Mechanisms for increment of platelet associated IgG and platelet surface IgG and their implications in immune thrombocytopenia associated with chronic viral liver disease

Hepatology Research

Volumn 24, Issue 1, 2002, Pages 23-33

  Doi, Tadashi ^a   Homma, Hisato ^b   Mezawa, Shinichi ^a   Kato, Junji ^a   Kogawa, Katsuhisa ^a   Sakamaki, Sumio ^a   Niitsu, Yoshiro ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Tokeidai Hospital   (Japan)

Author keywords

Anti platelet antibody; Chronic viral liver disease; Immune complex; PAIgG; Platelet surface IgG

Indexed keywords

GLYCOPROTEIN; IMMUNOGLOBULIN G; THROMBOCYTE ANTIBODY;

ADULT; AGED; ANTIBODY BLOOD LEVEL; ANTIGEN ANTIBODY COMPLEX; ARTICLE; ARTIFICIAL EMBOLISM; CELL DESTRUCTION; CHRONIC LIVER DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HEPATITIS B; HEPATITIS C; HUMAN; HYPERSPLENISM; IDIOPATHIC THROMBOCYTOPENIC PURPURA; MACROPHAGE; MALE; PHAGOCYTOSIS; PRIORITY JOURNAL; REGULATORY MECHANISM; SPLEEN ARTERY; THROMBOCYTE COUNT; THROMBOCYTE MEMBRANE; THROMBOCYTE VOLUME; THROMBOCYTOPENIA; THROMBOCYTOPOIESIS;

EID: 0036740453     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1386-6346(02)00010-4     Document Type: Article

References (33)

