Solanum paniculatum L. (Jurubeba): Potent inhibitor of gastric acid secretion in mice

Phytomedicine

Volumn 9, Issue 6, 2002, Pages 508-514

  Mesia Vela, S ^a,b   Santos, M T ^a   Souccar, C ^a   Lima Landman, M T R ^a   Lapa, A J ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b Lab for Cell and Biochem Toxicol   (United States)

Author keywords

Antiacid; Antiulcer; Gastric acid secretion; Medicinal plant; Pylorus ligature; Solanaceae; Solanum paniculatum

Indexed keywords

BETHANECHOL; INDOMETACIN;

ACIDIFICATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; HISTAMINE RELEASE; MEDICINAL PLANT; MOUSE; NONHUMAN; PLANT ROOT; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PYLORUS LIGATION; STOMACH ACID SECRETION; STOMACH PH; STOMACH ULCER;

ANIMALIA; SOLANACEAE; SOLANUM; SOLANUM PANICULATUM;

EID: 0036745208     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1078/09447110260573137     Document Type: Article

References (40)

1. Barbosa-Filho JM, Agra MF, Oliveira RA, Paulo MQ, Trolin EV, Ataide JR, Bhattacharya J (1991) Chemical and pharmacological investigation of Solanum species of Brazil - a search for solasodne and other potentially useful therapeutic agents. Mem Inst Oswaldo Cruz 86 Suppl 2: 189-191
2. Blankemeyer JT, McWilliams ML, Rayburn JR, Weissenberg M, Friedman M (1998) Developmental toxicology of solamargine and solasonine glycoalkaloids in frog embryos. Food Chem Toxicol 36: 383-389
3. Chew CS (1985) Parietal cell protein kinases. Selective activation of type I e AMP-dependent protein kinase by histamine. J Biol Chem 260: 7540-7550
4. Chiba T, Fisher SK, Park J, Seguin EB, Agranoff BW, Yamada T (1988) Carbamoylcholine and gastrin induce inositol lipid turnover in canine gastric parietal cells. Am J Physiol 255 (1 Pt 1): G99-G105
5. Coimbra R (1958) Notas de Fitoterapia. Catálogo dos Dados Principais sobre Plantas utilizadas em Medicina e Farmácia. 2.ed. Ed. Silva Araujo-Roussel. Rio de Janeiro, Brasil, 241
6. Corrêa M (1984) Dicionário das Plantas Úteis do Brasil. Ministério da Agricultura. Instituto Brasileiro de Desenvolvimento Florestal. Vol III, 395
7. Costa OA (1940) Jurubeba. Rev. Bras. Farmácia 21 (12): 404-416
8. Costa OF (1975) Farmacognosia. 2da. Ed Lisboa-Fundacao Calouste-Gulbenkian, Vol 2, 712-713
9. Crawford L, Myhr B (1995) A preliminary assessment of the toxic and mutagenic potential of steroidal alkaloids in transgenic mice. Food Chem Toxicol 33(3): 191-194
10. Djahanguiri B (1969) The production of acute gastric ulceration by indomethacin in the rat. Scand J Gastroenterol 4: 265-267
11. Farmacopéia Dos Estados Unidos do Brasil (1959) 2da. Ed., 543-544
12. Faucher A, Monnet R (1967) Kinetic study of the inhibition of horse serum cholinesterase by certain steroid alkaloids of Solanum. CR Acd Sci Hebd Seances Acad Sci D 264(18): 224-229
13. Fluck RA, Jaffe MJ (1975) Cholinesterases from plant tissues. VI. Preliminary characterization of enzymes from Solanum melongena L. and Zea mays L. Biochem Biophys Acta 410 (1): 130-134
14. Gaffield W, Keeler RF (1984) Structure and stereochemistry of steroidal amine teratogens. Adv Exp Med Biol 177: 241-251
15. Gilani AH, Shaheen F, Christopoulos A, Mitchelson F (1997) Interactions of ebeinone, an alkaloid from Fritillaria imperialis, and two muscarinic acetylcholine receptor subtypes. Life Sci 60(8): 535-544
16. Goldman H, Rossof CB (1968) Pathogeneses of acute stress ulcers. Am J Pathol 52: 227-236
17. Kitagawa H, Fujiwara M, Osumi Y (1987) Effects of water immersion stress and insulin on gastric acid secretion in rats. Physiol Behav 40: 357-361
