Calmodulin UAS-constructs and the in vivo roles of calmodulin: Analysis of a muscle-specific phenotype

Genesis (United States)

Volumn 34, Issue 1-2, 2002, Pages 86-90

  Wang, Bo ^a   Bolduc, Clare ^a   Beckingham, Kathy ^a  

^a RICE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALMODULIN; SODIUM CHANNEL;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CARBOXY TERMINAL SEQUENCE; GENE; GENE CONSTRUCT; GENE MUTATION; IN VIVO STUDY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; UAS GENE;

EID: 0036742623     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/gene.10141     Document Type: Article

References (13)

1. Brand AH, Perrimon N. 1993. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118:401-415.
2. Heiman RG, Atkinson RC, Andruss BF, Bolduc C, Kovalick GE, Beckingham K. 1996. Spontaneous avoidance behavior in Drosophila null for calmodulin expression. Proc Natl Acad Sci USA 93:2420-2425.
3. Kink JA, Maley ME, Preston RR, Ling KY, Wallen-Friedman MA, Saimi Y, Kung C. 1990. Mutations in Paramecium calmodulin indicate functional differences between the C-terminal and N-terminal lobes in vivo. Cell 62:165-174.
4. Ling KY, Maley ME, Preston RR, Saimi Y, Kung C. 1994. New non-lethal calmodulin mutations in Paramecium. A structural and functional bipartition hypothesis. Eur J Biochem 222:433-439.
5. 2+ binding sites of calmodulin. J Biol Chem 267:5286-5295.
6. Mukherjea P, Maune JF, Beckingham K. 1996. Interlobe communication in multiple calcium-binding site mutants of Drosophila calmodulin. Protein Sci 5:468-477.
7. Nelson MR, Chazin WJ. 1998. Calmodulin as a calcium sensor. In: Eldik L, Watterson D, editors. Calmodulin and signal transduction. New York: Acdemic Press. p 17-42.
8. Nelson HB, Heiman RO, Bolduc C, Kovalick GE, Whitley P, Stem M, Beckingham K. 1997. Calmodulin point mutations affect Drosophila development and behavior. Genetics 147:1783-1798.
9. 2+-dependent inactivation of L-type calcium channels. Neuron 22:549-558 [erratum, Neuron 1999 22(4): following 893].
10. Rodney GG, Krol J, Williams B, Beckingham K, Hamilton SL. 2001. The carboxy-terminal calcium binding sites of calmodulin control calmodulin's switch from an activator to an inhibitor of RYR1. Biochemistry 40:12430-12435.
11. Sullivan KM, Scott K, Zuker CS, Rubin GM. 2000. The ryanodine receptor is essential for larval development in Drosophila melanogaster. Proc Natl Acad Sci USA 97:5942-5947.
12. Takeshima H, Nishi M, Iwabe N, Miyata T, Hosoya T, Masai I, Hotta Y. 1994. Isolation and characterization of a gene for a ryanodine receptor/calcium release channel in Drosophila melanogaster. FEBS Lett 337:81-87.
13. Zhang M, Tanaka T, Ikura M. 1995. Calcium-induced conformational transition revealed by the solution structure of apo calmodulin. Nat Struct Biol 2:758-767.