1. Aster RH. Pooling of platelet in the spleen: role in the pathogenesis of hypersplenic thrombocytopenia. J Clin Invest 1964;45:645-57.
2. Aoki Y, Hirai K, Tanikawa K. Mechanism of thrombo-cytopenia in liver cirrhosis: kinetics of indium-111 tropolone labeled platelets. Eur J Nucl Med 1993;20:123-9.
3. Noguchi H, Hirai K, Aoki Y, Sakata K, et al. Changes in platelet kinetics after a partial splenic arterial embolization in cirrhotic patients with hypersplenism. Hepatology 1995;22:1682-8.
4. Kajiwara E, Akagi K, Azuma K, et al. Evidence for immunological pathogenesis of thrombocytopenia in chronic liver disease. Am J Gastroenterol 1995;90:962-6.
5. Noronha R, Taylor BA, Wild G, et al. Interrelationships between platelet count, platelet IgG, serum IgG, immuno complexes and severity of liver disease. Clin Lab Haematol 1991;13:127-35.
6. George JN. Platelet immunoglobulin G: its significance for the evaluation of thrombocytopenia and for understanding the origin of α-granule proteins. Blood 1990;76:859-70.
7. Kelton JG. The serological investigation of patients with autoimmune thrombocytopenia. Thrombos Haemostas 1995;74:228-33.
8. George JN. Platelet IgG: measurement, interpretation and clinical significance. Prog Hemost Thromb 1991;10:97-126.
9. Mueller- Eckhardt C, Kayser W, Mersch-Baumert K, et al. The clinical significance of platelet-associated IgG: a study on 298 patients with various disorders. Br J Haematol 1980;46:123-31.
10. Kosugi S, Imai Y, Kurata Y, et al. Platelet-associated IgM elevated in patients with chronic hepatitis C contains no anti-platelet autoantibodies. Liver 1997;17:230-7.
11. Tsubakio T, Kurata Y, Yonezawa T, et al. Quantification of platelet-associated IgG with competitive solid-phase enzyme immunoassay. Acta Haematol 1981;66:251-6.
12. George JN, Saucerman S. Platelet IgG, IgA, IgM, and albumin: correlation of platelet and plasma concentrations in normal subjects and in patients with ITP or dysproteinemia. Blood 1988;72:362-5.
13. Christopoulos CG, Kelsy HC, Machin SJ. A flow-cytometric approach to quantitative estimation of platelet surface immunoglobulin G. Vox Sang 1993;64:106-15.
14. Keifel V, Santoso S, Weisheit M, et al. Monoclonal antibody-specific immobilization of platelet antigens (MAIPA): a new tool for the identification of platelets reactive antibodies. Blood 1987;70:1722-6.
15. Sakamaki S, Hirayama Y, Matsunaga T, et al. Transforming growth factor-β1(TGF-β1) induces thrombopoietin from bone marrow stromal cells, which stimulates the expression of TGF-β receptor on megakaryocytes and, in turn, renders them susceptible to suppression by TGF-β1 itself with high specificity. Blood 1999;94:1961-70.
16. Pistiotta AV, Stefanini M, Dameshek W. Studies on platelet X. Morphologic, characteristics of megakaryocytes by phase contrast microscopy in normals and patients with idiopathic thrombocytopenic purpura. Blood 1953;8:703-23.
17. Zeigler Z, Murphy S, Gardner FH. Microscopic platelet size and morphology in various hematologic disorders. Blood 1978;51:479-86.
18. Levin J, Bessman D. The inverse relation between platelet volume and platelet number: Abnormalities in hematologic disease and evidence that platelet size does not correlate with platelet age. J Lab Clin Med 1983;101:295-307.
19. Shirai Y, Kawata S, Tamura S, et al. Plasma transforming growth factor-beta 1 in patients with hepatocellular carcinoma. Comparision with chronic liver diseases. Cancer 1994;73:2275-9.
20. Mayer M, Herrmann I, Kempgens U, et al. In vivo labeling of platelets with 75Se-selenomethionine in patients with hepatic cirrhosis and thrombocytopenia. Thrombos Haemostas 1977;37:47-52.
21. Luzzatto G, de Franchis G, Fabris F. Increased proportion of giant platelets and platelet distribution width are better indicators of altered platelet homeostasis than mean platelet volume in liver. Folia Haematol 1988;115:719-26.
22. Pereira J, Accatino L, Alfaro J, et al. Platelet autoanti-bodies in patients with chronic liver disease. Am J Hematol 1995;50:173-8.
23. Feistauer SM, Penner E, Mayr WR, et al. Target platelet antigens of autoantibodies in patients with primary biliary cirrhosis. Hepatology 1997;25:1343-5.
24. Helmerhorst FM, Smeenk RJT, Hack CE, et al. Interference of IgG, IgG aggregates and immune complexes in tests for platelet autoantibodies. Br J Haematol 1983;55:533-45.
25. Lunel F, Musset L, Cacoub P, et al. Cryoglobulinernia in chronic liver diseases: role of hepatitis C virus and liver damage. Gastroenterology 1994;106:1291-300.
26. Willson RA. Extrahepatic manifestations of chronic viral hepatitis. Am J Gastroenterol 1997;92:4-15.
27. Kelton JG, Smith JW, Santos AV, et al. Platelet IgG Fc receptor. Am J Hematol 1987;25:299-310.
28. King M, Mcdermott P, Schreiber AD. Characterization of the Fc γ receptor on human platelets. Cell Immunol 1990;128:462-79.
29. Barrison IG, Knight ID, Viola L, et al. Platelet associated immunoglobulins in chronic liver disease. Br J Haematol 1981;48:347-50.
30. Pfueller SL, Firkin BG, DeRosbo, et al. Association of increased immune complexes, platelet IgG and serum IgG in chronic active hepatitis. Clin Exp Immunol 1993;54:655-60.
31. Vijayalakshmi P, Giuliani D, Morse BS. Circulating immune complexes and platelet IgG in various diseases. Clin Exp Immunol 1984;58:672-6.
32. Samuel S, Nardi M, Karpatkin M, et al. Differentiation of autoimmune thrombocytopenia from thrombocytopenia associated with immune complex disease: systemic lupus erythematosus, hepatic-cirrhosis, and HIV-1 infection by platelet and serum immunological measurements. Br J Haematol 1999;105:1086-91.
33. Claas FHJ. Immune mechanisms leading to drug-induced blood dyscrasias. Eur J Haematol 1996;57(Suppl):64-8.