18. Leekning ME, Rocca MA (1968) Contribui̧cão para o estudo Quimico dos frutos do Solanum paniculatum L. Rev Fac Farm Odont Araraquara 2(2): 299-300
19. Lorenz W, Doenicke A, Mann G, Uhlig R, Rohde H (1973) Histamine liberation in man and pathogenesis of stress ulcer. Z Gastroenterol 11(4): 297-300
20. Mahmud T, Rafi SS, Scott DL, Wrigglesworth JM, Bjarnason I (1996) Nonsteroid antiinflammatory drugs and uncoupling of mitochondrial oxidative phosphorylation. Arthritis Rheum 39: 1998-2003
21. Martin BK (1963) Accumulation of drug anions in gastric mucosal cells. Nature 198: 896-897
22. Matos AFJ (1987) O Formulário Fitoterápico do prof. Dias da Rocha. Coleção ESAM. Ano XX, Vol CCLLXV, 131-132
23. Menguey R, Desbaillets L (1967) Role of inhibition of gastric mucous secretion in the phenomenon of gastric mucosal injury by indomethacin. Am J Dig Dis 12: 862-866
24. Meyer VK, Bernoulli F (1961) Über die basischen Inhaltstoffe von Solanum paniculatum L. Pharmaceutica Acta Helvetiae 36: 80-96
25. Obrink KJ (1991) Histamine and gastric acid secretion. A review. Scand J Gastroenterol (suppl) 180: 4-8
26. Penna M (1964) Dicionário Brasileiro de Plantas Medicinais. Kosmos, Rio de Janeiro, Brazil 351-352
27. Pfeiffer A, Rochlitz H, Noelke B, Tacke R, Moser U, Mutscheler E, Lambrecht G (1990) Muscarinic receptors mediating acid secretion in isolated rat gastric parietal cell are of M3 type. Gastroenterology 98: 218-222
28. Rahman A, Farooq A, Choudhary MI, Gilani AH, Shaheen F, Noor-e-ain F, Sener B (1994) A new anticholinergic steroidal alkaloid from Fritillaria imperialis of Turkish origin. Planta Med 60(4): 377-379
29. Ripperger H, Budzikiewicz H, Schreiber K (1967a) Jurubin ein stickstoffhaltiges Steroidsaponin neuartigen Strukturtyps aus Solanum paniculatum L; über die Struktur von Paniculidin. Chem Ber. 100 (5): 1725-1740
30. Ripperger H, Schreiber K, Budzikiewicz H (1967b) Isolierung von Neochlorogenin und Paniculogenin aus Solanum paniculatum L. Chem Ber 100: 1741-1752
31. Santos CAM, Torres KR, Leonart R (1988) Plantas Medicinais (Herbarium, flora et scientia). Scientia et labor-Edições da UFPR. 113
32. Schreiber K, Ripperger H (1966) Jurubine, a novel type of steroidal saponin with (25S)-3β-amino-5α-furostane-22α. 26-diol o (26)-β-D-Glucopyranoside structure from Solanum paniculatum L. Tetrahedron Lett 48: 5997-6002
33. Schreiber K, Ripperger H, Budzikiewicz H (1965) (22R:25S)-3 β-amino-5α-spirostan, ein Steroidalkaloid neuartigen Strukturtyps aus Solanum paniculatum L. Tetrahedron Lett 45: 3999-4002
34. Silva MF (1977) Nomes vulgares de plantas amazonicas. Belen, INPA. 178
35. Siqueira NS, Macan A (1976) Cromatografia dos alcalóides da Solanum-paniculatum L. Trib Farm 44(1-2): 101-105
36. Siqueira-Jaccoud RJ, Pereira NA, Lainetti R (1982) Jurubeba. Rev Bras Farm 121-131
37. Somasundaram S, Hayllar H, Rafi S, Wrigglesworth JM, Macpherson AJ, Bjamason I (1995) The Biochemical basis of non-steroid anti-inflammatory drug-induced damage to the gastrointestinal tract: review and a hypothesis. Scand J Gastroenterol 30: 289-299
38. Somasundaram S, Rafi S, Hayllar H, Sigthorsson G, Jacob M, Price AB (1997) Mitochondrial damage: a possible mechanism of the 'topical' phase of NSAID-induced injury to the rat intestine. Gut 41: 344-353
39. Szabo S (1987) Mechanisms of mucosal injury in the stomach and duodenum: time-sequence analysis of morphologic, functional, biochemical and histochemical studies. Scand J Gastroenterol 22 (suppl 127): 21-28
40. Vela SM, Souccar C, Lima-Landman MT, Lapa AJ (1997) Inhibition of gastric acid secretion by the Aqueous extract and purified extracts of Stachytarpheta cayennensis. Planta Med 63(1): 36-39