo, J., Munoz, O., Yanez, R. (1996) Antifertility effects of (+)-S-2-amino-6-iodoacetamidohexanoic acid (2-AIHA) in female rats. Contraception 53, 247-251.
50. Lowe, D. T. (2000) Nitric oxide dysfunction in the pathophysiology of preeclampsia. Nitric Oxide 4, 441-458.
51. Faxen, M., Nisell, H., Kublickiene, K. R. (2001) Altered mRNA expression of ecNOS and iNOS in myometrium and placenta of women with preeclampsia. Arch. Gynecol. Obstet. 265, 45-50.
52. Harris, S. J., Anthony, F. W., Jones, D. B., Masson, G. M. (1984) Pregnancy-specific B1-glycoprotein: effect on lymphocyte proliferation in vitro. J. Reprod. Immunol. 6, 267-270.
53. Cerni, C., Tatra, G., Bohn, H. (1977) Immunosuppression by human placental lactogen (HPL) and pregnancy-specific B1-glycoprotein (SP1). Arch. Gynakol. 233, 1-8.
54. McChesney, M. B., Altman, A., Oldstone, M. B. (1998) Suppression of T lymphocyte function by measles virus is due to cell cycle arrest in G1. J. Immunol. 140, 1269-1273.
55. Naniche, D., Reed, S. I., Oldstone, M. B. A. (1999) Cell cycle arrest during measles virus infection: a Go-like block leads to suppression of retinoblastoma protein expression. J. Virol. 73, 1894-1901.
56. Rea, D., van Kooten, C., van Meijgaarden, K. E., Ottenhoff, T. H., Melief, C. J., Offringa, R. (2000) Glucocorticoids transform CD40-triggering of dendritic cells into an alternative activation pathway resulting in antigenpresenting cells that secrete IL-10. Blood 95, 3162-3167.
57. Bright, J. J., Kerr, L. D., Sriram, S. (1997) TGF beta inhibits IL-2 induced tyrosine phosphorylation and activation of Jak-1 and Stat 5 in T lymphocytes. J. Immunol. 159, 175-183.
58. Kehrl, J. H., Wakefield, L. M., Roberts, A., Jakowlew, B., Alvarez-Mon, S. M., Derynck, R., Sporn, M. B., Fauci, A. S. (1986) Production of TGF beta by human T lymphocytes and its potential role in the regulation of T cell growth. J. Exp. Med. 163, 1037-1050.
59. Kingsley, C. I., Karim, M., Bushell, A. R., Wood, K. J. (2002) CD25+ CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses. J. Immunol. 168, 1080-1086.